Top 10 Esquilino Hotels of 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Where to stay in Esquilino

Find the best Esquilino areas for the activities you enjoy most.

Rome City Centre

Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views.

See properties

Rome Historic Centre

Visit the center of Italy’s capital and enjoy traditional Italian food. Relax in old bars and see some of the city’s famous historic sites.

See properties

Trastevere

Spend some time visiting places like Basilica of Santa Maria in Trastevere while getting to know Trastevere, and be sure to check out the colourful gardens. You can hop aboard the metro at Trastevere/Min. P. Istruzione Tram Stop or Induno Tram Stop to see more of the area.

See properties

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

See properties

Trevi

Art galleries, churches and museums are just a few things travellers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

See properties

Top Esquilino Hotel Reviews

Casa per Ferie Domus Helena

10/10 Excellent

"Good location, just around the corner from the Metro. 15 min stroll to Termini station and approx 20 min to Coliseum. Breakfast was good, eggs, bacon, pastries, cereal. Vending machine on ground floor for cold drinks. Can get kettle & cups for room if you ask. Lovely lady on reception most mornings. Very clean, only gripe hubby didn’t like the bed."

Hotel Palladium Palace

8/10 Good

"Staff was exceptional and the facilities were well maintained and clean. Breakfast was very good too. However, our room had some inconveniences. First and foremost, we couldn't use the overhead shower because if we did, it flooded the entire bathroom due to the spray going everywhere (instead of just straight down) and the design of the shower stall doors which didn't fully seal off the shower stall. Additionally, we found it somewhat inconvenient there were no towel racks or hangars of any kind. Overall, was a good stay though and we appreciated the staff's professionalism and helpfulness."

Hotel Valentino Palace

10/10 Excellent

"Well located , great staff, helped us with the different things we can Do around . Very close to the train station which made our trip even more easy. We booked 2 rooms one was fully renovated the other was an old room with AC not working properly n the bathroom was very Old which made it less attractive ."

Frequently asked questions

What is Esquilino like?

Esquilino is an historic neighbourhood known for its array of dining options and sightseeing. Are you looking for Esquilino travel tips? Make sure that you visit Piazza Vittorio Emanuele II and Historic Museum of the Liberation while you're in the neighbourhood.

What's the best accommodation in Esquilino?

Based on our traveller data, Napoleon Hotel is one of the top choices for your stay in Esquilino. This hotel is a short 14-minute walk from Teatro dell'Opera di Roma, and it offers a restaurant and a fitness centre. Other good options for your stay in the neighbourhood include Hotel Palladium Palace and Rome Experience Hostel.

How many hotels can I expect to find in Esquilino?

If you're searching for places to stay in Rome, Expedia has something to meet your needs with 753 Esquilino hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Esquilino, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals available in Esquilino.

What are the top things to see and do in Esquilino?

Palace of the Holy Steps (Santuario della Scala Santa), Trofei di Mario and Porta Magica are some local landmarks to explore in Esquilino. You could also plan a visit to Piazza Vittorio Emanuele II or Historic Museum of the Liberation while you're in the neighbourhood. Don't miss favourite places to visit in the surrounding area, such as Trevi Fountain, Spanish Steps and Piazza Navona. While you're out sightseeing, St. Peter's Basilica and Vatican Museums are a couple of additional sights to visit in Rome.

How can I get around Esquilino and the greater Rome area?

For a quick way to explore the city, catch a ride on metro transit at S Bibiana Station, Vittorio Emanuele Station or Manzoni - Museo della Liberazione Station. If you want to venture out of town, Rome Termini Station is the closest train station. You can also catch a ride at Rome (XRJ-Termini Rail Station).

Hotels in Esquilino, Rome

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Esquilino hotels

1. Aethel Guesthouse

2. ReRent Rooms - 81 MANZONI GUESTHOUSE

3. Casa per Ferie Domus Helena

4. Napoleon Hotel

5. The Cross Hotel

6. Bed and Breakfast Rhome86

7. DVE Suite Rome

8. Nice2CU

9. Pepe's Place - Guesthouse Manzoni

10. Hotel Ciao

11. Conte Residence

12. Hotel Maryelen

13. Smart Guesthouse

14. HOTEL MARECHIARO

15. Hotel Emona Aquaeductus

16. Roman Holiday Suites

17. The BlueHostel

18. VICTORIA SUITES

19. Dream Station

20. Hotel Orazia

Where to stay in Esquilino

Rome City Centre

Rome Historic Centre

Trastevere

Monti

Trevi

Top Esquilino Hotel Reviews

Casa per Ferie Domus Helena

Frequently asked questions

Explore a world of travel with Expedia