San Francisco

Panama City

Photo by Hideki Yamagata
Photo by ‎James Barrow
Photo by Adrian Damian
Photo by Nóra Széll
Photo by Panama Roadrunner

Popular places to visit

Things to do


Top hotels in San Francisco

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is RM564 per night from 14 Oct to 15 Oct
RM564
RM621 total
14 Oct - 15 Oct
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (954 reviews)
"Enjoyed my stay. Especially loved the gym. I will be back."

Reviewed on 27 Sept 2025

Sheraton Grand Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
The price is RM543 per night from 24 Oct to 25 Oct
RM543
RM597 total
24 Oct - 25 Oct
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (1,101 reviews)
"Very good conditions and very nice breakfast. Staff kind and clean property."

Reviewed on 27 Sept 2025

Megapolis Hotel Panamá
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is RM926 per night from 17 Oct to 18 Oct
RM926
RM1,019 total
17 Oct - 18 Oct
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff and the property condition ...
8.8/10 Excellent! (1,014 reviews)
"Property of HUGE"

Reviewed on 27 Sept 2025

JW Marriott Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
The price is RM357 per night from 24 Oct to 25 Oct
RM357
RM392 total
24 Oct - 25 Oct
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,343 reviews)
"Nice breakfast"

Reviewed on 26 Sept 2025

Decapolis Hotel Panama City
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
The price is RM458 per night from 4 Oct to 5 Oct
RM458
RM503 total
4 Oct - 5 Oct
includes taxes & fees
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,060 reviews)
"Had a great time. Staff were friendly, breakfast was good. My only issue was the absence of a bellhop. Room service daily, great view from your room and hallway. Very close to Multiplaza Mall, Burger King, Popeyes and other food establishments. Would definitely stay here again."

Reviewed on 26 Sept 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
The price is RM635 per night from 5 Oct to 6 Oct
RM635
RM699 total
5 Oct - 6 Oct
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (2,127 reviews)
"Room was very clean, staff was pleasant and helpful will definitely stay again on my trip to Panama"

Reviewed on 25 Sept 2025

Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

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Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
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Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
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Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
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Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
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Pueblo Nuevo

While there might not be top attractions in Pueblo Nuevo, you can explore the larger area and discover places like El Dorado Mall and Multiplaza Pacific Mall.

Pueblo Nuevo
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El Cangrejo

4/5(5 area reviews)

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

El Cangrejo


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