Panama City Spa Hotels

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Check availability on Panama City Hotels with Spa

Tonight
4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Panama City Hotels with Spa

Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4.0 star property
Tocumen
8.6 out of 10, Excellent, (1856)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is RM514
RM566 total
includes taxes & fees
3 Jan - 4 Jan 2026
Riande Aeropuerto Hotel & Casino
Couples treatment room(s), sauna, steam room, body treatments
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5.0 star property
Veracruz
8.0 out of 10, Very good, (1000)
"Clean rooms , friendly staff , had great experience "
United States
Saro
The price is RM684
RM753 total
includes taxes & fees
16 Dec - 17 Dec
The Westin Playa Bonita Panama
Couples treatment room(s), sauna, hot tub, steam room
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very good, (1247)
"Its a very beautiful hotel with view and very good breakfast "
United States
Patrick
The price is RM570
RM626 total
includes taxes & fees
3 Jan - 4 Jan 2026
Megapolis Hotel Panamá
Bathroom
JW Marriott Panama

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1002)
"Spotless, friendly and great food. Great pools a restaurants. "
Canada
David
The price is RM1,033
RM1,137 total
includes taxes & fees
4 Jan - 5 Jan 2026
JW Marriott Panama
Couples treatment room(s), steam room, Turkish bath/hammam
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (635)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is RM954
RM1,049 total
includes taxes & fees
12 Dec - 13 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Couples treatment room(s), body treatments, aromatherapy
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (551)
"Great hotel and location "
United Kingdom
Russell
The price is RM1,722
RM1,894 total
includes taxes & fees
5 Jan - 6 Jan 2026
Sofitel Legend Casco Viejo, Panama City
Meeting facility
W Panama

W Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1001)
"Clean room, great views, great staff!"
United States
Ashley
The price is RM830
RM913 total
includes taxes & fees
4 Jan - 5 Jan 2026
W Panama
Body treatments, body wraps, body scrubs, facials, 4 treatment rooms
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (257)
"Great location!"
United States
Erik
The price is RM1,277
RM1,404 total
includes taxes & fees
9 Dec - 10 Dec
Hotel La Compañía Casco Antiguo
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2127)
"Great location, friendly staff, excellent views and the best breakfast around."
Canada
Gregory
The price is RM512
RM563 total
includes taxes & fees
11 Dec - 12 Dec
Plaza Paitilla Inn Hotel
Sports facility
Hilton Panama

Hilton Panama

5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1000)
"Great place to stay."
United States
Salvador
The price is RM766
RM843 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Panama City Hotel Reviews

Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Excellent stay. Wonderful staff, good location and excellent breakfast"
Michael 14-night trip
Posted 1 day ago
Decapolis Hotel Panama City

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Frequently asked questions

Looking to holiday at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Make sure you enjoy the cafes during your stay. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping centre and a rooftop terrace. Enjoy a facial, body scrub or detox wrap at the on-site spa. Other popular spa hotels in Panama City include W Panama and Las Americas Golden Tower Panama.
How many spa hotels are there in Panama City?
Expedia has 24 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Crown Casino.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas and offer services including facials and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.