Hotels in Sanctuary, Sanibel

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Our top choices for Sanctuary hotels

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
21.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,435 reviews)
"Wonderful vacation spot for couples or family. "
United States
Scott
The price is RM668
RM833 total
includes taxes & fees
18 May - 19 May
Lani Kai Beachfront Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,834 reviews)
"Great restaurant and beach bar on premises. "
United States
Bruce
The price is RM909
RM1,112 total
includes taxes & fees
17 May - 18 May
Sanibel Island Beach Resort

Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
20.9 km from Sanctuary
9.4 out of 10, Exceptional, (1,002 reviews)
"Free breakfast, clean room, beach view, chill parrot"
United States
Katie Ann
The price is RM1,142
RM1,274 total
includes taxes & fees
30 Apr - 1 May
Best Western Plus Beach Resort

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
20.4 km from Sanctuary
9.4 out of 10, Exceptional, (1,332 reviews)
"Great spot can’t wait to come back! "
United States
DANE
Pink Shell Beach Resort and Marina

Shalimar Beach Resort

Shalimar Beach Resort
2.0 star property
West End, 10.3 km from Sanctuary
9.8 out of 10, Exceptional, (48 reviews)
"Fantastic location, updated, clean and spacious rooms."
United States
Keith
The price is RM1,617
RM1,802 total
includes taxes & fees
4 May - 5 May
Shalimar Beach Resort

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 12.8 km from Sanctuary
8.6 out of 10, Excellent, (2,636 reviews)
"Everything was fantastic! The amenities and staff were great. The breakfast is a bit pricey, but you can cook in your room if need be. "
United States
Haley
The price is RM1,775
RM2,195 total
includes taxes & fees
13 May - 14 May
Sundial Beach Resort & Spa

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
27.3 km from Sanctuary
9.2 out of 10, Wonderful, (1,002 reviews)
"Love this place!!"
United States
Teneille
The price is RM640
RM1,997 total
includes taxes & fees
5 May - 6 May
Pointe Estero Beach Resort

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
22 km from Sanctuary
8.6 out of 10, Excellent, (1,008 reviews)
"Place is quiet and right down the street from the beach"
United States
Bryan
The price is RM401
RM447 total
includes taxes & fees
3 May - 4 May
Latitude 26 Waterfront Resort & Marina

Sanibel Inn

Sanibel Inn
3.0 star property
East End, 13.8 km from Sanctuary
9.2 out of 10, Wonderful, (1,001 reviews)
"Beautiful rooms, fantastic beach access. "
United States
Brenda
The price is RM1,576
RM2,008 total
includes taxes & fees
12 May - 13 May
Sanibel Inn

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 12.8 km from Sanctuary
10.0 out of 10, Exceptional, (29 reviews)
"The property was beautiful, everything was in perfect condition, would definitely go back!!"
United States
Jennifer
The price is RM1,082
RM1,266 total
includes taxes & fees
29 Apr - 30 Apr
The Anchor Inn

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
23.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,004 reviews)
"Great place, good location "
United States
Christy
The price is RM368
RM410 total
includes taxes & fees
21 May - 22 May
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
21.8 km from Sanctuary
7.6 out of 10, Good, (395 reviews)
"Excellent. We just enjoy so much !!Rooms very clean and just across de beach !!"
United States
Marie
The price is RM510
RM657 total
includes taxes & fees
7 May - 8 May
The Bay Inn at Lani Kai

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
19.9 km from Sanctuary
8.2 out of 10, Very good, (1,128 reviews)
"Clean room, nice pool, near beaches, good breakfast."
United States
Kenneth
The price is RM317
RM353 total
includes taxes & fees
24 May - 25 May
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.8 out of 10, Excellent, (1,006 reviews)
"Loved having two bedrooms, two bathrooms, and a full sized refrigerator. Breakfast was fantastic! Lots of choices!"
United States
Sheila Margaret
The price is RM407
RM454 total
includes taxes & fees
29 Apr - 30 Apr
Residence Inn by Marriott Fort Myers Sanibel

1 Island Hideaway

1 Island Hideaway
3.0 star property
24.3 km from Sanctuary
8.6 out of 10, Excellent, (32 reviews)
"Clean and modern apartment and we stayed on first floor. Walking distance to beach with hot tub and pool. Not really walking distance to bars/restaurants so probably best to have a car. Worth the price."
United States
Howard
The price is RM787
RM1,754 total
includes taxes & fees
5 May - 6 May
1 Island Hideaway

Angler's Inn

Angler's Inn
2.5 star property
18.8 km from Sanctuary
9.4 out of 10, Exceptional, (329 reviews)
"Great location and close to lots of restaurants. Jeannette is a great host. Love this place an will stay again "
United States
Cindy
The price is RM613
RM683 total
includes taxes & fees
2 May - 3 May
Angler's Inn

DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
22.3 km from Sanctuary
9.2 out of 10, Wonderful, (1,149 reviews)
"Excellent stay, pool and room was great."
United States
Judy
The price is RM856
RM1,109 total
includes taxes & fees
4 May - 5 May
DiamondHead Beach Resort

Driftwood Inn

Driftwood Inn
2.0 star property
Mid Island, 13.1 km from Sanctuary
10.0 out of 10, Exceptional, (9 reviews)
"This was the perfect cottage for my family of 4 to spread out and not be on top of each other like a hotel room. We used the provided bikes every morning. Loved biking. The proximity to the beach with the provided umbrella, chairs, towels and wagon was awesome. Loved our stay!"
United States
Tracy
The price is RM1,198
RM2,284 total
includes taxes & fees
6 May - 7 May
Driftwood Inn

The Palmetto Inn

The Palmetto Inn
3.0 star property
31.2 km from Sanctuary
8.2 out of 10, Very good, (117 reviews)
"Wonderful location in the center of Boca Grande. Easy walk to beachside. "
United States
Maria
The price is RM694
RM774 total
includes taxes & fees
6 May - 7 May
The Palmetto Inn

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
21.5 km from Sanctuary
8.8 out of 10, Excellent, (1,007 reviews)
"Amazing place to stay! "
United States
Kristen
The price is RM494
RM551 total
includes taxes & fees
3 May - 4 May
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 9 hotels and other accommodation options in Sanctuary.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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