Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
Key West Butterfly and Nature Conservatory which includes flowers, animals and zoo animals
South Beach which includes a beach and a coastal town as well as a large group of people
South Beach featuring swimming, a luxury hotel or resort and a beach
Key West Butterfly and Nature Conservatory which includes signage

Popular places to visit

Things to do


Top hotels in Uptown - Upper Duval

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
The price is RM1,439 per night from 26 Jan to 27 Jan
RM1,439
per night
26 Jan - 27 Jan
Stay at this beach hotel in Key West. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.6/10 Excellent! (2,960 reviews)
Nice clean room, scenic views, accessible area

Reviewed on 30 Dec 2025

Southernmost Beach Resort and Guesthouses
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

4 out of 5
1435 Simonton Street Key West FL
The price is RM1,328 per night from 13 Jan to 14 Jan
RM1,328
per night
13 Jan - 14 Jan
Stay at this beach resort in Key West. Enjoy a full-service spa, a private beach and breakfast (surcharge). Our guests praise the helpful staff and the property ...
8.4/10 Very Good! (1,002 reviews)
Hotel was beautiful. My view from my balcony was fantastic. The staff were really friendly

Reviewed on 26 Dec 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street Key West FL
The price is RM1,062 per night from 5 Jan to 6 Jan
RM1,062
per night
5 Jan - 6 Jan
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8.2/10 Very Good! (1,230 reviews)
This is an older hotel but it was exactly what we wanted. Quiet, clean, and close to Duval street. The jacuzzi was great as well as the heated pool. Staff was friendly. The only con I have is the breakfast variety.

Reviewed on 1 Jan 2026

The Southernmost Inn - Adults Only
Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street Key West FL
The price is RM1,020 per night from 5 Jan to 6 Jan
RM1,020
per night
5 Jan - 6 Jan
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8.6/10 Excellent! (1,253 reviews)
Perfect location. Affordable. Clean. Friendly staff.

Reviewed on 1 Jan 2026

Southwinds Motel
Douglas House

Douglas House

3 out of 5
419 Amelia St Key West FL
The price is RM992 per night from 13 Jan to 14 Jan
RM992
per night
13 Jan - 14 Jan
Stay at this 3-star guesthouse in Key West. Enjoy free Wi-Fi, free parking and daily housekeeping. Popular attractions Duval Street and Ernest Hemingway Home ...
9.6/10 Exceptional! (238 reviews)
Very clean, comfortable and courteous staff. Nice location.

Reviewed on 29 Dec 2025

Douglas House
Southernmost House

Southernmost House

4 out of 5
1400 Duval Street Key West FL
The price is RM1,677 per night from 15 Jan to 16 Jan
RM1,677
per night
15 Jan - 16 Jan
Stay at this beach hotel in Key West. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the helpful staff and the property condition in their ...
9.4/10 Exceptional! (1,000 reviews)
This property is beautiful and interesting for its rich history. The cottage rooms are right on the water. Staff is amazing and the breakfast is delicious from local bakery.

Reviewed on 27 Dec 2025

Southernmost House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

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Old Town Key West

5/5(6 area reviews)

While visiting Old Town Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.

Old Town Key West
Harry S. Truman Little White House featuring cycling and a house

Bahama Village

5/5(1 area review)

Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
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Downtown Key West

While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.

Downtown Key West
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Key West Historic District

4.5/5(66 area reviews)

Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Key West Cemetery.

Key West Historic District
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Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
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White Street Gallery District

If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Clarence S. Higgs Memorial Beach Park.

White Street Gallery District


Uptown - Upper Duval