Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and churches in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the notable monuments in this vibrant area.
Things to do
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
Cinque Terre and Pisa Day Trip from Florence
Florence Accademia Gallery Tour with Entrance Ticket Included
Skip-the-Line: Best of Florence Guided Walking Tour with Accademia & David
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Best of Florence AudioGuided Walking Tour led by Tour Leader
Top hotels in Santo Spirito
Hotel Horto Convento
The hotel is very nice and well located, you can reach the tourist spots in Florence by walking. The staff is helpful and friendly, and the rooms are comfortable.
Reviewed on 21 Dec 2025
Palazzo Mannaioni Suites
The room was clean the day we got in, the next days they didn’t enter to clean it and the rules where to leave clean the kitchen, if not, they would charge 50 euros
Reviewed on 12 Dec 2025
La Torre Del Cestello
Beautiful place to stay. Just outside of the bustle but walking within distance. Warmly welcomed and staff were lovely.
Reviewed on 25 Dec 2025
UNA Hotels Vittoria Firenze
Super nice reception staffs, everyone is so friendly and welcoming. But don’t like the red room decoration.
Reviewed on 5 Nov 2025
Oltrarno Splendid
Fabulous place to stay
Reviewed on 7 Dec 2025
Casa Santo Nome di Gesù
I always enjoy my stay here. Nicely located, pleasant breakfast, terrific courtyard, nicely priced.
Reviewed on 11 Nov 2025
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Via Maggio while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood.
