𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Perryville from RM275 (2026) - Fully Refundable Options

A train crossing a stone bridge over a river, surrounded by lush greenery.

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Our top choices for Perryville hotels

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A Holiday Inn Express & Suites building with a covered entrance and multiple windows.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.

A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

1. Holiday Inn Express & Suites Perryville by IHG

Perryville

Kristen

RM390

RM447 total

includes taxes & fees

3 Sept - 4 Sept

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

2. Super 8 by Wyndham Perryville

Perryville

Elizabeth

RM274

RM313 total

includes taxes & fees

15 Sept - 16 Sept

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

3. Perryville RV Resort

Perryville

Von

RM267

RM306 total

includes taxes & fees

31 Aug - 1 Sept

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A building with a sign that reads "The Atrium Boutique Hotel".

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

4. The Atrium - A Boutique Hotel

Perryville

Brian

RM304

RM642 total

includes taxes & fees

31 Aug - 1 Sept

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A swimming pool with a metal ladder, a Days Inn sign, and a blue water tower in the background.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

A hotel hallway with a patterned carpet, blue walls, and a sign indicating an office.

5. Days Inn by Wyndham Perryville

Perryville

Wanda

RM287

RM328 total

includes taxes & fees

31 Aug - 1 Sept

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A breakfast bar with a toaster, coffee maker, and fruit juice dispenser.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

A hotel room with a desk, a television, a coffee maker, a chair, and a window with curtains.

6. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

RM271

RM311 total

includes taxes & fees

3 Sept - 4 Sept

A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

A two-story building with a balcony, a front door with a wreath, and a sign indicating a restaurant.

A kitchen with a large black sink, a window with a view of trees, and a microwave on the counter.

A wooden interior with a dining area, staircase, and a television mounted on the wall.

7. The Mediterranean House 1858

Perryville

RM2,025

RM3,287 total

includes taxes & fees

31 Aug - 1 Sept

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A spacious living area with a large window, a ceiling fan, and a kitchen area with modern appliances.

8. Urban Lofts

Perryville

Grace

RM811

RM1,252 total

includes taxes & fees

31 Aug - 1 Sept

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

A hotel room with two beds, a brick wall, and a wooden headboard.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

9. Drury Inn & Suites Jackson MO

Jackson

Jamie

RM342

RM362 total

includes taxes & fees

22 Sept - 23 Sept

A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

A modern bathroom with a large bathtub, a wooden floor, and a dark wall with a colorful abstract painting.

A room with a fireplace, a mounted deer head, a bookshelf, and two armchairs.

A gym with treadmills, a weight machine, and exercise balls.

10. Baymont by Wyndham Chester IL

Chester

Keng

RM344

RM382 total

includes taxes & fees

15 Sept - 16 Sept

A hot tub area with a view of the parking lot through a glass door.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.

A large brick building with a central entrance flanked by columns, likely a hotel or office building.

11. Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

Keisha

RM407

RM451 total

includes taxes & fees

4 Sept - 5 Sept

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

12. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Shawn

RM373

RM404 total

includes taxes & fees

1 Sept - 2 Sept

A row of single-story houses with attached garages, a paved driveway, and a clear sky.

A modern living room with a flat-screen TV, a desk with a computer, two armchairs, a coffee table, and large windows with a view.

A reception desk with a digital map of the USA, a wooden reception area, and a sign for 'MICROHOTEL BY JYNDHAMI'.

A hotel room with two beds, a desk, a chair, and a window with curtains.

13. Microtel Inn & Suites by Wyndham Sainte Genevieve

Ste Genevieve

Samantha

RM363

RM427 total

includes taxes & fees

6 Sept - 7 Sept

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

14. Tru By Hilton Cape Girardeau

Cape Girardeau

Darlene

RM360

RM409 total

includes taxes & fees

6 Sept - 7 Sept

A building with a stone facade, a yellow door, a green chair, and a potted plant.

A compact kitchen with black cabinets, a black refrigerator, a microwave, and a sink.

A parking lot with a sign for Triangle Inn.

15. Triangle Inn Motel

Ste Genevieve

rocky

RM277

RM326 total

includes taxes & fees

31 Aug - 1 Sept

A motel with a covered entrance, a flag, and a phone number.

A spacious kitchen with a dining area, featuring a ceiling fan, a TV mounted on the wall, and a large rug in the center.

A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.

A living room with a black leather sofa, a wooden coffee table with a vase of flowers, a green potted plant, and a lamp.

16. Madison Inn Lodge

Fredericktown

Melissa

RM352

RM385 total

includes taxes & fees

8 Sept - 9 Sept

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

17. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

RM322

RM348 total

includes taxes & fees

20 Sept - 21 Sept

A large, two-story house with a wrap-around porch and a central tower.

A room with a red velvet sofa, a chandelier, a mirror, and a vanity with a sink.

A four-poster canopy bed with a wooden headboard, a chandelier, and a radiator on the floor.

A covered patio with a picnic table, surrounded by a brick pathway and greenery.

18. The Conner House B&B

Prairie du Rocher

James

RM629

RM698 total

includes taxes & fees

31 Aug - 1 Sept

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

19. Town House Inn

Jackson

Taylor

RM254

RM275 total

includes taxes & fees

31 Aug - 1 Sept

A modern bedroom with a large bed, a desk with a computer, a chair, and a window with a view of a lake.

A motel with a blue exterior, a central garage entrance, and a parking lot with several cars.

A grassy field with a small building, a fenced area, and a few vehicles.

20. Briarwood Inn of Sparta

Sparta

Steve

RM358

RM398 total

includes taxes & fees

31 Aug - 1 Sept

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Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

8.8/10 (19 reviews)

This serene Catholic shrine honours the Miraculous Medal with exquisite stained glass and intricate murals. Visitors find spiritual renewal along the peaceful Rosary Walk and Marian Grotto gardens.

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Saint Marys Lake

Saint Marys Lake offers a tranquil escape in Missouri's countryside with serene waters reflecting the changing seasons. Bring a picnic and binoculars to spot local wildlife while enjoying this peaceful local reservoir.

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County Lake State Wildlife Management Area

This peaceful 103-acre reservoir offers exceptional fishing for largemouth bass, bluegill, and hybrid striped bass. Cast your line near brush piles and vegetation beds for the best chance at a memorable catch.

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Perryville Country Club

6.6/10 (7 reviews)

This classic 9-hole course features Zoysia fairways and Bent grass greens dating back to 1932. Enjoy a challenging round followed by refreshments at the clubhouse overlooking the scenic Missouri landscape.

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Missouri's National Veterans Memorial

9.2/10 (14 reviews)

This full-scale replica of the Vietnam Veterans Memorial offers a profound space for reflection away from Washington D.C. Walk the black granite wall inscribed with 58,000 names in Missouri's countryside.

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Feltz Street Park

This community park features a gentle 0.41-mile loop trail and pickleball court. Bring your own equipment and enjoy this peaceful local spot during spring or fall for the best outdoor experience.

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Perryville City Hall

Perryville City Hall serves as the administrative heart of this Missouri town, housing essential government offices. Visit during weekday business hours to access city services or attend public meetings.

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James M. Eddleman Millitary Museum

This veteran-founded museum honours military service through authentic Vietnam War artefacts and personal stories. Explore Jim Eddleman's collection and experience history through the eyes of those who lived it.

See properties

Perryville and related destinations

Historic battlefields and the charming city centre district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Centre and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend.

See all hotels in Perryville

Top Perryville Hotel Reviews

Triangle Inn Motel

8/10 Good

"This is a nice small older family run roadside motel that is kept clean and perfect for a comfortable night stay … staff was polite and I’m sure we will stay again when visiting the area"

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"We had a pleasnt stay for a reasonable price. Our room was clean and quiet. The beds and pillows were comfortable. Breakfast was good with hot and cold choices. The staff was friendly and helpful."

Madison Inn Lodge

10/10 Excellent

"Great experience"

Tru By Hilton Cape Girardeau

8/10 Good

"Staff was friendly and welcoming."

Microtel Inn & Suites by Wyndham Sainte Genevieve

8/10 Good

"The Breakfast items were a bit stale. Staff was not super helpful."

Perryville RV Resort

10/10 Excellent

"Great time"

Urban Lofts

10/10 Excellent

"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."

More cheap stays in Perryville

Super 8 by Wyndham Perryville

1119 Vincent Dr Perryville MO

RM274

RM313 total

15 Sept - 16 Sept

includes taxes & fees

Baymont by Wyndham Chester IL

2150 State Street Chester IL

RM344

RM382 total

15 Sept - 16 Sept

includes taxes & fees

8.4/10 Very good! (417 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

RM360

RM409 total

6 Sept - 7 Sept

includes taxes & fees

9.6/10 Exceptional! (173 reviews)

Microtel Inn & Suites by Wyndham Sainte Genevieve

21958 Hwy 32 Ste Genevieve MO

RM363

RM427 total

6 Sept - 7 Sept

includes taxes & fees

8.8/10 Excellent! (665 reviews)

Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St Perryville MO

RM390

RM447 total

3 Sept - 4 Sept

includes taxes & fees

9.2/10 Wonderful! (619 reviews)

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

120 MUDDY MONSTER ROAD Murphysboro IL

RM447

RM496 total

28 Sept - 29 Sept

includes taxes & fees

Frequently asked questions

What's the best place for a stay in Perryville?

Holiday Inn Express & Suites Perryville by IHG is one of the top choices for your stay based on our traveller data. This hotel offers free breakfast and an indoor pool. Other good choices for your stay include Super 8 by Wyndham Perryville and Days Inn by Wyndham Perryville. See all available top hotels, or vacation rentals in Perryville.

If I need to cancel my hotel reservation in Perryville, will I receive a refund?

Yes, the majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Perryville.

What is the favourite LGBTQ-friendly accommodation in Perryville?

Holiday Inn Express & Suites Perryville by IHG is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. See all available hotels listed as LGBTQ-friendly in Perryville.

What's the best dog-friendly place to stay in Perryville?

Days Inn by Wyndham Perryville is a top hotel for people travelling with their pets, and offers a seasonal outdoor pool and laundry facilities for its human guests. Other good choices for you and your pet's trip include Super 8 by Wyndham Perryville and Perryville RV Resort. See more pet-friendly hotel accommodations in Perryville.

What are some hotels with pools in Perryville?

Quality Inn Perryville I-55 is a top hotel with a seasonal outdoor pool, free breakfast and free WiFi. View all hotels with pools in Perryville.

What is staying in Perryville like?

Visitors can enjoy all that Perryville has to offer, including the wineries, golf courses and coffee shops. Tourists can also enjoy the city's festivals, university setting and parks. In Perryville, there are 26 hotels and other accommodation options to choose from. Find out more about Perryville.

What is there to see in Perryville?

Landmarks like National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial might be worth a visit. Natural beauty is on display at Mark Twain National Forest, Mississippi River and Feltz Street Park. A couple of additional sights to add to your itinerary are Perryville City Hall and Perryville Country Club. Take a look at what more there is to see and do in Expedia's Perryville guide.

What's the seasonal weather in Perryville?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Perryville is 1219 mm.

Perryville hotels from RM275

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Perryville

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Perryville hotels

1. Holiday Inn Express & Suites Perryville by IHG

2. Super 8 by Wyndham Perryville

3. Perryville RV Resort

4. The Atrium - A Boutique Hotel

5. Days Inn by Wyndham Perryville

6. Quality Inn Perryville I-55

7. The Mediterranean House 1858

8. Urban Lofts

9. Drury Inn & Suites Jackson MO

10. Baymont by Wyndham Chester IL

11. Holiday Inn Express Hotel & Suites Sparta by IHG

12. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

13. Microtel Inn & Suites by Wyndham Sainte Genevieve

14. Tru By Hilton Cape Girardeau

15. Triangle Inn Motel

16. Madison Inn Lodge

17. Comfort Suites Jackson-Cape Girardeau

18. The Conner House B&B

19. Town House Inn

20. Briarwood Inn of Sparta

Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

Saint Marys Lake

County Lake State Wildlife Management Area

Perryville Country Club

Missouri's National Veterans Memorial

Feltz Street Park

Perryville City Hall

James M. Eddleman Millitary Museum

Perryville and related destinations

Top Perryville Hotel Reviews

Triangle Inn Motel

Holiday Inn Express & Suites Perryville by IHG

Madison Inn Lodge

Tru By Hilton Cape Girardeau

Microtel Inn & Suites by Wyndham Sainte Genevieve

Perryville RV Resort

Urban Lofts

More cheap stays in Perryville

Super 8 by Wyndham Perryville

Baymont by Wyndham Chester IL

Tru By Hilton Cape Girardeau

Microtel Inn & Suites by Wyndham Sainte Genevieve

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Frequently asked questions

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