Santa Clara Vacation Rentals

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Check prices for these dates

Tonight
30 Nov - 1 Dec
Tomorrow
1 Dec - 2 Dec
Next weekend
5 Dec - 7 Dec
In two weeks
12 Dec - 14 Dec

Vacation Rentals in Santa Clara

50-inch LED TV with satellite channels
Arcadia Condo Suites

Aparthotel in Costa del Este

2.5 star property
9.4 out of 10, Exceptional, (145)
"Wonderful place great staff "
United States
Shantia
The price is RM342
RM567 total
includes taxes & fees
1 Dec - 2 Dec
Arcadia Condo Suites
Property grounds
Swette Love 10 Minutes From the Airport Tocumen

Apartment in Las Mañanitas

2.0 star property
The price is RM240
RM312 total
includes taxes & fees
4 Dec - 5 Dec
Swette Love 10 Minutes From the Airport Tocumen
Private beach
Habitación Privada en Playa Dorada + Kitchenette

Villa in Vacamonte

3.0 star property
The price is RM99
RM153 total
includes taxes & fees
1 Dec - 2 Dec
Habitación Privada en Playa Dorada + Kitchenette
Outdoor pool
Boutique Apartments Panamá Coco del Mar

Apartment in San Francisco

3.5 star property
7.4 out of 10, Good, (150)
"Clean room good place to stay "
United States
Gideon
The price is RM214
RM815 total
includes taxes & fees
1 Dec - 2 Dec
Boutique Apartments Panamá Coco del Mar
Outdoor pool
Boutique Apartments Atlapa

Apartment in San Francisco

3.0 star property
7.8 out of 10, Good, (24)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa
Lobby sitting area
San Francisco by Wynwood House

Apartment in San Francisco

3.0 star property
9.2 out of 10, Wonderful, (53)
"This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! "
United States
mario
The price is RM408
RM552 total
includes taxes & fees
2 Dec - 3 Dec
San Francisco by Wynwood House
Outdoor pool
Living 73 Panamá by Boutique Apartments

Apartment in San Francisco

3.0 star property
The price is RM1,123
RM2,331 total
includes taxes & fees
31 Dec - 1 Jan 2026
Living 73 Panamá by Boutique Apartments
Children’s area
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Apartment in José Domingo Espinar

2.0 star property
The price is RM293
RM323 total
includes taxes & fees
7 Dec - 8 Dec
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Minibar, free WiFi
Studio Apartment with Ocean View

Apartment in Calidonia

3.0 star property
10.0 out of 10, Exceptional, (1)
"Muy amables en general "
Mexico
Algis
The price is RM269
RM295 total
includes taxes & fees
2 Dec - 3 Dec
Studio Apartment with Ocean View
Living area
Casa del Horno

Apartment in Casco Viejo

3.0 star property
7.8 out of 10, Good, (10)
"When I arrived at 3 pm no one was there! i emailed several times with no response, I tries finding a number and there was none, for the hotel or for Hotels.com"
United States
Dave
The price is RM331
RM529 total
includes taxes & fees
2 Dec - 3 Dec
Casa del Horno
Outdoor pool
Wanders Panama by Boutique Apartments

Apartment in San Francisco

4.0 star property
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
The price is RM661
RM1,359 total
includes taxes & fees
2 Dec - 3 Dec
Wanders Panama by Boutique Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Clara Hotel Reviews

The Executive Hotel

The Executive Hotel

10/10 Excellent
"Todo bien"
María 1-night trip
Posted 3 days ago
The Executive Hotel

Find out more about Santa Clara

Search for holiday rentals in Santa Clara on Expedia.co.uk! You can easily find your home rentals, villas, holiday apartments in Santa Clara using one of the methods below:

  • View our selection of featured holiday rentals in Santa Clara
  • Use the map to find apartments and other holiday homes in the Santa Clara neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Clara while they last

Look no further and take a look at our great range of rental properties in Santa Clara!

Frequently asked questions

Can I find holiday rentals in Santa Clara?

Yes, there are holiday rentals close to the most popular sights in Santa Clara, or you can select a more secluded option if you're looking for a relaxing stay. Santa Clara is known for its monuments.

What can I see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Summit Botanical Gardens & Zoo, or get outside and enjoy nature at Culebra Cut. In the wider area, you’ll find Albrook Shopping Mall and Gamboa Rainforest Resort.

What are holiday rentals like in Santa Clara?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Clara. Holiday rentals offer extras like laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about cleanliness, holiday rentals can provide a sense of privacy away from shared hotel lifts and busy lobbies while still allowing you to travel. You'll also have more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular option for a family trip or a small group gathering.