Cheap flights from Missouri starting at

Popular airlines from Missouri

  • American Airlines

    American Airlines

  • Delta

    Delta

  • United

    United

  • Southwest Airlines

    Southwest Airlines

  • Frontier Airlines

    Frontier Airlines

  • Air Canada

    Air Canada

  • Alaska Airlines

    Alaska Airlines

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Missouri

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,652 Return, found 6 days ago
RM1,652
Return
found 6 days ago
Select Delta flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,652 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,709 Return, found 6 days ago
RM1,709
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,709 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,725 Return, found 6 days ago
RM1,725
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,725 found 6 days ago
American Airlines
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,728 Return, found 6 days ago
RM1,728
Return
found 6 days ago
Select American Airlines flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,728 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,730 Return, found 6 days ago
RM1,730
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,730 found 6 days ago
American Airlines
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,732 Return, found 6 days ago
RM1,732
Return
found 6 days ago
Select American Airlines flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,732 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,748 Return, found 6 days ago
RM1,748
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,748 found 6 days ago
American Airlines
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,751 Return, found 6 days ago
RM1,751
Return
found 6 days ago
Select American Airlines flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,751 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,753 Return, found 6 days ago
RM1,753
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,753 found 6 days ago
Delta
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,773 Return, found 6 days ago
RM1,773
Return
found 6 days ago
Select Delta flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,773 found 6 days ago
Delta
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,776 Return, found 6 days ago
RM1,776
Return
found 6 days ago
Select Delta flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,776 found 6 days ago
American Airlines
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,794 Return, found 6 days ago
RM1,794
Return
found 6 days ago
Select American Airlines flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,794 found 6 days ago
American Airlines
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,817 Return, found 6 days ago
RM1,817
Return
found 6 days ago
Select American Airlines flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,817 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,834 Return, found 6 days ago
RM1,834
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,834 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,835 Return, found 6 days ago
RM1,835
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,835 found 6 days ago
Delta
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,841 Return, found 6 days ago
RM1,841
Return
found 6 days ago
Select Delta flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,841 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,850 Return, found 6 days ago
RM1,850
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,850 found 6 days ago
American Airlines
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,853 Return, found 6 days ago
RM1,853
Return
found 6 days ago
Select American Airlines flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,853 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,855 Return, found 6 days ago
RM1,855
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,855 found 6 days ago
United
Fri, 23 Jan - Fri, 30 Jan
STL
St. Louis
SAN
San Diego
RM1,856 Return, found 6 days ago
RM1,856
Return
found 6 days ago
Select United flight, departing Fri, 23 Jan from St. Louis to San Diego, returning Fri, 30 Jan, priced at RM1,856 found 6 days ago

Explore a world of travel with Expedia

*Available to Expedia members.