Otay Mesa
San Diego
Visit Otay Mesa
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and entertainment choices.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Things to do
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Top hotels in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
"I've stayed here many times, and my coworkers all seem to have the same complaint: the hotel doesn't appear to invest enough in maintenance and upgrades. Many rooms have old refrigerators that make a lot of noise, and most of the bathroom toilets are very outdated. In some rooms, the toilet keeps ..."
Reviewed on 24 Jun 2026
Manchester Grand Hyatt San Diego
"There was only one of two pools available"
Reviewed on 23 Jun 2026
Wyndham San Diego Bayside
"This hotel is showing its age and smelled "musty." It clearly used to be very nice but is showing the signs of it being a while since it was built. Overall, a decent place to stay at a reasonable price point. The airport shuttle is a great amenity and the onsite restaurants were very good."
Reviewed on 23 Jun 2026
Paradise Point Resort & Spa
"Wonderful stay. The location was excellent, and the on site restaurants were a great convenience with good food and plenty of options. The staff was friendly, accommodating, and helpful throughout my stay. I would definitely return and recommend this property to others."
Reviewed on 23 Jun 2026
Hard Rock Hotel San Diego
"Everything was amazing & I will be back soon!! Thank you guys for everything & making everything simple & just absolutely wonderful. Staff was friendly & helpful"
Reviewed on 24 Jun 2026
Bahia Resort Hotel
"The room was clean and comfortable, the staff were helpful when checking in. The pool was a great amenity. The beach was right there to enjoy no matter where the room was at. Had restaurants on premises"
Reviewed on 23 Jun 2026
Where to stay in Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
