Hotels in Midtown, St. Louis

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Sept - 28 Sept
Tomorrow
28 Sept - 29 Sept
Next weekend
3 Oct - 5 Oct
In two weeks
10 Oct - 12 Oct

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in Midtown, St. Louis

Element St. Louis Midtown
Courtyard

Element St. Louis Midtown

3.0 star property
9.0 out of 10, Wonderful, (595)
"Loved my stay! "
The price is RM570
RM667 total
includes taxes & fees
13 Oct - 14 Oct
Element St. Louis Midtown
Residence Inn by Marriott St Louis Downtown
BBQ/picnic Area

Residence Inn by Marriott St Louis Downtown

3.0 star property
7.8 out of 10, Good, (1003)
"Breakfast was wonderful, staff is amazing, wonderful stay!!"
The price is RM481
RM573 total
includes taxes & fees
12 Oct - 13 Oct
Residence Inn by Marriott St Louis Downtown
Drury Plaza Hotel St. Louis at the Arch
Rooftop terrace

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (3106)
"Great staff and food "
The price is RM507
RM592 total
includes taxes & fees
2 Oct - 3 Oct
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport
Lobby

Pear Tree Inn St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (2701)
"Nice place to stay "
The price is RM380
RM447 total
includes taxes & fees
20 Oct - 21 Oct
Pear Tree Inn St. Louis Airport
Drury Inn & Suites St. Louis Union Station
Indoor pool

Drury Inn & Suites St. Louis Union Station

3.0 star property
9.4 out of 10, Exceptional, (1260)
" Love staying here!"
The price is RM502
RM598 total
includes taxes & fees
2 Oct - 3 Oct
Drury Inn & Suites St. Louis Union Station
Hyatt Regency St. Louis at The Arch
Lobby

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very good, (4023)
"Close to all events great stay"
The price is RM528
RM622 total
includes taxes & fees
2 Oct - 3 Oct
Hyatt Regency St. Louis at The Arch
Moonrise Hotel
Exterior

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1905)
"Food on the rooftop was amazing "
The price is RM602
RM716 total
includes taxes & fees
6 Oct - 7 Oct
Moonrise Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lobby sitting area

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
8.2 out of 10, Very good, (1040)
"The staff was nice, breakfast was good, the location was convenient. "
The price is RM377
RM435 total
includes taxes & fees
29 Sept - 30 Sept
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Embassy Suites by Hilton St. Louis Downtown
Exterior

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
8.8 out of 10, Excellent, (1231)
"Clean quiet rooms and friendly staff!"
The price is RM524
RM623 total
includes taxes & fees
5 Oct - 6 Oct
Embassy Suites by Hilton St. Louis Downtown
Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2981)
"Great staff and hotel!"
The price is RM431
RM502 total
includes taxes & fees
12 Oct - 13 Oct
Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis
Interior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1390)
"Wonderful stay! "
The price is RM638
RM767 total
includes taxes & fees
30 Sept - 1 Oct
21C Museum Hotel St Louis
AC Hotel St. Louis Clayton
2 bars/lounges, rooftop bar

AC Hotel St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (187)
"Enjoyed my stay"
The price is RM587
RM684 total
includes taxes & fees
12 Oct - 13 Oct
AC Hotel St. Louis Clayton
Wingate by Wyndham St. Louis Airport
Desk, laptop workspace, iron/ironing board, free cots/infant beds

Wingate by Wyndham St. Louis Airport

2.5 star property
9.2 out of 10, Wonderful, (1430)
"Very clean and friendly staff"
The price is RM483
RM569 total
includes taxes & fees
7 Oct - 8 Oct
Wingate by Wyndham St. Louis Airport
Live by Loews - St.Louis
Breakfast, lunch and dinner served

Live by Loews - St.Louis

4.0 star property
9.2 out of 10, Wonderful, (1060)
"Great quick stay!"
The price is RM714
RM849 total
includes taxes & fees
5 Oct - 6 Oct
Live by Loews - St.Louis
Forest Park Hotel by MDR
Lobby sitting area

Forest Park Hotel by MDR

3.0 star property
7.6 out of 10, Good, (1148)
"Was a good stay "
The price is RM410
RM486 total
includes taxes & fees
29 Sept - 30 Sept
Forest Park Hotel by MDR
The West End
Terrace/patio

The West End

2.0 star property
8.4 out of 10, Very good, (319)
"Feel like home, enjoyed my stay there."
The West End
The Cheshire
Terrace/patio

The Cheshire

4.0 star property
8.6 out of 10, Excellent, (1013)
"Great staff, wonderful property."
The price is RM570
RM677 total
includes taxes & fees
12 Oct - 13 Oct
The Cheshire
Pear Tree Inn St. Louis Arnold
Lobby

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1016)
"Clean, comfortable and pleasant stay."
The price is RM380
RM439 total
includes taxes & fees
6 Oct - 7 Oct
Pear Tree Inn St. Louis Arnold
Sonesta ES Suites St. Louis - Chesterfield
Front of property

Sonesta ES Suites St. Louis - Chesterfield

3.0 star property
8.0 out of 10, Very good, (1018)
"Very nice place"
The price is RM367
RM426 total
includes taxes & fees
6 Oct - 7 Oct
Sonesta ES Suites St. Louis - Chesterfield
Drury Inn & Suites St. Louis Forest Park
Lobby

Drury Inn & Suites St. Louis Forest Park

3.0 star property
9.4 out of 10, Exceptional, (1025)
"Always a great stay "
The price is RM486
RM568 total
includes taxes & fees
5 Oct - 6 Oct
Drury Inn & Suites St. Louis Forest Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Central West End featuring heritage elements

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Lewis & Clark Boathouse and Nature Center while in the area.

Top Midtown Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Great staff and hotel!"
Astrid 1-night trip
Posted 3 days ago
Clayton Plaza Hotel & Extended Stay

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is Midtown like?

Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown.

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 29 Midtown hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.

What are the top things to see and do in Midtown?

Explore Midtown's landmarks such as Washington Avenue Historic District, Samuel Cupples House and Scott Joplin House State Historic Site and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium and Gateway Arch. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.