A beach with waves, a boat, and a forested hill in the background.

Santa Clara Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
11 Sept - 13 Sept
In two months
23 Oct - 25 Oct
In three months
20 Nov - 22 Nov
In four months
18 Dec - 20 Dec

Our top choices for Santa Clara holiday rentals

Outdoor dining

1. Refugio Frente al Mar Vista Venao

Refugio Frente al Mar Vista Venao
3.0 star property
Veracruz
9.0 out of 10, Wonderful, (2 reviews)
"The staff was very welcoming, the room was very clean and had all the commodities needed for a great experience! I highly recommend it and I'll definitely pay a second visit!"
United States
Victor
The price is RM236
RM259 total
includes taxes & fees
25 Sept - 26 Sept
Refugio Frente al Mar Vista Venao
Outdoor pool

2. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.4 out of 10, Very good, (27 reviews)
"Exactly like the photos was very nice"
Canada
Jessica
The price is RM571
RM628 total
includes taxes & fees
26 Sept - 27 Sept
Dovle Residences by HMS-Preferred Member
Interior detail

3. La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (210 reviews)
"A very helpful and friendly staff with quiet rooms that were larger than we expected. The decor was lovely and well maintained."
United States
Gabriela
The price is RM634
RM698 total
includes taxes & fees
28 Aug - 29 Aug
La Isabela Suites
Beach

4. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
3.0 star property
Vacamonte
8.4 out of 10, Very good, (5 reviews)
"Really recommended! Omar is a superhost, very helpfull and lovely! Good facilities and there is a swimmingpool and a nice little beach."
United States
Cynthia
The price is RM78
RM121 total
includes taxes & fees
1 Sept - 2 Sept
Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
Balcony

5. The Hub Modern Apartments by Wynwood

The Hub Modern Apartments by Wynwood
3.0 star property
San Francisco
The Hub Modern Apartments by Wynwood
Reception

6. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (576 reviews)
"Breakfast was great, location offered beautiful scenery with higher floor room."
United States
Solomon
The price is RM372
RM410 total
includes taxes & fees
29 Aug - 30 Aug
Torres de Alba Hotel & Suites
Front of property

7. Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (202 reviews)
"Great food and location"
United States
James
The price is RM515
RM647 total
includes taxes & fees
16 Sept - 17 Sept
Las Clementinas
Room

8. La Palma Experience

La Palma Experience
3.0 star property
Amador
8.6 out of 10, Excellent, (9 reviews)
"Air conditioner has good working. People are nice and good response for us. Basically room are clean but I can see small ants some of them on the table and on floor. I doesn't matter for it. In neighbor restaurant made big sounds at night to midnight."
Japan
Shuntaro
The price is RM391
RM431 total
includes taxes & fees
27 Sept - 28 Sept
La Palma Experience
Living area

9. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (361 reviews)
"Highly recommend..loved everything about it..will definitely be back with the whole family ❤️❤️❤️❤️"
United States
Murietta
The price is RM366
RM615 total
includes taxes & fees
14 Sept - 15 Sept
Corporate Stays Arcadia | Executive Furnished Apartments
Exterior

10. Luxury City View Apartments at Worldwide

Luxury City View Apartments at Worldwide
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (2 reviews)
"I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended."
United States
Andre
The price is RM308
RM339 total
includes taxes & fees
1 Sept - 2 Sept
Luxury City View Apartments at Worldwide
Living area

11. Modern Apartments at The Gray Prime Location

Modern Apartments at The Gray Prime Location
4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (10 reviews)
"Close to attractions and great restaurants"
United States
Tiyania
The price is RM313
RM344 total
includes taxes & fees
30 Aug - 31 Aug
Modern Apartments at The Gray Prime Location
Living area

12. La Cuadra by Wynwood House

La Cuadra by Wynwood House
3.0 star property
El Chorrillo
8.8 out of 10, Excellent, (56 reviews)
"Second stay here and just as perfect as our first stay. "
United States
G. Jeffrey
The price is RM422
RM586 total
includes taxes & fees
28 Aug - 29 Aug
La Cuadra by Wynwood House
Exterior

13. Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.0 out of 10, Very good, (130 reviews)
"Great location and very nice hotel. Great pool and restaurants."
Canada
Howard
The price is RM212
RM793 total
includes taxes & fees
31 Aug - 1 Sept
Yoo Panamá by Boutique Apartments
Pool

14. Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (105 reviews)
"Always an amazing stay"
United States
chris
The price is RM272
RM420 total
includes taxes & fees
31 Aug - 1 Sept
Casco View Apartments
Living area

15. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.6 out of 10, Good, (223 reviews)
"Great location"
United States
Hugo
The price is RM239
RM827 total
includes taxes & fees
31 Aug - 1 Sept
Boutique Apartments Panamá Coco del Mar
Pool

16. Apartments at The Sands – Ocean View Panama City

Apartments at The Sands – Ocean View Panama City
3.5 star property
Calidonia
7.8 out of 10, Good, (18 reviews)
"Property was very clean and modern."
United States
Aujae
The price is RM272
RM299 total
includes taxes & fees
30 Aug - 31 Aug
Apartments at The Sands – Ocean View Panama City
Living room

17. Cozy La Chorrera Villa With Private Patio & Nature Views

Cozy La Chorrera Villa With Private Patio & Nature Views
2.0 star property
La Chorrera
Cozy La Chorrera Villa With Private Patio & Nature Views
Living area

18. Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House
3.5 star property
Casco Viejo
9.6 out of 10, Exceptional, (16 reviews)
"Staff was courteous, and the room was very beautiful. Would stay here again!"
United States
Selam
The price is RM464
RM621 total
includes taxes & fees
28 Aug - 29 Aug
Casa Lefevre By Wynwood House
Room

19. Stylish Apartment With Pool Gym in Panama

Stylish Apartment With Pool Gym in Panama
2.0 star property
San Francisco
8.0 out of 10, Very good, (1 review)
"Would stay here again"
United States
Stepp
The price is RM518
RM708 total
includes taxes & fees
29 Aug - 30 Aug
Stylish Apartment With Pool Gym in Panama
Front of property

20. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is RM675
RM743 total
includes taxes & fees
29 Aug - 30 Aug
La Résidence Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Clara Hotel Reviews

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

10/10 Excellent
"Todo"
Walter 2-night trip
Posted less than an hour ago
Riande Aeropuerto Hotel & Casino

Find out more about Santa Clara

Search for holiday rentals in Santa Clara on Expedia.co.uk! You can easily find your home rentals, villas, holiday apartments in Santa Clara using one of the methods below:

  • View our selection of featured holiday rentals in Santa Clara
  • Use the map to find apartments and other holiday homes in the Santa Clara neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Clara while they last

Look no further and take a look at our great range of rental properties in Santa Clara!

Frequently asked questions

Can I find holiday rentals in Santa Clara?

Yes, there are holiday rentals close to the most popular sights in Santa Clara, or you can select a more secluded option if you're looking for a relaxing stay. Santa Clara is known for its monuments.

What can I see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Summit Botanical Gardens & Zoo, or get outside and enjoy nature at Culebra Cut. In the wider area, you’ll find Albrook Shopping Mall and Gamboa Rainforest Resort.

What are holiday rentals like in Santa Clara?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Clara. Holiday rentals offer extras like laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about cleanliness, holiday rentals can provide a sense of privacy away from shared hotel lifts and busy lobbies while still allowing you to travel. You'll also have more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular option for a family trip or a small group gathering.