Hotels near Wilkes Regional

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Wilkes Regional hotels

Hampton Inn Winston-Salem Hanes Mall

Hampton Inn Winston-Salem Hanes Mall
2.5 star property
1 km from Wilkes Regional
9.2 out of 10, Wonderful, (1005)
"Super friendly staff, very clean and good breakfast "
United States
jane
The price is RM428
RM484 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Winston-Salem Hanes Mall

Home2 Suites by Hilton Winston-Salem Hanes Mall

Home2 Suites by Hilton Winston-Salem Hanes Mall
3.0 star property
1.8 km from Wilkes Regional
9.2 out of 10, Wonderful, (485)
"Nearby Mall and restaurants"
United States
Pablo
The price is RM428
RM484 total
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites by Hilton Winston-Salem Hanes Mall

Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall

Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall
2.5 star property
1.3 km from Wilkes Regional
9.0 out of 10, Wonderful, (667)
"The room was perfect and clean and the staff was very welcoming and friendly!"
United States
Kelley
The price is RM446
RM503 total
includes taxes & fees
5 Jan - 6 Jan 2026
Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall

Springhill Suites by Marriott Winston-Salem Hanes Mall

Springhill Suites by Marriott Winston-Salem Hanes Mall
3.0 star property
2 km from Wilkes Regional
9.0 out of 10, Wonderful, (1004)
"Check in was quick and easy and the staff was friendly. "
United States
Roxanne
The price is RM433
RM490 total
includes taxes & fees
11 Jan - 12 Jan 2026
Springhill Suites by Marriott Winston-Salem Hanes Mall

Comfort Suites Hanes Mall

Comfort Suites Hanes Mall
2.5 star property
0.7 km from Wilkes Regional
8.8 out of 10, Excellent, (1003)
"Good comfortable stay, will recommend "
United States
Marvin
The price is RM375
RM433 total
includes taxes & fees
31 Dec - 1 Jan 2026
Comfort Suites Hanes Mall

Hilton Garden Inn Winston-Salem/Hanes Mall

Hilton Garden Inn Winston-Salem/Hanes Mall
3.0 star property
2.4 km from Wilkes Regional
8.8 out of 10, Excellent, (720)
"The room was very comfortable ,the staff was friendly and helpful great stay Thank You Jay "
United States
Jay
The price is RM481
RM543 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Winston-Salem/Hanes Mall

Residence Inn by Marriott Winston-Salem Hanes Mall

Residence Inn by Marriott Winston-Salem Hanes Mall
3.0 star property
2.4 km from Wilkes Regional
8.8 out of 10, Excellent, (389)
"Room was spotless and front desk staff was amazing!!! Breakfast food was ok. Would stay here again"
United States
LaMarr
The price is RM434
RM490 total
includes taxes & fees
19 Jan - 20 Jan 2026
Residence Inn by Marriott Winston-Salem Hanes Mall

Courtyard by Marriott Winston-Salem Hanes Mall

Courtyard by Marriott Winston-Salem Hanes Mall
3.0 star property
1.3 km from Wilkes Regional
8.4 out of 10, Very good, (711)
"Clean Room, nice staff Would definitely stay here again "
United States
Dan
The price is RM397
RM449 total
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard by Marriott Winston-Salem Hanes Mall

Sleep Inn Hanes Mall

Sleep Inn Hanes Mall
2.5 star property
Williamsburg Square, 0.9 km from Wilkes Regional
7.8 out of 10, Good, (1005)
"Great stay! "
United States
Raphel
The price is RM283
RM329 total
includes taxes & fees
12 Jan - 13 Jan 2026
Sleep Inn Hanes Mall

WoodSpring Suites Winston-Salem near Hanes Mall

WoodSpring Suites Winston-Salem near Hanes Mall
2.5 star property
2 km from Wilkes Regional
7.8 out of 10, Good, (267)
"friendly staff it was great"
United States
Brandi
The price is RM300
RM339 total
includes taxes & fees
31 Dec - 1 Jan 2026
WoodSpring Suites Winston-Salem near Hanes Mall

Best Western Plus Hanes Mall Hotel

Best Western Plus Hanes Mall Hotel
2.5 star property
2 km from Wilkes Regional
7.6 out of 10, Good, (1001)
"Clean and good breakfast friendly staff"
United States
Raymond
The price is RM331
RM374 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Hanes Mall Hotel

Suburban Studios Winston-Salem near Hanes Mall

Suburban Studios Winston-Salem near Hanes Mall
2.0 star property
Williamsburg Square, 0.8 km from Wilkes Regional
7.0 out of 10, Good, (268)
"clean room, staff, allowed me to check is early."
United States
Gary
The price is RM207
RM233 total
includes taxes & fees
28 Jan - 29 Jan 2026
Suburban Studios Winston-Salem near Hanes Mall

Quality Inn & Suites Hanes Mall

Quality Inn & Suites Hanes Mall
2.5 star property
2.4 km from Wilkes Regional
6.8 out of 10, (1001)
"Yes, the hotel met my expectations and staffs very nice."
United States
Isaul
The price is RM225
RM254 total
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn & Suites Hanes Mall

Red Roof Inn Winston-Salem

Red Roof Inn Winston-Salem
2.0 star property
0.7 km from Wilkes Regional
5.4 out of 10, (426)
"Clean rooms "
United States
Shirley
The price is RM279
RM315 total
includes taxes & fees
31 Dec - 1 Jan 2026
Red Roof Inn Winston-Salem

La Quinta Inn & Suites by Wyndham Winston-Salem

La Quinta Inn & Suites by Wyndham Winston-Salem
3.0 star property
0.7 km from Wilkes Regional
8.6 out of 10, Excellent, (19)
"Best La Quinta we have stayed at in a few years. Room was great as was the location near other amenities."
United States
Melvin
The price is RM284
RM321 total
includes taxes & fees
1 Jan - 2 Jan 2026
La Quinta Inn & Suites by Wyndham Winston-Salem

Summit Street Inns

Summit Street Inns
3.5 star property
6.2 km from Wilkes Regional
9.8 out of 10, Exceptional, (230)
"Great Hotel! Favorite place to stay in Winston Salem."
United States
Pedro
The price is RM540
RM610 total
includes taxes & fees
4 Jan - 5 Jan 2026
Summit Street Inns

The Historic Brookstown Inn, Trademark Collection by Wyndham

The Historic Brookstown Inn, Trademark Collection by Wyndham
3.5 star property
6.4 km from Wilkes Regional
9.6 out of 10, Exceptional, (1009)
"Very nice hotel, with a good breakfast"
United States
David
The price is RM452
RM511 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Historic Brookstown Inn, Trademark Collection by Wyndham

The Zevely Inn

The Zevely Inn
3.0 star property
6.4 km from Wilkes Regional
9.6 out of 10, Exceptional, (138)
"Great breakfast - innkeeper gave great suggestions for things to do in the area. "
United States
Regina
The Zevely Inn

Holiday Inn Express & Suites Winston Salem Sw Clemmons by IHG

Holiday Inn Express & Suites Winston Salem Sw Clemmons by IHG
2.5 star property
7.9 km from Wilkes Regional
9.4 out of 10, Exceptional, (483)
"Good breakfast and very comfortable bed also very clean"
United States
Joseph
The price is RM421
RM476 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Winston Salem Sw Clemmons by IHG

The Shaffner Inn

The Shaffner Inn
3.0 star property
6.4 km from Wilkes Regional
9.2 out of 10, Wonderful, (198)
"Lovely stay! Can be a little noisy at night as its so close to the interstate but a really nice property and manager is super nice and helpful! "
United States
Elizabeth
The Shaffner Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Wilkes Regional Hotel Reviews

Hotels near other Wilkes Regional attractions

Frequently asked questions

What's the area like around Wilkes Regional?
Wilkes Regional is located in Winston-Salem. This family-friendly area is known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 19 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Wilkes Regional?
La Quinta Inn & Suites by Wyndham Winston-Salem is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.7 km) from Wilkes Regional. Other good options close by include Sleep Inn Hanes Mall and Red Roof Inn Winston-Salem.
How many hotels will I find close to Wilkes Regional?
Expedia has 19 hotels and other accommodation options within a mile from Wilkes Regional.
If I need to cancel the hotel reservation for my stay near Wilkes Regional, will I receive a refund?
Yes, most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to get the top deals on offer near Wilkes Regional.
What can I see and do near Wilkes Regional?
Study the collections at Old Salem, Reynolda House Museum of American Art or Southeastern Center for Contemporary Art. You might spend a leisurely day outdoors at Reynolda Gardens and Hobby Park. Attractions like Theatre Alliance and Frank L. Horton Museum Center highlight the local culture.