Santa Clara hotels from RM185

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Our top choices for Santa Clara hotels

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1852)
Escape at this Tocumen resort where lush gardens create a peaceful retreat. Just minutes from PTY airport with free shuttle service, guests enjoy 2 tennis courts, casino, and La Veranda restaurant. The serene pool area offers a calm setting after exploring nearby Metromall.

"Clean room and friendly staff "
United States
Delcides
The price is RM510
RM561 total
includes taxes & fees
22 Dec - 23 Dec
Riande Aeropuerto Hotel & Casino

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4700)
Immerse yourself in Panama City elegance just minutes from Avenida Balboa and Via Espana. This luxurious hotel offers 3 restaurants serving international cuisine, an inviting outdoor pool, and complimentary breakfast. Iglesia del Carmen Station is only 11 minutes away.

"Awesome great place to stay "
United States
Herbert
The price is RM446
RM490 total
includes taxes & fees
12 Jan - 13 Jan 2026
Hotel Riu Plaza Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (642)
Unwind at this premium Panama City retreat featuring an 18-hole golf course and rejuvenating spa treatments. Just minutes from Multiplaza Pacific Mall, guests enjoy 2 restaurants serving local cuisine, a refreshing outdoor pool, and attentive service.

"As usual the stay was amazing in this hotel"
United States
Jose
The price is RM914
RM1,006 total
includes taxes & fees
17 Jan - 18 Jan 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1002)
Located in San Miguelito, this hotel offers easy access to Multiplaza Pacific Mall and Metromall Panama. Enjoy international cuisine at Centro restaurant, take a refreshing swim, or work out at the fitness centre. Guests praise the exceptional staff.

"The hotel is conveniently close to the airport and shopping centres. "
United States
Samantha
The price is RM412
RM454 total
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard by Marriott Panama Metromall

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1119)
Experience international cuisine at Fontanella restaurant and take a dip in the outdoor pool at this Panama City hotel. Just 5 minutes from Multiplaza Pacific Mall and Avenida Balboa, guests love the helpful staff and complimentary breakfast.

"The hotel is in a great location in Panama. Great amenities excellent breakfast."
United States
Maria
The price is RM399
RM439 total
includes taxes & fees
10 Jan - 11 Jan 2026
Ramada Plaza by Wyndham Panama Punta Pacifica

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.4 out of 10, Very good, (1004)
"Wonderful staff and easy checkin!"
United States
Kristin
The price is RM340
RM374 total
includes taxes & fees
3 Jan - 4 Jan 2026
Radisson Hotel Panama Canal

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (994)
Enjoy Panama City from this Art Deco resort offering an outdoor pool, 3 restaurants, and 2 bars. The Sheraton Grand sits minutes from Multiplaza Pacific Mall with free WiFi and parking. Guests praise the helpful staff and excellent condition of this spa-focused property.

"Was amazing food was delicious and stay was great "
United States
Amanda
The price is RM516
RM568 total
includes taxes & fees
9 Jan - 10 Jan 2026
Sheraton Grand Panama

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (163)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is RM293
RM511 total
includes taxes & fees
3 Jan - 4 Jan 2026
Arcadia Condo Suites

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (127)
Relax at this upscale Panama City hotel featuring a spa, restaurant and 2 bars. Just a 15-minute walk to Avenida Balboa and Cinta Costera, with Albrook Shopping Mall only 5 minutes by car. Iglesia del Carmen Station is 6 minutes away on foot.

"Great hotel fair price"
United States
Santiago
The price is RM639
RM703 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hyatt Regency Panama City

Hotel Milan

Hotel Milan
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (429)
Wake up refreshed at this convenient Panama City hotel, just a short walk from Iglesia del Carmen Station. Free WiFi and parking complement the on-site restaurant Milan serving 3 meals daily. Explore nearby Avenida Balboa and Cinta Costera with ease.

"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is RM163
RM179 total
includes taxes & fees
22 Dec - 23 Dec
Hotel Milan

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2137)
Situated near Avenida Balboa and Cinta Costera, this Panama City hotel offers international cuisine at Restaurant del Loft Coral. Guests can enjoy hot stone massages, swim in the outdoor pool, or work out in the fitness centre while appreciating the free breakfast.

"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is RM440
RM484 total
includes taxes & fees
28 Dec - 29 Dec
Plaza Paitilla Inn Hotel

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1003)
"Great place and location, excellent food choices! "
United States
Francisco
The price is RM929
RM1,022 total
includes taxes & fees
8 Jan - 9 Jan 2026
The Westin Playa Bonita Panama

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador
8.2 out of 10, Very good, (190)
Surrounded by coastal charm, this hotel offers 6 restaurants and 3 bars for diverse dining experiences. Free breakfast, WiFi, and parking enhance every stay, with Amador Causeway and Albrook Shopping Mall just minutes away.

"Perfect location, nice rooms, nice views"
United States
Ever
The price is RM251
RM276 total
includes taxes & fees
22 Dec - 23 Dec
MARINN Tropical Vibes Hotel

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1610)
"Friendly staff. "
United States
Thessely
The price is RM208
RM229 total
includes taxes & fees
24 Dec - 25 Dec
Principe Hotel and Suites

Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama
3.5 star property
Bella Vista
7.6 out of 10, Good, (705)
Discover Panama City's vibrant scene from this hotel near Avenida Balboa and Cinta Costera. After sightseeing, unwind in the outdoor pool, sauna, or steam room. Guests praise the helpful staff and overall value at this well-located retreat.

"The breakfast was great, I love the pool."
United States
Estefani
The price is RM210
RM231 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hospedium Princess Hotel Panama

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1004)
Relax in this Panama City sanctuary near Avenida Balboa and Cinta Costera. Unwind in the full-service spa, take a dip in the indoor pool, or energise at the fitness centre. Guests love the delicious breakfast and attentive staff. Albrook Shopping Mall is nearby.

"I loved my stay! "
United States
Jenniffer Gonzalez De La
The price is RM658
RM724 total
includes taxes & fees
13 Jan - 14 Jan 2026
Las Americas Golden Tower Panama

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1004)
Located near Iglesia del Carmen Station, this hotel offers an outdoor pool, steam room, and fitness centre. Enjoy meals at Cafe Ejecutivo or unwind at the bar after exploring nearby Albrook Shopping Mall and Avenida Balboa. Free breakfast, WiFi, and parking enhance your stay.

"A nice hotel to stay great location"
United States
angela
The Executive Hotel

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1456)
Immerse in Panama City at this hotel with 2 restaurants, including Martini Sushi Bar. Just steps from Avenida Balboa, guests enjoy a fitness centre, poolside bar, and casino. Free breakfast, WiFi, and valet parking enhance your stay near Albrook Shopping Mall.

"Excellent stay. Wonderful staff, good location and excellent breakfast"
United States
Michael
The price is RM560
RM616 total
includes taxes & fees
22 Dec - 23 Dec
Decapolis Hotel Panama City

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1002)
Experience Panama City in style at this luxury hotel with 4 outdoor pools, a poolside bar, and spa services. Just steps from Multiplaza Pacific Mall and Avenida Balboa, enjoy 3 restaurants, including MASI with Latin American cuisine. Free WiFi and a 24-hour fitness centre complete your stay.

"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is RM1,219
RM1,341 total
includes taxes & fees
3 Jan - 4 Jan 2026
JW Marriott Panama

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very good, (407)
Escape to this Panama City hotel with an outdoor pool and refreshing pool bar. Located near Fuerte Amador Resort, this coastal retreat offers free WiFi and parking. Albrook Shopping Mall and Cinta Costera are just a short drive away.

"Fantastic location on Amador Causeway and access to paddleboarding, restaurants, nightlife and family friendly events. One cool sloth in the tree overhanging the walkway at the Culebra nature area right by the prroperty."
United States
Cynthia
The Beach House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Las Americas Golden Tower Panama and Megapolis Hotel Panamá. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer, including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1675 hotels and other accommodation options in the surrounding area. Find out more about Santa Clara.
What should I do while I'm visiting Santa Clara?
A favourite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Clara guide.
What's the weather like in Santa Clara?
The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Santa Clara are July, August, November and October, with each month seeing an average of 283 mm of rainfall.