Hotels in Santa Ana, Panama City

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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (87 reviews)
"The staff was absolutely phenomenal! So kind and accommodating even when certain events were out of their control they were still so wonderful!"
United States
Nicole
The price is RM394
RM553 total
includes taxes & fees
15 Apr - 16 Apr
Casco View Apartments

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.2 out of 10, Good, (15 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is RM317
RM458 total
includes taxes & fees
20 Apr - 21 Apr
La Manzana by Wynwood House

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (67 reviews)
"Helpful staff, secure, close to sights"
Australia
Suzanne
The price is RM114
RM125 total
includes taxes & fees
12 Apr - 13 Apr
Hostal La Cigarra

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is RM146
RM161 total
includes taxes & fees
12 Apr - 13 Apr
ART CASCO The Hotel

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (189 reviews)
"It's meant for a short stay, close to Casco Viejo and coast line. Clean bed and bathroom. Needs some maintenance. Beware, there's no hot water if that's a deal breaker for you."
United States
Mario
The price is RM116
RM128 total
includes taxes & fees
12 Apr - 13 Apr
Hotel República

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,508 reviews)
"Very clean and comfortable stay, beautiful lobby and restaurant."
United States
EL Heru
The price is RM504
RM580 total
includes taxes & fees
5 May - 6 May
Crowne Plaza Panama Airport by IHG

Villa Caprichosa

Villa Caprichosa
3.0 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (63 reviews)
"Would definitely visit again "
United States
John
The price is RM892
RM981 total
includes taxes & fees
1 May - 2 May
Villa Caprichosa

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,281 reviews)
"Great place to stay, great staff, I had a good time in the hotel itself "
United States
Walana
The price is RM575
RM632 total
includes taxes & fees
5 May - 6 May
Hotel Riu Plaza Panama

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (99 reviews)
"Great place to stay with plenty of places nearby for food and drinks"
United States
Thomas
The price is RM476
RM618 total
includes taxes & fees
12 Apr - 13 Apr
ORHO HOTEL BOUTIQUE PANAMA Airport

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,858 reviews)
"Property was good, would stay there again. "
United States
Juan
The price is RM536
RM589 total
includes taxes & fees
12 Apr - 13 Apr
Riande Aeropuerto Hotel & Casino

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (685 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is RM1,068
RM1,174 total
includes taxes & fees
2 May - 3 May
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,008 reviews)
"Nice hotel will visit again"
United States
Deisha
The price is RM401
RM441 total
includes taxes & fees
9 May - 10 May
Courtyard by Marriott Panama Metromall

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 10.2 km from Santa Ana
9.4 out of 10, Exceptional, (262 reviews)
"All units are very well equipped with everything that travelers will need. Comfortable and well located, easy access and safe neighborhood. "
United States
Jaime
The price is RM476
RM707 total
includes taxes & fees
16 Apr - 17 Apr
Arcadia Condo Suites

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 9.4 km from Santa Ana
9.0 out of 10, Wonderful, (328 reviews)
"Clean room, helpful staff, good breakfast."
United States
Stephanie
The price is RM849
RM934 total
includes taxes & fees
2 May - 3 May
The Westin Panama

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Campo Alegre, 3.3 km from Santa Ana
9.6 out of 10, Exceptional, (256 reviews)
"Great staff and the food was amazing. "
United States
Nyrisha
The price is RM625
RM687 total
includes taxes & fees
1 May - 2 May
Hyatt Regency Panama City

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 5.7 km from Santa Ana
8.6 out of 10, Excellent, (1,004 reviews)
"Breakfast was great , clean room and staff was nice "
United States
Pauline
The price is RM502
RM552 total
includes taxes & fees
1 May - 2 May
Sheraton Grand Panama

Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
San Felipe, 1.1 km from Santa Ana
9.4 out of 10, Exceptional, (16 reviews)
"What a special place! Very reasonable rate for an amazing location. 2 level suite was sweet! Love the decor. The staff and restuarant/bar is magnificent in every way!"
United States
Anonymous traveller
The price is RM485
RM533 total
includes taxes & fees
3 May - 4 May
Hotel Bardot Boutique

JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 4.3 km from Santa Ana
9.0 out of 10, Wonderful, (1,020 reviews)
"Very enjoyable stay"
Canada
Lynnette
The price is RM1,012
RM1,113 total
includes taxes & fees
2 May - 3 May
JW Marriott Panama

Hotel Plaza Herrera

Hotel Plaza Herrera
4.0 star property
San Felipe, 0.7 km from Santa Ana
9.8 out of 10, Exceptional, (36 reviews)
"Great location in walkable area of Casco Viejo. Helpful staff."
United States
Sharon
The price is RM1,081
RM1,190 total
includes taxes & fees
13 Apr - 14 Apr
Hotel Plaza Herrera

Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (346 reviews)
"I really enjoyed my stay here. The location was great and the staff is outstanding. "
Mexico
Michael
The price is RM479
RM527 total
includes taxes & fees
4 May - 5 May
Hotel San Felipe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
87 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
67 reviews
View
Iron/ironing board, free WiFi, bed sheets
La Manzana by Wynwood House
3.0 star property
7.2
Good
15 reviews
View
View from room
Hotel República
2.0 star property
6.6
189 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 93 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.