Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
Key West Butterfly and Nature Conservatory which includes flowers, animals and zoo animals
South Beach which includes a beach and a coastal town as well as a large group of people
South Beach featuring swimming, a luxury hotel or resort and a beach
Key West Butterfly and Nature Conservatory which includes signage

Popular places to visit

Things to do


Top hotels in Uptown - Upper Duval

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
Fully refundable
The price is RM769 per night from 30 Nov to 1 Dec
RM769
RM1,171 total
30 Nov - 1 Dec
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,858 reviews)
Room was very clean the staff was friendly an helpfull

Reviewed on 5 Nov 2025

Southernmost Beach Resort and Guesthouses
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

4 out of 5
1435 Simonton Street, Key West, FL
The price is RM990 per night from 19 Nov to 20 Nov
RM990
RM1,365 total
19 Nov - 20 Nov
includes taxes & fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,000 reviews)
Out of the way of Duval to be quiet but close enough to walk and enjoy if that’s your vibe.

Reviewed on 4 Nov 2025

The Reach Key West, Curio Collection by Hilton
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street, Key West, FL
The price is RM482 per night from 12 Nov to 13 Nov
RM482
RM730 total
12 Nov - 13 Nov
includes taxes & fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,173 reviews)
Courteous staff excellent location quiet

Reviewed on 5 Nov 2025

The Southernmost Inn - Adults Only
Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street, Key West, FL
The price is RM603 per night from 18 Nov to 19 Nov
RM603
RM820 total
18 Nov - 19 Nov
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.8/10 Excellent! (1,228 reviews)
Staff was very courteous.

Reviewed on 6 Nov 2025

Southwinds Motel
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

3.5 out of 5
1004 Duval St, Key West, FL
The price is RM1,061 per night from 16 Nov to 17 Nov
RM1,061
RM1,194 total
16 Nov - 17 Nov
includes taxes & fees
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, parking (surcharge), and a 24-hour front desk. Our guests praise the breakfast and the pool in ...
9.8/10 Exceptional! (1,000 reviews)
Second year in a row we have stayed here! It’s now a tradition. Love the cozy nature. Pool is amazing. Bartenders great. Staff outstanding. Always clean. And well Mr. P is the best

Reviewed on 5 Nov 2025

Orchid Key Inn - Adults Only
Southernmost House

Southernmost House

4 out of 5
1400 Duval Street, Key West, FL
The price is RM1,199 per night from 7 Dec to 8 Dec
RM1,199
RM1,737 total
7 Dec - 8 Dec
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (999 reviews)
Great place with excellent staff.

Reviewed on 7 Nov 2025

Southernmost House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

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Old Town Key West

5/5(6 area reviews)

While visiting Old Town Key West, you might make a stop by sights like Duval Street and Saint Mary Star of the Sea.

Old Town Key West
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Downtown Key West

While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.

Downtown Key West
Harry S. Truman Little White House featuring cycling and a house

Bahama Village

5/5(1 area review)

Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
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Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
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Key West Historic District

4.5/5(66 area reviews)

Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Saint Mary Star of the Sea.

Key West Historic District
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White Street Gallery District

If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Saint Mary Star of the Sea.

White Street Gallery District


Uptown - Upper Duval