Calle 50
Visit Calle 50
Tours & day trips
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Slingshot Tour Panama
Private & custom tours
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Jungle ATV Waterfall and Zipline Adventure from Panama City
Cruises & boat tours
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From Panama City: Monkey Islands Tour on Gatun Lake
Classes & workshops
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Learn about Panama cocoa and create your own chocolate bar
Air, helicopter & balloon tours
See all 6 activities
Charter Flights Panama City
Popular places to visit
Soho City Center
You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's shops or seek out its local tours.
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Bingo 90
Why not roll the dice with a visit to Bingo 90 during your travels in Panama City? Visit the shops and casinos in this vibrant area.
National Shrine of the Heart of Mary
You can learn about the history of Panama City with a trip to National Shrine of the Heart of Mary. Stroll along the seaside or visit the shops in this vibrant area.
Top Calle 50 Hotel Deals
Hotel Riu Plaza Panama
Sheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Ramada Plaza By Wyndham Panama Punta Pacífica
Megapolis Hotel Panamá
Principe Hotel and Suites
Decapolis Hotel Panama City
Courtyard by Marriott Panama Multiplaza Mall
