Hotels in Esquilino, Rome

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Our top choices for Esquilino hotels

Casa per Ferie Domus Helena

Casa per Ferie Domus Helena
Esquilino
9.4 out of 10, Exceptional, (436)
"All round great stay"
Canada
Mavis
Casa per Ferie Domus Helena

The Cross Hotel

The Cross Hotel
3.0 star property
Esquilino
8.6 out of 10, Excellent, (437)
"The room was clean and the staff were friendly and helpful. Breakfast food was great and they ensure they got plenty of food supply. "
United States
Salvador
The price is RM314
RM402 total
includes taxes & fees
11 Jan - 12 Jan 2026
The Cross Hotel

Napoleon Hotel

Napoleon Hotel
4.0 star property
Esquilino
8.4 out of 10, Very good, (1003)
"Perfect location and great breakfast."
United States
Marcia
Napoleon Hotel

HOTEL MARECHIARO

HOTEL MARECHIARO
Esquilino
8.8 out of 10, Excellent, (16)
"The desk clerk was super friendly and helpful. Hotel was really nice and within walking distance to most everything."
United States
Toni
The price is RM386
RM482 total
includes taxes & fees
14 Jan - 15 Jan 2026
HOTEL MARECHIARO

Hotel Terminal

Hotel Terminal
3.0 star property
Esquilino
7.6 out of 10, Good, (339)
"Convenient location for transport and shopping. "
United States
Shane
Hotel Terminal

Hotel Agorà

Hotel Agorà
Esquilino
7.2 out of 10, Good, (573)
"Great place "
Canada
Francesca
The price is RM231
RM311 total
includes taxes & fees
24 Dec - 25 Dec
Hotel Agorà

Raeli Hotel Siracusa

Raeli Hotel Siracusa
3.0 star property
Esquilino
7.4 out of 10, Good, (837)
"Great service, the staff are very professional, the room was clean, we also enjoyed the breakfast bar with lots of items to choose from. "
Canada
Delon
Raeli Hotel Siracusa

DVE Suite Rome

DVE Suite Rome
Esquilino
9.0 out of 10, Wonderful, (411)
"The room was clean, staff is helpful and accommodating. Breakfast was also decent and the location is central. "
Canada
Jennifer
The price is RM328
RM418 total
includes taxes & fees
9 Jan - 10 Jan 2026
DVE Suite Rome

Roma Vespahouse

Roma Vespahouse
Esquilino
9.2 out of 10, Wonderful, (594)
"Close to great restaurants and the train station. "
Canada
David
Roma Vespahouse

Hotel Flavio Rome

Hotel Flavio Rome
3.0 star property
Esquilino
8.0 out of 10, Very good, (274)
"Staff were very friendly and hotel was in a great area, some homeless people at night but it was safe."
Canada
Soreela
The price is RM456
RM558 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Flavio Rome

Magic Door Rome

Magic Door Rome
Esquilino
8.2 out of 10, Very good, (216)
"All Great "
United Kingdom
Georgi
The price is RM276
RM370 total
includes taxes & fees
5 Jan - 6 Jan 2026
Magic Door Rome

Mecenate Palace

Mecenate Palace
4.0 star property
Esquilino
9.0 out of 10, Wonderful, (1003)
"We have been here twice. The staff is very friendly it’s close to everything and very clean "
Canada
Joseph
The price is RM549
RM675 total
includes taxes & fees
6 Jan - 7 Jan 2026
Mecenate Palace

My Maison 109

My Maison 109
Esquilino
9.0 out of 10, Wonderful, (12)
"Fang fang was so amazing and incredibly helpful, I enjoyed my stay here. "
United States
Jose
The price is RM387
RM473 total
includes taxes & fees
24 Dec - 25 Dec
My Maison 109

Rome Jubilee Stays 2

Rome Jubilee Stays 2
Esquilino
Rome Jubilee Stays 2

Leoni di Giada Guesthouse

Leoni di Giada Guesthouse
Esquilino
9.0 out of 10, Wonderful, (2)
"Equipe de atendimento nota 10. Quarto confortável e agradável, perto do terminal de trem e dos pontos turísticos. Indico e voltarei. "
Brazil
Guilherme
The price is RM208
RM357 total
includes taxes & fees
13 Jan - 14 Jan 2026
Leoni di Giada Guesthouse

Dream Station

Dream Station
Esquilino
9.0 out of 10, Wonderful, (327)
"Excellent location right across from the train station! Felt very safe! Cute colored rooms, and a shared kitchen"
United States
Christina
Dream Station

Hotel Central Lodge

Hotel Central Lodge
Esquilino
9.2 out of 10, Wonderful, (74)
"The staff were excellent, very friendly and helpful. "
United Kingdom
Melissa
The price is RM537
RM662 total
includes taxes & fees
21 Jan - 22 Jan 2026
Hotel Central Lodge

Rome To Stay

Rome To Stay
Esquilino
8.8 out of 10, Excellent, (152)
"Great stay, big shout out to Roberto the owner of Rome to Stay, very helpful and welcoming."
United Kingdom
Patrick
Rome To Stay

Hotel Ciao

Hotel Ciao
1.0 star property
Esquilino
8.2 out of 10, Very good, (181)
"Great stay and staff"
United Kingdom
Julian
The price is RM296
RM364 total
includes taxes & fees
24 Dec - 25 Dec
Hotel Ciao

Chez Liviana

Chez Liviana
Esquilino
Chez Liviana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Esquilino

Find the best Esquilino areas for the activities you enjoy most.

Rome City Centre

Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views.

Rome Historic Centre

Visit the center of Italy’s capital and enjoy traditional Italian food. Relax in old bars and see some of the city’s famous historic sites.

Trastevere

Spend some time visiting places like Basilica of Santa Maria in Trastevere while getting to know Trastevere, and be sure to check out the colourful gardens. You can hop aboard the metro at Trastevere/Min. P. Istruzione Tram Stop or Induno Tram Stop to see more of the area.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

Trevi

Art galleries, churches and museums are just a few things travellers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

Top Esquilino Hotel Reviews

Frequently asked questions

What is Esquilino like?
Esquilino is an historic neighbourhood known for its array of dining options and sightseeing. Are you looking for Esquilino travel tips? Make sure that you visit Piazza Vittorio Emanuele II and Piazza Santa Maria Maggiore while you're in the neighbourhood.
What's the best accommodation in Esquilino?
Based on Expedia customer reviews, Smart Guesthouse is the highest ranked property in Esquilino. This guest house is a short 10-minute walk from Via Nazionale, and it offers free WiFi and Smart TVs. Other favourite options in the area include Casa per Ferie Domus Helena and NH Collection Roma Palazzo Cinquecento.
How many hotels can I expect to find in Esquilino?
If you're searching for places to stay in Rome, Expedia has something to meet your needs with 705 Esquilino hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Esquilino, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals available in Esquilino.
What are the top things to see and do in Esquilino?
Villa Giustiniani Massimo, Palace of the Holy Steps (Santuario della Scala Santa) and Anfiteatro Castrense are some local landmarks to explore in Esquilino. You could also plan a visit to Piazza Vittorio Emanuele II or Piazza Santa Maria Maggiore while you're in the neighbourhood. Don't miss favourite places to visit in the surrounding area, such as Colosseum, Trevi Fountain and Piazza Navona. While you're out sightseeing, Spanish Steps and Piazza di Spagna are a couple of additional sights to visit in Rome.
How can I get around Esquilino and the greater Rome area?
For a quick way to explore the city, catch a ride on metro transit at S Bibiana Station, Vittorio Emanuele Station or Manzoni - Museo della Liberazione Station. If you want to venture out of town, Rome Termini Station is the closest train station. You can also catch a ride at Rome (XRJ-Termini Rail Station).

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