Hotels in Santo Spirito, Florence
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Santo Spirito hotels
1. Hotel Horto Convento
Hotel Horto ConventoSanto Spirito
9.8 out of 10, Exceptional, (698 reviews)
"Staff was friendly and helpful and the establishment is clean and modern!"
Giuliana
The price is RM667
RM800 total
includes taxes & fees
23 Aug - 24 Aug
2. UNA Hotels Vittoria Firenze
UNA Hotels Vittoria FirenzeSanto Spirito
8.4 out of 10, Very good, (1,000 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"
Glenn
The price is RM381
RM486 total
includes taxes & fees
4 Aug - 5 Aug
3. Ottantotto Firenze
Ottantotto FirenzeSanto Spirito
9.6 out of 10, Exceptional, (175 reviews)
"Really beautiful property and wonderful room. Hotel is immaculately clean and we thought the hotel had been renovated to a beautiful finish. We let the hotel know we were staying for our 10 year anniversary, and a bottle of Prosecco was left in our room with a note, which was extremely kind. A great location to stay in, just across the river. Passcode is provided for front door so can come and go as please. Have booked to stay in again in October!"
Samantha
The price is RM890
RM1,045 total
includes taxes & fees
4 Aug - 5 Aug
4. Casa Santo Nome di Gesù
Casa Santo Nome di GesùSanto Spirito
8.8 out of 10, Excellent, (376 reviews)
"Excellent location and wonderful staff in a unique building with an amazing history."
Matthew
The price is RM504
RM611 total
includes taxes & fees
6 Aug - 7 Aug
5. La Torre Del Cestello
La Torre Del CestelloSanto Spirito
9.0 out of 10, Wonderful, (286 reviews)
"Only thing good view and location"
Karen
The price is RM411
RM518 total
includes taxes & fees
11 Aug - 12 Aug
6. Palazzo Mannaioni Suites
Palazzo Mannaioni SuitesSanto Spirito
9.2 out of 10, Wonderful, (1,151 reviews)
"Lovely place, perfect location. Easy to access!"
Jeanel
The price is RM678
RM812 total
includes taxes & fees
9 Aug - 10 Aug
7. La Fonderia Firenze
La Fonderia FirenzeSanto Spirito
9.6 out of 10, Exceptional, (183 reviews)
"Really nice, handy location"
Kate
The price is RM483
RM588 total
includes taxes & fees
24 Aug - 25 Aug
8. Hotel Palazzo Guadagni
Hotel Palazzo GuadagniSanto Spirito
9.2 out of 10, Wonderful, (212 reviews)
"Historic vibes, clean room, nice view, helpful staff.
Breakfast was included and all you can eat. Food was fresh and coffee was good."
Samuel
The price is RM1,034
RM1,194 total
includes taxes & fees
11 Aug - 12 Aug
9. 1900 Artevita
1900 ArtevitaSanto Spirito
8.8 out of 10, Excellent, (198 reviews)
"Great place, very clean and as described in the listing. It has a good AC for the summer months and I highly recommend it."
Jose Felipe
The price is RM394
RM490 total
includes taxes & fees
20 Aug - 21 Aug
10. Hotel Firenze 2000
Hotel Firenze 2000Santo Spirito
7.2 out of 10, Good, (201 reviews)
"Staff very good ! Good ! clean room"
Salomon
The price is RM453
RM541 total
includes taxes & fees
3 Sept - 4 Sept
11. Oltrarno Splendid
Oltrarno SplendidSanto Spirito
10.0 out of 10, Exceptional, (132 reviews)
"Amazing location, charming hotel and great breakfast"
Carin
The price is RM1,021
RM1,189 total
includes taxes & fees
23 Aug - 24 Aug
12. AdAstra Suites
AdAstra SuitesSanto Spirito
9.8 out of 10, Exceptional, (235 reviews)
"This was our second time visiting Florence, staying at Astra. We loved the beauty of the rooms and surrounding gardens. The staff were very nice and helpful. It's the perfect blend of amenities and self-service for us. We had a B&B-style breakfast and service with 5-star rooms and vibes."
Gary
The price is RM1,263
RM1,455 total
includes taxes & fees
4 Aug - 5 Aug
13. Torre di Bellosguardo
Torre di BellosguardoSanto Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
Brad
The price is RM2,298
RM2,594 total
includes taxes & fees
14 Aug - 15 Aug
14. Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per FerieSanto Spirito
8.8 out of 10, Excellent, (232 reviews)
"I had a lovely stay! Staff were helpful"
Alloura
The price is RM308
RM396 total
includes taxes & fees
5 Aug - 6 Aug
15. Drom Florence Rooms & Apartments
Drom Florence Rooms & ApartmentsSanto Spirito
9.8 out of 10, Exceptional, (152 reviews)
"We had a very nice stay. Claudia was very friendly and service minded
The place serves continental breakfast - and is a good idea to supplement it a little bit!
Nice and quiet area, where you can walk to most things
We can only recommend it
Else Marie Hansen
May 2026"
Else Marie
The price is RM728
RM857 total
includes taxes & fees
2 Sept - 3 Sept
16. Appartamenti degli Artisti by Mmega
Appartamenti degli Artisti by MmegaSanto Spirito
8.6 out of 10, Excellent, (42 reviews)
"We stayed with our children and the space was excellent and the location was close enough to walk to everything. "
Juliet
The price is RM311
RM775 total
includes taxes & fees
5 Aug - 6 Aug
17. B&B Mia Palace
B&B Mia PalaceSanto Spirito
8.4 out of 10, Very good, (123 reviews)
"Breakfast was excellent and what a lovely host. "
Wayne
The price is RM360
RM453 total
includes taxes & fees
4 Aug - 5 Aug
18. Palazzo Oliveto
Palazzo OlivetoSanto Spirito
7.6 out of 10, Good, (106 reviews)
"I really enjoyed my stay here. The host was also extremely kind and helpful."
Mary Mariam
The price is RM257
RM339 total
includes taxes & fees
30 Aug - 31 Aug
19. Residenza D'Epoca Al Numero 8
Residenza D'Epoca Al Numero 8Santo Spirito
9.0 out of 10, Wonderful, (165 reviews)
"Excellent place"
Laura Patricia
The price is RM424
RM532 total
includes taxes & fees
16 Aug - 17 Aug
20. SPIRIT OF FLORENCE Boutique Rooms
SPIRIT OF FLORENCE Boutique RoomsSanto Spirito
10.0 out of 10, Exceptional, (26 reviews)
"Easy check in and very helpful and polite "
Remi
The price is RM813
RM951 total
includes taxes & fees
26 Aug - 27 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santo Spirito
Find the best Santo Spirito areas for the activities you enjoy most.
Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza del Duomo while you're exploring the neighbourhood.
San Giovanni
If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Signoria are top sights worth seeing.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.
