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Hotels in San Antonio, Cali

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Our top choices for San Antonio hotels

La posada del ceramista

La posada del ceramista
3.0 star property
San Antonio
The price is RM149
RM149 total
22 Dec - 23 Dec
La posada del ceramista

Casa Ruta Sur

Casa Ruta Sur
3.0 star property
San Antonio
9.8 out of 10, Exceptional, (30)
"Loved the neighborhood that this property was in. It was so pretty with lots and lots of great restaurants nearby and pretty safe. The property itself was also beautiful "
United States
Toni
The price is RM253
RM253 total
22 Dec - 23 Dec
Casa Ruta Sur

Santiago DC Hotel

Santiago DC Hotel
3.0 star property
San Antonio
8.0 out of 10, Very good, (2)
"The staff is very courteous. The breakfast is simple but delicious . The room was clean, spacious and with excellent AC. The only thing to consider is that there is a very cannabis friendly bar downstairs in the lobby area and you walk through it to get to your room. The rooms do not smell of cannabis but you walk through a lot of it. "
United States
Eva
The price is RM202
RM610 total
2 Jan - 3 Jan 2026
Santiago DC Hotel

Magic Garden House

Magic Garden House
3.0 star property
San Antonio
10.0 out of 10, Exceptional, (35)
"Very nice accommodation, great service and good location"
Germany
Klemens
Magic Garden House

Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (200)
"Rooms are spacious and beautifully designed."
United States
Mark
The price is RM399
RM475 total
13 Jan - 14 Jan 2026
Alko Hotel Casa Nispero

Hotel Casa Bresse

Hotel Casa Bresse
2.5 star property
San Antonio
10.0 out of 10, Exceptional, (3)
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Canada
Stanislaw
The price is RM128
RM128 total
2 Jan - 3 Jan 2026
Hotel Casa Bresse

San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (64)
"The staff was great. "
United States
Victor
The price is RM218
RM282 total
7 Jan - 8 Jan 2026
San Antonio Hotel Boutique

casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
The price is RM82
RM98 total
30 Dec - 31 Dec
casa hostal ave maria san antonio cali

Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
The price is RM75
RM75 total
22 Dec - 23 Dec
Epifania Guest House

Hotel Campestre Rancho La Lechería

Hotel Campestre Rancho La Lechería
3.5 star property
11.4 km from San Antonio
Hotel Campestre Rancho La Lechería

Osve Hotel Boutique

Osve Hotel Boutique
4.0 star property
1.3 km from San Antonio
10.0 out of 10, Exceptional, (2)
"Everything was good. The room, breakfast, the swimming pool..."
Belgium
Katia
The price is RM337
RM337 total
22 Dec - 23 Dec
Osve Hotel Boutique

Hotel Marrakech Cali

Hotel Marrakech Cali
3.0 star property
5.6 km from San Antonio
The price is RM234
RM234 total
31 Dec - 1 Jan 2026
Hotel Marrakech Cali

HOTEL HYM SAS

HOTEL HYM SAS
2.5 star property
27.6 km from San Antonio
8.8 out of 10, Excellent, (3)
"Staff was friendly. The towels and linens were a bit dingy and the check in counter had a musty smell and a little disorganized. "
United States
Lucy
The price is RM293
RM293 total
22 Dec - 23 Dec
HOTEL HYM SAS

Alojamientos Sucursal Cali

Alojamientos Sucursal Cali
4.0 star property
3.3 km from San Antonio
The price is RM71
RM71 total
22 Dec - 23 Dec
Alojamientos Sucursal Cali

Hotel Thama Palmira

Hotel Thama Palmira
3.0 star property
28 km from San Antonio
8.2 out of 10, Very good, (91)
"Everything was fine "
United States
Gary
The price is RM199
RM199 total
25 Dec - 26 Dec
Hotel Thama Palmira

Mirago Hotel

Mirago Hotel
2.5 star property
6 km from San Antonio
10.0 out of 10, Exceptional, (1)
"Excelente todo!"
Colombia
Michael
The price is RM204
RM204 total
5 Jan - 6 Jan 2026
Mirago Hotel

Basic Hotel Chipichape By Hoteles MS

Basic Hotel Chipichape By Hoteles MS
3.0 star property
2.9 km from San Antonio
7.0 out of 10, Good, (2)
"El desayunp adecuado "
Colombia
VLADIMIR
The price is RM168
RM168 total
1 Jan - 2 Jan 2026
Basic Hotel Chipichape By Hoteles MS

Hotel Casa Kreenty

Hotel Casa Kreenty
3.0 star property
Viejo San Fernando, 1.3 km from San Antonio
The price is RM201
RM233 total
22 Dec - 23 Dec
Hotel Casa Kreenty

Leclerc Hotel Boutique Granada

Leclerc Hotel Boutique Granada
3.5 star property
Juanambú, 1.1 km from San Antonio
9.2 out of 10, Wonderful, (35)
"Great location , Beautiful decoration, Very nice breakfast, And lovely people attending the hotel. Thank you Alan, and Miguel Angel ❤️"
United States
maritza
Leclerc Hotel Boutique Granada

Hotel Boutique Villa Casuarinas

Hotel Boutique Villa Casuarinas
3.5 star property
Ciudad Jardín, 9.4 km from San Antonio
9.8 out of 10, Exceptional, (38)
"It's a dream property in the best neighborhood of Cali. The staff are incredible friendly and helpful with all that you need. An incredible pool, a tennis court, a waterfall, all in the middle of nature with amazing trees. You can order to the pool from a Peruvian restaurant that serves amazing food. They also have spa. "
United States
Jorge
The price is RM283
RM283 total
22 Dec - 23 Dec
Hotel Boutique Villa Casuarinas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Antonio

Find the best San Antonio areas for the activities you enjoy most.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

El Peñon

While El Peñon may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Centenario Commercial Center and Rock Park.

Pance

While Pance may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Chorrera del Indio and Los Arrayanes Recreational Center.

Top San Antonio Hotel Reviews

Frequently asked questions

What's it like in San Antonio?
Travellers to the San Antonio neighbourhood in Cali will be sure to enjoy their stay.
What's the best accommodation in San Antonio?
Based on Expedia customer reviews, Alko Hotel Casa Nispero is the highest ranked property in San Antonio. This hotel offers free breakfast and a restaurant. Another favourite option in the neighbourhood is Viajero Cali Hostel & Salsa School.
How many hotels will I be able to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 45 San Antonio hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the top deals on offer in San Antonio.
What can I see and do in this Cali neighbourhood?
Religious Art Museum, Enrique Buenaventura Municipal Theater and La Merced Archaeological Museum are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Calima Gold Museum of the Bank of the Republic and Comfandi and Comfenalco Cultural Center are a couple of additional sights to visit in Cali.