San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
La entrada a la Ciudad de Panamá
Edificio el tornillo

Popular places to visit

Things to do


Top hotels in San Francisco

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is RM522 per night from 8 Mar to 9 Mar
RM522
RM574 total
8 Mar - 9 Mar
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,002 reviews)
Nice staff and everything was great.

Reviewed on 27 Feb 2026

Sheraton Grand Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is RM660 per night from 26 Mar to 27 Mar
RM660
RM726 total
26 Mar - 27 Mar
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,000 reviews)
very friendly staff, amicable, attentive...I love it

Reviewed on 25 Feb 2026

Las Americas Golden Tower Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is RM1,086 per night from 8 Mar to 9 Mar
RM1,086
RM1,195 total
8 Mar - 9 Mar
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,001 reviews)
Great breakfast, service cleanliness.

Reviewed on 21 Feb 2026

JW Marriott Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
The price is RM540 per night from 2 Mar to 3 Mar
RM540
RM594 total
2 Mar - 3 Mar
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff in their ...
8.6/10 Excellent! (1,580 reviews)
Wow! Nicest hotel at. Great price. Good food and great spa too!

Reviewed on 28 Feb 2026

Decapolis Hotel Panama City
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is RM460 per night from 28 Mar to 29 Mar
RM460
RM506 total
28 Mar - 29 Mar
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. ...
9/10 Wonderful! (1,007 reviews)
Everything was great

Reviewed on 25 Feb 2026

Courtyard by Marriott Panama Multiplaza Mall
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is RM420 per night from 26 Mar to 27 Mar
RM420
RM462 total
26 Mar - 27 Mar
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool in their ...
9.4/10 Exceptional! (2,128 reviews)
the staff of the hotel thretend me to call the police for vaping, i had no idea it was prohibited even in open areas, very very rude, did not even asked me once politely

Reviewed on 26 Feb 2026

Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

Bella Vista
Aerial view of the city skyline of Panama City business district

Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


San Francisco