Hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, 1882, (1,882 reviews)
"Good hotel for the area, can’t go wrong with a holiday inn express."
Kuljit
The price is RM558
RM634 total
includes taxes & fees
12 Oct - 13 Oct
2. Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,009 reviews)
"Very quiet and friendly staff excellent breakfast"
Mia
The price is RM430
RM489 total
includes taxes & fees
11 Oct - 12 Oct
3. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista6.5 km from Otay Mesa
9.8 out of 10, 1068, (1,068 reviews)
"We love this hotel: all the staff are very nice and helpful."
Shan Shan
The price is RM784
RM864 total
includes taxes & fees
11 Oct - 12 Oct
4. Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, 1367, (1,367 reviews)
"Great stay"
Luis
The price is RM462
RM526 total
includes taxes & fees
20 Sept - 21 Sept
5. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, 1661, (1,661 reviews)
"Great hotel to stay."
Katsuya
The price is RM438
RM482 total
includes taxes & fees
11 Oct - 12 Oct
6. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, 1534, (1,534 reviews)
"Enjoyed my stay"
Cathie
The price is RM588
RM647 total
includes taxes & fees
11 Oct - 12 Oct
7. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,744 reviews)
"Nice Breakfast selection"
Kaye
The price is RM419
RM461 total
includes taxes & fees
11 Oct - 12 Oct
8. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, 4122, (4,122 reviews)
"Great place to stay, very clean and comfortable beds."
Alexander
The price is RM656
RM723 total
includes taxes & fees
20 Sept - 21 Sept
9. SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (774 reviews)
"Clean room, great breakfast and pool, friendly and accommodating staff"
Andren
The price is RM767
RM845 total
includes taxes & fees
11 Oct - 12 Oct
10. Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique13.6 km from Otay Mesa
8.8 out of 10, 1518, (1,518 reviews)
"Great location, affordable and clean"
Sarina
The price is RM403
RM444 total
includes taxes & fees
27 Sept - 28 Sept
11. The Rambler Hotel
The Rambler Hotel14.8 km from Otay Mesa
9.0 out of 10, 2215, (2,215 reviews)
"The room was very clean, comfortable and quiet. Hotel was a quick drive to balboa park area"
debra
The price is RM484
RM560 total
includes taxes & fees
5 Oct - 6 Oct
12. Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista14.4 km from Otay Mesa
7.4 out of 10, 2316, (2,316 reviews)
"Great place to stay and very convenient"
Idanesha
The price is RM279
RM306 total
includes taxes & fees
15 Sept - 16 Sept
13. Howard Johnson by Wyndham National City/San Diego South
Howard Johnson by Wyndham National City/San Diego South18.3 km from Otay Mesa
7.6 out of 10, 1128, (1,128 reviews)
"Great hotel"
Erika
The price is RM304
RM335 total
includes taxes & fees
1 Oct - 2 Oct
14. Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU24.4 km from Otay Mesa
9.0 out of 10, 1430, (1,430 reviews)
"Great stay"
Bernadette
The price is RM534
RM602 total
includes taxes & fees
7 Oct - 8 Oct
15. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, 1719, (1,719 reviews)
"Loved the staff and location."
David
The price is RM764
RM879 total
includes taxes & fees
28 Sept - 29 Sept
16. Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,087 reviews)
"Amazing stay."
Faleoalii Iereneo
The price is RM586
RM674 total
includes taxes & fees
23 Sept - 24 Sept
17. Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.6 out of 10, 3700, (3,700 reviews)
"Beautiful resort."
Rosemarie
The price is RM688
RM997 total
includes taxes & fees
27 Sept - 28 Sept
18. Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego24.6 km from Otay Mesa
8.4 out of 10, 1005, (1,005 reviews)
"Loved the Jacuzzi, over hotel was very clean"
Tabita
The price is RM550
RM605 total
includes taxes & fees
20 Sept - 21 Sept
19. Old Town Inn
Old Town Inn30.1 km from Otay Mesa
9.0 out of 10, 1974, (1,974 reviews)
"Great place to stay!!!"
Layne
The price is RM607
RM697 total
includes taxes & fees
15 Sept - 16 Sept
20. Lafayette Hotel & Club
Lafayette Hotel & Club26.8 km from Otay Mesa
9.4 out of 10, Exceptional, (1,989 reviews)
"Amazing hotel! Will for sure be staying here again!"
Bryanna
The price is RM1,103
RM1,268 total
includes taxes & fees
22 Sept - 23 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
Top Otay Mesa Hotel Reviews
The Alcala Hotel Mission Valley/Seaworld
10/10 Excellent
