Midtown
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its great live music.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Best of St. Louis Small Group Tour w/ Arch & River Cruise
Dinner Detective True Crime Murder Mystery Show - St. Louis, MO
St Louis Self-Guided Driving and Walking Audio Tour
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Driving Tour with Boat Ride & Arch
Top hotels in Midtown
Element St. Louis Midtown
Great stay!
Reviewed on 23 Dec 2025
Hyatt Regency St. Louis at The Arch
The parking would have been great if it was free or had an option for free parking but overall the stay was great, business friendly and nice restaurants located within the hotel.
Reviewed on 26 Dec 2025
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Nice friendly staff. Clean, well stocked room. Fresh breakfast, nice variety of food.
Reviewed on 27 Dec 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hotel decorated beautifully for Christmas. Room was clean and well appointed. The staff were very friendly and welcoming. The ooey gooey butter cookie offered at bedtime was delicious! Will definitely stay here again!
Reviewed on 24 Dec 2025
Clayton Plaza Hotel & Extended Stay
Great hotel near downtown St Louis
Reviewed on 27 Dec 2025
21C Museum Hotel St Louis
The entire hotel was fantastic. Beautifully decorated, so much to see. The art gallery was fantastic, the servers at the bar were friendly and phenomenal and just made for a great evening. The food was fantastic. Every inch of the building was well styled and the room was fantastic. Can’t wait to ...
Reviewed on 22 Dec 2025
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
