Santa Clara Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
14 Jan - 15 Jan
Tomorrow
15 Jan - 16 Jan
This weekend
16 Jan - 18 Jan
Next weekend
23 Jan - 25 Jan

Our top choices for Santa Clara holiday rentals

50-inch LED TV with satellite channels

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (192 reviews)
"Really loved this place"
United States
Alejandra
The price is RM343
RM565 total
includes taxes & fees
19 Jan - 20 Jan
Arcadia Condo Suites
Private beach

Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
3.0 star property
Vacamonte
10.0 out of 10, Exceptional, (1 review)
"The owner lives in the same compound and is so kind. He took us to the supermarket many times, let us use his washing machine and arranged a transport so we can continue our trip."
United States
Odette
The price is RM97
RM150 total
includes taxes & fees
15 Jan - 16 Jan
Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
Free WiFi, bed sheets

La Palma Aparta Suite

La Palma Aparta Suite
3.0 star property
Amador
8.0 out of 10, Very good, (3 reviews)
"All ways clean and ready to used ,no buddy "
United States
Alberto
The price is RM192
RM333 total
includes taxes & fees
15 Jan - 16 Jan
La Palma Aparta Suite
Living area

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (165 reviews)
"Love it!! Very nice!! "
United States
TEYLING
The price is RM194
RM783 total
includes taxes & fees
15 Jan - 16 Jan
Boutique Apartments Panamá Coco del Mar
Outdoor pool

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.6 out of 10, Good, (233 reviews)
"Very good value for a safe and centric location."
United States
kevin
Boutique Apartments Panama
Property grounds

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
Swette Love 10 Minutes From the Airport Tocumen
Living area

La Moderna by Wynwood House

La Moderna by Wynwood House
3.0 star property
Casco Viejo
7.4 out of 10, Good, (43 reviews)
"The nightlife around there was incredible"
United States
Felix
The price is RM241
RM399 total
includes taxes & fees
19 Jan - 20 Jan
La Moderna by Wynwood House
Outdoor pool

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
7.8 out of 10, Good, (29 reviews)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa
Reception

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (493 reviews)
"Clean room good staff and great breakfast "
United States
Gaudencio Y Mireya
Torres de Alba Hotel & Suites
Interior detail

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (174 reviews)
"Excellent place to stay in the Casco Viejo "
United States
Zoe M
La Isabela Suites
Exterior

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.4 out of 10, Very good, (53 reviews)
"Beautiful and spacious apartment with a great view and wonderful staff."
United States
Theresa
The price is RM342
RM941 total
includes taxes & fees
15 Jan - 16 Jan
Yoo Panamá by Boutique Apartments
Living area

Centriqo by Wynwood house

Centriqo by Wynwood house
3.0 star property
Veracruz
The price is RM482
RM664 total
includes taxes & fees
15 Jan - 16 Jan
Centriqo by Wynwood house
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (62 reviews)
"We live this property and stay here whenever we are in town."
United States
chris
Casco View Apartments
Pool

Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
The price is RM289
RM318 total
includes taxes & fees
15 Jan - 16 Jan
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Living area

Donovan By Wynwood House

Donovan By Wynwood House
3.0 star property
Casco Viejo
8.4 out of 10, Very good, (45 reviews)
"I always love to stay at Wynwood properties in Panama "
United States
Alberto B
The price is RM317
RM470 total
includes taxes & fees
19 Jan - 20 Jan
Donovan By Wynwood House
Restaurant

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (173 reviews)
"Fabulous room and wonderful people that work there. "
Canada
Leah
The price is RM551
RM606 total
includes taxes & fees
2 Feb - 3 Feb
Las Clementinas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Clara Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Great place to stay. Walkable area and close to restaurants, shopping and more!"
Fanny 2-night trip
Posted 11 hours ago
Hotel Riu Plaza Panama

Find out more about Santa Clara

Search for holiday rentals in Santa Clara on Expedia.co.uk! You can easily find your home rentals, villas, holiday apartments in Santa Clara using one of the methods below:

  • View our selection of featured holiday rentals in Santa Clara
  • Use the map to find apartments and other holiday homes in the Santa Clara neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Clara while they last

Look no further and take a look at our great range of rental properties in Santa Clara!

Frequently asked questions

Can I find holiday rentals in Santa Clara?

Yes, there are holiday rentals close to the most popular sights in Santa Clara, or you can select a more secluded option if you're looking for a relaxing stay. Santa Clara is known for its monuments.

What can I see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Summit Botanical Gardens & Zoo, or get outside and enjoy nature at Culebra Cut. In the wider area, you’ll find Albrook Shopping Mall and Gamboa Rainforest Resort.

What are holiday rentals like in Santa Clara?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santa Clara. Holiday rentals offer extras like laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about cleanliness, holiday rentals can provide a sense of privacy away from shared hotel lifts and busy lobbies while still allowing you to travel. You'll also have more space in a holiday rental than in a standard hotel, which makes a holiday rental a popular option for a family trip or a small group gathering.