Top 10 Lake Nona Medical City Hotels of 2026

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Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.

The entrance to the Hollywood Studios area with a large sign and distinctive architecture.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

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A large Ferris wheel with a blue light, surrounded by a water fountain display and palm trees.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

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A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

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A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

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A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

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Top Lake Nona Medical City Hotel Reviews

Universal's Cabana Bay Beach Resort

8/10 Good

"Great stay, had an upgrade to a suite brilliant will definitely book again"

Kompose Boutique Resort at Theme Parks

8/10 Good

"Overall a great hotel for the money. Staff were excellent. Rooms were very clean and beds were comfortable. Very little furniture in the room and the shower was only partially closed allowing water to spill onto the floor and cold air to enter. Elevators are very far from most of the rooms. Breakfast was better than most hotels I have stayed at. I would definitely stay at this hotel again."

Marriott's Grande Vista

8/10 Good

"Marriott has a great location with close proximity to Sea World. I was a bit surprised by the amount of the required deposit ($500) at check in.. In addition to the $30 per day self-parking charge (valet is NOT available); I was out of $750 at check in. That meant I essentially paid for my stay once online and then at check in I paid about 85% of that price AGAIN in deposits and parking fees. Also I was SHOCKED to find house-keeping was an ADDITIONAL fee on top of all of this. I thought for a five night stay there would be at least ONE housekeeping session included.. NOT AT ALL. Aside from the absolute nickel and dime fees for EVERYTHING and the VERY aggressive sales pressure to buy their timeshares package. The room was great. The location very convenient. Just be prepared for a substantial deposit when you stay here and beware that they are VERY aggressive in trying to get you to their timeshare sales presentation. A plus is also that their pools stay open until 11pm and they have multiple pools on site."

Drury Plaza Hotel Orlando - Disney Springs Area

10/10 Excellent

"One of the best hotels in Orlando. It has everything a Disney resort should have but doesn’t.The front desk was incredibly helpful and greeted you every time you walked through the door. They were very hospitable and knew their property well. The dining and bar staff were amazing and friendly. The kickback and breakfast was a very much needed accommodation, especially if you’re on a budget. The breakfast was pretty good with a great selection and a waffle iron that featured Mickey’s imprint. Pretty cute. Something like that would have costed $7-10 at Disney. The shuttle bus service was a plus but can get packed fast, so have your key card ready for verification. In all, this hotel has everything needed."

Frequently asked questions

What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.

What's the best accommodation in Lake Nona Medical City?

Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.

How many hotels will I find in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.

What is there to do around this Orlando neighbourhood?

Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.

Hotels in Lake Nona Medical City, Orlando

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Our top choices for Lake Nona Medical City hotels

1. Courtyard Orlando Lake Nona

2. Residence Inn Orlando Lake Nona

3. Aloft by Marriott Orlando Lake Nona

4. Hyatt Regency Orlando International Airport

5. Hyatt House Orlando Airport

6. Hampton Inn & Suites Orlando Airport @ Gateway Village

7. Hyatt Place Orlando Airport

8. avid hotel Orlando International Airport by IHG

9. Holiday Inn Express Orlando International Airport by IHG

10. Wingate by Wyndham - Orlando International Airport

11. Cambria Hotel Orlando Airport

12. EVEN Hotel Orlando International Airport by IHG

13. Ramada by Wyndham Suites Orlando Airport

14. Wyndham Garden Orlando Airport

15. Country Inn & Suites by Radisson, Orlando Airport, FL

16. Hampton Inn Orlando-International Airport

17. La Quinta Inn & Suites by Wyndham Orlando Airport

18. Fairfield Inn By Marriott Orlando Airport

19. Comfort Suites Orlando International Airport

20. Holiday Inn Express Orlando – South Park by IHG

Where to stay in Lake Nona Medical City

Bay Lake

International Drive District

Florida Center

Champions Gate

Reunion

Top Lake Nona Medical City Hotel Reviews

Universal's Cabana Bay Beach Resort

Frequently asked questions

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