Photo by Alice Burghart

Cat & Dog Friendly Hotels in Cape Girardeau

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Our top choices for Cape Girardeau pet-friendly hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! "
United States
Michael
The price is RM364
RM411 total
includes taxes & fees
6 Jan - 7 Jan 2026
Drury Plaza Hotel Cape Girardeau Conference Center

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (104)
"It was a nice stay"
United States
Douglas
The price is RM362
RM412 total
includes taxes & fees
7 Jan - 8 Jan 2026
Tru By Hilton Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is RM283
RM320 total
includes taxes & fees
12 Jan - 13 Jan 2026
Pear Tree Inn Cape Girardeau Near the Medical Center

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Awesome stay!"
United States
Breckin
The price is RM364
RM411 total
includes taxes & fees
12 Jan - 13 Jan 2026
Drury Inn & Suites Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
"Excellent stay"
United States
Christina
The price is RM428
RM483 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hampton Inn Cape Girardeau I 55 East

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (886)
"Room was clean and spacious."
United States
George
The price is RM284
RM343 total
includes taxes & fees
25 Jan - 26 Jan 2026
Candlewood Suites Cape Girardeau by IHG

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is RM223
RM260 total
includes taxes & fees
6 Jan - 7 Jan 2026
Town House Inn Cape Giradreau

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is RM283
RM320 total
includes taxes & fees
12 Jan - 13 Jan 2026
Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is RM336
RM355 total
includes taxes & fees
12 Jan - 13 Jan 2026
Drury Inn & Suites Jackson MO

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (84)
"Cute room, great food, fun soda fountain and friendly owners! Will return! "
United States
Leslie
EC Reed's Mercantile and Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cape Girardeau Hotel Reviews

Frequently asked questions

What's the best dog-friendly hotel in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Other good options to stay with your pet include Tru By Hilton Cape Girardeau and Drury Inn & Suites Cape Girardeau.
How many dog-friendly hotels will I find in Cape Girardeau?
Stay with your furry friend at one of Expedia's 8 dog-friendly Cape Girardeau hotels or accommodation options.
What's the best time of year to travel to Cape Girardeau with my pet?
When you travel with your pet, keeping track of the weather can make the trip safe and fun for everyone. The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.
What is there to see and do with your pet in Cape Girardeau?
Known for its riverfront and university life, Cape Girardeau has lots to offer visitors. See the local sights and visit Isle Casino Cape Girardeau and Show Me Center. While you're there, make sure you don't miss Hunter Valley Winery and Trail of Tears State Park.

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