Top 10 Esquilino Hotels of 2026

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Property	Property class	Guest rating
Smart Guesthouse	3.0 star property	9.6 Exceptional 121 reviews	View
Hotel Emona Aquaeductus	4.0 star property	9.0 Wonderful 66 reviews	View
Mecenate Palace	4.0 star property	9.0 Wonderful 1,011 reviews	View
Hotel Latinum	4.0 star property	9.0 Wonderful 27 reviews	View
The Cross Hotel	3.0 star property	8.8 Excellent 592 reviews	View

Where to stay in Esquilino

Find the best Esquilino areas for the activities you enjoy most.

A bustling outdoor market with food stalls, umbrellas, and a crowd of people.

Rome City Centre

Trevi Fountain and Piazza Navona are a few top attractions in Rome City Centre. Hop around the city on the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station and check out the area's fascinating museums, stunning cathedral and stunning river views.

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A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Visit the center of Italy’s capital and enjoy traditional Italian food. Relax in old bars and see some of the city’s famous historic sites.

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The Colosseum in Rome, Italy, with tourists walking around and taking photos.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

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A restaurant named Ditta Trinchetti with outdoor seating and chalkboard menus.

Trastevere

Spend some time visiting places like Basilica of Santa Maria in Trastevere while getting to know Trastevere, and be sure to check out the colourful gardens. You can hop aboard the metro at Trastevere/Min. P. Istruzione Tram Stop or Induno Tram Stop to see more of the area.

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Trevi

Art galleries, churches and museums are just a few things travellers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

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Top Esquilino Hotel Reviews

Mecenate Palace

10/10 Excellent

"Very helpful staff, very clean, cozy and welcoming. The location is also amazing and has lots of restaurants and stores around. Highly recommend Mecenate Palace!"

Kennedy Hotel

8/10 Good

"Room was an apartment in the end, in an annex from the main building over the road, a short walk away. Was one double sofa bed, and one double bed and a camp bed in bedroom. Shower door was hanging on for dear life. Breakfast was a little limited, and no hot options but overall each of the 4 of us found something. Staff are 10/10 and couldn’t be more helpful. Baggage storage for check out. Short 5 min walk to Termini for train, bus and metro. Various restaurants nearby."

Casa per Ferie Domus Helena

10/10 Excellent

"Everything about the Domus Helena was perfect for our 8-day visit to Rome. To start, the staff was amazing and helpful. They gave us tips on where to eat and what to visit and were always very accomodating to what we needed. The AC in the rooms was a welcome relief from the July heat, and the room was always clean and fresh. We really appreciated the morning breakfast with a vast assortment of food and goodies to munch on before we started our day. To give an idea, the hotel is about a 5-minute walk away from the nearest Metro station and about a 12-minute walk from the Colosseum. We will definitely stay at the Domus Helena on our next visit to Rome!"

Hotel Giubileo

8/10 Good

"In an ideal location right next to st Mary basilica, loads of shops, restaurants and bars only 30-40m walk from the likes of the Colosseum, the Spanish steps, Trevi fountain and also near transport links if you don't fancy walking it. The only issue I had with the room, which tbf wasn't too much of an issue as I wasn't in the room that much but the outside windows [the windows were double with an inner and outer window] were cracked and the toilet seat slipped but these are minor things and not to put anybody off staying here."

Frequently asked questions

What is Esquilino like?

Esquilino is an historic neighbourhood known for its array of dining options and sightseeing. Are you looking for Esquilino travel tips? Make sure that you visit Piazza Vittorio Emanuele II and Palace of the Holy Steps (Santuario della Scala Santa) while you're in the neighbourhood.

What's the best accommodation in Esquilino?

Based on our traveller data, Napoleon Hotel is one of the top choices for your stay in Esquilino. This hotel offers a restaurant and a fitness centre. Other good options for your stay in the neighbourhood include Rome Experience Hostel and Hotel Palladium Palace.

How many hotels can I expect to find in Esquilino?

If you're searching for places to stay in Rome, Expedia has something to meet your needs with 753 Esquilino hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Esquilino, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals available in Esquilino.

What are the top things to see and do in Esquilino?

Palace of the Holy Steps (Santuario della Scala Santa), Anfiteatro Castrense and Trofei di Mario are some local landmarks to explore in Esquilino. You could also plan a visit to Piazza Vittorio Emanuele II or Piazza Santa Maria Maggiore while you're in the neighbourhood. Don't miss favourite places to visit in the surrounding area, such as Trevi Fountain, Spanish Steps and Piazza Navona. While you're out sightseeing, St. Peter's Basilica and Piazza di Spagna are a couple of additional sights to visit in Rome.

How can I get around Esquilino and the greater Rome area?

For a quick way to explore the city, catch a ride on metro transit at S Bibiana Station, Vittorio Emanuele Station or Manzoni - Museo della Liberazione Station. If you want to venture out of town, Rome Termini Station is the closest train station. You can also catch a ride at Rome (XRJ-Termini Rail Station).

Hotels in Esquilino, Rome

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Our top choices for Esquilino hotels

1. The Cross Hotel

2. Napoleon Hotel

3. Hotel Central Lodge

4. DVE Suite Rome

5. NH Collection Roma Palazzo Cinquecento

6. Mecenate Palace

7. Smart Guesthouse

8. Hilton Garden Inn Rome Colosseum

9. Casa per Ferie Domus Helena

10. Hotel Palladium Palace

11. Taormina

12. Kennedy Hotel

13. Hotel Orazia

14. Roma Vespahouse

15. Hotel Ariston

16. HOTEL MARECHIARO

17. Mercure Roma Centro St. John

18. Hotel Morgana

19. Hotel Aphrodite

20. Hotel RomAntica

Compare popular hotels in Esquilino

Where to stay in Esquilino

Rome City Centre

Rome Historic Centre

Monti

Trastevere

Trevi

Top Esquilino Hotel Reviews

Mecenate Palace

Frequently asked questions

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