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Our top choices for Southeastern Indiana hotels

A hotel room with two beds, a TV, a desk, and a chair.

1. Comfort Inn & Suites Clarksville - Louisville North

Clarksville

Yvonne

RM477 total

includes taxes & fees

13 Dec - 14 Dec

A hotel room with two beds, a desk, a chair, a lamp, and a window with blinds.

2. Holiday Inn Express & Suites Louisville N - Jeffersonville by IHG

Jeffersonville

Michael

RM474 total

includes taxes & fees

10 Dec - 11 Dec

A vending machine with snacks and drinks, located in a hotel lobby with seating and a reception area.

3. Hampton Inn Louisville-North/Clarksville

Clarksville

Michael

RM464 total

includes taxes & fees

6 Dec - 7 Dec

A spacious living room with grey sofas, a glass coffee table, a fireplace, and a chandelier.

4. Ramada by Wyndham Sellersburg/Louisville North

Sellersburg

Michael

RM351 total

includes taxes & fees

22 Nov - 23 Nov

A modern bar area with wooden bar stools, pendant lighting, and artwork on the walls.

5. Fairfield Inn & Suites by Marriott Louisville New Albany IN

New Albany

Alaithia

RM514 total

includes taxes & fees

6 Dec - 7 Dec

A breakfast bar with a sign reading "HAPPY BREAKFAST STARTS HERE," a coffee machine, and various food items.

6. Hampton Inn New Albany Louisville West

New Albany

Wayne

RM425 total

includes taxes & fees

25 Nov - 26 Nov

An outdoor patio with a fire feature, seating, and a covered area with string lights.

7. Home2 Suites by Hilton Clarksville Louisville North

Clarksville

Tracy

RM505 total

includes taxes & fees

20 Nov - 21 Nov

A hotel room with two beds, a desk, a chair, and a nightstand with a lamp.

8. Spark by Hilton Sellersburg

Sellersburg

Charles

RM350 total

includes taxes & fees

1 Dec - 2 Dec

An indoor dining area with tables and chairs, large windows, and a brick wall.

9. Hilton Garden Inn Jeffersonville Louisville North

Jeffersonville

Tirana

RM493 total

includes taxes & fees

28 Nov - 29 Nov

A Red Roof Inn lobby with two leather armchairs, a small table, and a potted plant.

10. Red Roof Inn Georgetown, IN - Louisville West

Georgetown

Michael

RM303 total

includes taxes & fees

1 Dec - 2 Dec

A hotel room with a flat-screen TV, a desk, a sofa, a small table, and a patterned carpet.

11. Knights Inn and Suites Salem

Salem

Charles

RM345 total

includes taxes & fees

13 Nov - 14 Nov

A spacious lobby with a staircase, seating area, and a dining area.

12. Holiday Inn Express Corydon by IHG

Corydon

Tracy

RM457 total

includes taxes & fees

13 Dec - 14 Dec

A modern interior with a fireplace, wooden panel wall, bar area, and kitchen with coffee machines.

13. Hampton Inn & Suites Scottsburg

Scottsburg

Alexander

RM527 total

includes taxes & fees

20 Nov - 21 Nov

A hotel lobby with a large mural, seating area, and a reception desk.

14. Quality Inn Corydon

Corydon

Cheryl

RM341 total

includes taxes & fees

6 Dec - 7 Dec

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

15. Fairfield Inn & Suites by Marriott Louisville Jeffersonville

Jeffersonville

Sybil

RM553 total

includes taxes & fees

20 Nov - 21 Nov

16. Days Inn & Suites by Wyndham Sellersburg

Sellersburg

Brandon

RM273 total

includes taxes & fees

15 Nov - 16 Nov

A multi-story hotel with a prominent "Candlewood Suites" sign, featuring a brick facade and a central entrance with glass doors.

17. Candlewood Suites Louisville North by IHG

Clarksville

Stephanie

RM431 total

includes taxes & fees

29 Nov - 30 Nov

A covered entrance with a bench and a trash can, flanked by stone pillars and a building entrance.

18. SureStay by Best Western Salem

Salem

Victoria

RM339 total

includes taxes & fees

16 Nov - 17 Nov

A hotel room with a bed, a desk, a chair, a sofa, and a bench.

19. HavenPointe Inn & Suites

Scottsburg

Nandini

RM337 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel room with a large bed, a desk with a chair, a nightstand with a lamp, and artwork on the walls.

20. Best Western Green Tree Inn

Clarksville

Michael

RM405 total

includes taxes & fees

19 Nov - 20 Nov

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Holiday Rentals in Southeastern Indiana

Aparthotel

A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.

stayAPT Suites Louisville North-Clarksville

Clarksville

"Great option for a long term stay, good area many businesses in walking distance!"

Aparthotel

A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.

CozySuites at Nulu

Downtown Louisville

"We love staying at this location when we come to Louisville. It’s a great apartment that is conveniently located. Love the view of the Big Four Bridge at night!"

Cottage

A rustic interior with wooden beams, a stone wall, a fireplace, and a television.

French Lick Getaway w/ Deck, Grill & Fire Pit!

French Lick

"We had no problem finding the property. It was less than a 10 minute drive into town. The house had everything needed for cooking. Toilet paper, paper towels, bath towels, outdoor seating were all provided. I somehow missed when booking the house that we were bringing our small dogs and when I contacted the owner it was easily fixed. Everyone I was in contact with was pleasant to talk to. If I had anything negative it would be that the property needed some attention. We drive a truck and we had...

Aparthotel

Hawthorn Suites by Wyndham Louisville North

Jeffersonville

"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"

Cottage

A modern kitchen with granite countertops, stainless steel appliances, and dark wood cabinets.

East End River Retreat: Dogs Welcome!

Madison Historic District

"Great location. Clean great location"

Cottage

A wooden house with a porch, a garden with pumpkins, and a gravel driveway.

'the Bovard Lodge' Rustic Cabin Near Ohio River!

Florence

"The cabin was really great; clean, comfortable, private, check-in and check-out were hassle-free, communication was done via text and she was easygoing. We didn't realize the loft had a lower ceiling so our teens had to duck when walking but they could sit comfortably on the beds. Thank you for a wonderful experience!!"

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Stay near popular Southeastern Indiana attractions

A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)

Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

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Learn more about Southeastern Indiana

Explore lots to see and do in Southeastern Indiana—live music, sports teams and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards.

See all hotels in Southeastern Indiana

A riverboat with multiple decks and passengers, docked near a bridge.

Top Southeastern Indiana Hotel Reviews

The Villas at French Lick Springs

10/10 Excellent

"We were in town for the weekend and chose to stay in a villa. It was great. We had an entire 1-bedroom condo, which had a coffee maker, toaster, stove, oven, microwave and refrigerator, as well as whatever pans you needed to cook with, and dishes. There was also a washer and dryer available, which we didn't need. It was great to have the space, and for a reasonable price. It was very quiet at night, too."

Hampton Inn New Albany Louisville West

8/10 Good

"The breakfast was the best! The room was nice. This isn't a place for scenery which isn't their fault but its not somewhere to try and see the river or have scenic trees outside the window. The toliet was loud when you flushed which woke me up when my husband went to the bathroom in the middle of the night. Overall though this was a good place to stay. I felt safe and would stay here again."