A large white dome building with a red brick base, surrounded by green trees and a clear blue sky.

Central Missouri Spa Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Central Missouri Hotels with Spa

Tonight
29 Aug - 30 Aug
Tomorrow
30 Aug - 31 Aug
Next weekend
4 Sept - 6 Sept
In two weeks
11 Sept - 13 Sept

Our top choices for Central Missouri hotels with a spa

A lakeside bar named "FIRE ICE" with outdoor seating and a view of the lake.
A spacious lobby with a high ceiling, stone accents, and a central fireplace.
An outdoor seating area with a fire pit, chairs, and a view of a lake at sunset.
A large indoor swimming pool with clear water, surrounded by large windows offering views of greenery and a stone building.

1. Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa
Lake Ozark
  • Luxurious lakeside retreat with rejuvenating spa treatments and tranquil Japanese gardens for ultimate relaxation.
RM392
RM520 total
includes taxes & fees
27 Sept - 28 Sept
Lodge Of Four Seasons Golf Resort, Marina & Spa
A hotel room with two beds, a nightstand, a cabinet, and a wall-mounted artwork.
A poolside area with stone walls and a bar.
A group of people dining at an outdoor table with a view of a body of water and city lights in the background.
An aerial view of a marina at dusk with illuminated buildings, docks, and boats.

2. Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
Lake Ozark
  • Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.
RM466
RM656 total
includes taxes & fees
7 Sept - 8 Sept
Camden on the Lake Resort & Spa
A thatched-roof building with a sign reading "TIKI HUT POOL BAR".
A deck with a view of a lake, dock, and chairs.
A spacious lobby with a stone fireplace, comfortable seating, and a large mural on the ceiling.
A waterfront view with a dock, a marina, and a building with balconies overlooking the water.

3. Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
Osage Beach
  • Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.
RM576
RM701 total
includes taxes & fees
1 Sept - 2 Sept
Margaritaville Lake Resort Lake of the Ozarks
A bar area with wooden counters and stone accents, a stone wall, and a wooden door.
A stone gazebo with a stone pathway leading to it, surrounded by well-maintained grass and a pond.
A multi-story hotel with balconies, a pond in front, and a golf course nearby.
A balcony with two chairs and a table, overlooking a golf course and a lake.

4. The Lodge at Old Kinderhook Golf Resort

The Lodge at Old Kinderhook Golf Resort
Camdenton
  • Revitalise at this lakeside retreat with full-service spa, golf course, and dual pools for ultimate relaxation.
RM721
RM837 total
includes taxes & fees
2 Sept - 3 Sept
The Lodge at Old Kinderhook Golf Resort
A room with a bed, a desk with a computer, and a shelf with toiletries.
A room with a large window, a ceiling fan, a sofa, a table with chairs, and a lamp.
A dining area with a large wooden table and ornate chairs, a ceiling fan, and framed artwork on the walls.
A bar area with a polished wooden counter, a flat-screen TV mounted on the wall, and a framed picture above the counter.

5. The Courtland Hotel and Day Spa

The Courtland Hotel and Day Spa
Fort Scott
  • Tranquil historic hotel offers rejuvenating spa escape with four serene treatment rooms for ultimate relaxation.
RM346
RM400 total
includes taxes & fees
30 Aug - 31 Aug
The Courtland Hotel and Day Spa
A spa area with a massage table, a hot tub, and a grill.
A living room with a fireplace, a dining area with a round table, and a balcony with a view.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.
A hot tub, a fire pit, and a view of a lake.

6. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
RM1,374
RM1,579 total
includes taxes & fees
30 Aug - 31 Aug
Hermann Hill
View all properties

Choose what matters most at spa hotels in Central Missouri

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Central Missouri Hotel Reviews

Econo Lodge Truman Inn

Econo Lodge Truman Inn

8/10 Good
"clean room, very friendly staff."
sondra 4-night trip
Posted 18 hours ago
Econo Lodge Truman Inn
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

8/10 Good
"The coffee shop doesn't open until 7 and the pools do not open until 10 and 11. Other that that it was great."
Holli 3-night trip
Posted 23 hours ago
Margaritaville Lake Resort Lake of the Ozarks
Baymont by Wyndham Rolla

Baymont by Wyndham Rolla

8/10 Good
"Ok stay. Was there for short period. Room was clean and quiet"
Carlton 1-night trip
Posted 23 hours ago
Baymont by Wyndham Rolla
Inn at Grand Glaize

Inn at Grand Glaize

10/10 Excellent
"Definitely will book again on my next visit! Booked for 2 days, then 3, now 4! Hot tub WOW! I almost mistaken for the pool! & Sauna area was The pool was open 24 hrs! property are charm & makes me want to look up its past! & The pool was awesome & open 24 hrs a day!"
Gina 2-night trip
Posted 2 days ago
Inn at Grand Glaize

Explore a world of travel with Expedia