What's it like in Uptown Central?

Guests are sure to enjoy their time checking out all that San Antonio's Uptown Central neighbourhood has to offer. Are you looking for Uptown Central travel tips? Make sure that you visit Marion Koogler McNay Art Museum and Alamo Quarry Market while you're in the neighbourhood.

What's the best accommodation in Uptown Central?

Based on our traveller data, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is one of the top choices for your stay in Uptown Central. This hotel is a short 14-minute walk from North Star Mall, and it offers free breakfast and an outdoor pool. Other good options for your stay in the area include Wyndham Garden San Antonio Airport and La Quinta Inn & Suites by Wyndham San Antonio Airport .

How many hotels will I be able to find in the Uptown Central area?

Expedia has 392 hotels and other accommodation options in Uptown Central to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Uptown Central, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Uptown Central.

What can I see and do in this San Antonio neighbourhood?

Uptown Central's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to Alamo Quarry Market or San Antonio Zoo and Aquarium while you're in the neighbourhood. A few places to visit in the area around Uptown Central include Harry B Orem Stadium, Quarry Golf Club and Regal Alamo Quarry. McDermott Center and Gayle and Tom Benson Stadium are also worth a visit when you're out sightseeing in San Antonio.

Top 10 Uptown Central Hotels of 2026

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Our top choices for Uptown Central hotels

A Holiday Inn Express reception desk with a modern design, featuring a large illuminated sign, a reception area, and a potted plant.

1. Holiday Inn Express San Antonio-Airport by IHG

Uptown Central

Lori

RM508 total

includes taxes & fees

22 Nov - 23 Nov

A modern lobby with a sofa, patterned chairs, a central ottoman, and a chandelier.

2. Drury Plaza Hotel San Antonio Airport

Uptown Central

Darlene

RM552 total

includes taxes & fees

25 Nov - 26 Nov

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

3. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown Central

Elsa

RM383 total

includes taxes & fees

15 Nov - 16 Nov

A multi-level hotel atrium with a central open space, seating areas, and a large artwork on the left.

4. Embassy Suites by Hilton San Antonio Airport

Uptown Central

Trenton

RM612 total

includes taxes & fees

29 Nov - 30 Nov

A modern living room with a sofa, coffee table, and a large abstract painting.

5. Marriott San Antonio Airport

Uptown Central

Amy

RM600 total

includes taxes & fees

28 Nov - 29 Nov

A lobby with a central seating area, a reception desk, and a kitchenette in the background.

6. Homewood Suites by Hilton San Antonio Airport

Uptown Central

Jessica

RM494 total

includes taxes & fees

28 Nov - 29 Nov

An outdoor patio area with stone pillars, a round table, and chairs.

7. Wyndham Garden San Antonio Airport

Uptown Central

Johnny

RM407 total

includes taxes & fees

3 Nov - 4 Nov

A spacious living area with a dark blue sofa, four grey armchairs, and three metallic coffee tables.

8. La Quinta Inn & Suites by Wyndham San Antonio Airport

Uptown Central

Vanesa

RM384 total

includes taxes & fees

25 Nov - 26 Nov

A hotel entrance with a wet driveway, large windows, and a tree in the foreground.

9. Courtyard by Marriott San Antonio Airport

Uptown Central

Lonnie

RM431 total

includes taxes & fees

13 Nov - 14 Nov

An outdoor patio with metal chairs, a barbecue grill, and string lights.

10. Home2 Suites by Hilton San Antonio Airport, TX

Uptown Central

Allan

RM511 total

includes taxes & fees

15 Nov - 16 Nov

A hotel pool area with two pools, a spa lift, and a wheelchair-accessible sign.

11. Hilton Garden Inn San Antonio Airport South

Uptown Central

Willard

RM445 total

includes taxes & fees

15 Nov - 16 Nov

A multi-level hotel atrium with a central courtyard, outdoor seating, and a swimming pool.

12. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Uptown Central

Lauro

RM611 total

includes taxes & fees

29 Nov - 30 Nov

A spacious hotel lobby with a long marble reception desk, multiple seating areas, and a large television screen.

13. Hampton Inn & Suites San Antonio-Airport

Uptown Central

Omar

RM402 total

includes taxes & fees

29 Nov - 30 Nov

A hotel lobby with a reception desk, seating area with sofas and chairs, and a patterned carpet.

14. TownePlace Suites by Marriott San Antonio Airport

Uptown Central

Alejandro

RM540 total

includes taxes & fees

22 Nov - 23 Nov

A modern interior with a curved ceiling, a sectional sofa, a round coffee table, and a dining area with chairs and a table.

15. SpringHill Suites by Marriott San Antonio Airport

Uptown Central

jennifer

RM434 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio area with a fire pit, seating, and string lights.

16. Residence Inn By Marriott San Antonio Airport/Alamo Heights

Uptown Central

veronica

RM605 total

includes taxes & fees

13 Nov - 14 Nov

A hotel lobby with a reception desk, seating area, and a 'Connect & Print' station.

17. Fairfield Inn & Suites San Antonio Airport/North Star Mall

Uptown Central

david m,

RM368 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with two beds, a desk, a chair, and a large window with curtains.

18. Spark by Hilton San Antonio Airport

Uptown Central

Brian

RM345 total

includes taxes & fees

9 Nov - 10 Nov

A spacious lobby with a beige sofa, a chandelier, a staircase, and a large window overlooking a parking area.

19. Days Inn by Wyndham San Antonio Airport

Uptown Central

LUCERO

RM284 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lounge area with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.

20. Staybridge Suites San Antonio by IHG

Uptown Central

riccara

RM362 total

includes taxes & fees

1 Dec - 2 Dec

View all properties

Compare popular hotels in Uptown Central

Property	Property class	Guest rating
Drury Plaza Hotel San Antonio Airport	3.0 star property	9.4 Exceptional 2,314 reviews	View
Holiday Inn Express San Antonio-Airport by IHG	2.5 star property	9.4 Exceptional 1,000 reviews	View
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham	2.5 star property	9.0 Wonderful 2,352 reviews	View
Estancia del Norte San Antonio, Tapestry Collection by Hilton	3.5 star property	9.0 Wonderful 1,001 reviews	View
Spark by Hilton San Antonio Airport	2.0 star property	8.8 Excellent 1,865 reviews	View

Where to stay in Uptown Central

Find the best Uptown Central areas for the activities you enjoy most.

A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

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A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

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A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

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A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

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A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

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Top Uptown Central Hotel Reviews

Drury Plaza Hotel San Antonio Riverwalk

8/10 Good

"Like I mentioned before amenities the fact they were offering breakfast and dinner totally amazing the only think was the cleanliness of the room, I found at lot of dust in the room, for example by fixtures, tables legs and dresser where TV was located and around the corner more than nothing by the beds, dust built-up can bring a lot of spiderweb."

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

8/10 Good

"Staff upon check in was super nice, I believe his name was Alexander. Great recommendations on what to do and where to go for my parent’s wedding anniversary. We were supposed to have a surprise for my parent’s anniversary set up in the room but the staff never went in and set it up. We were disappointed with that. The rooms were great though, kitchen, restrooms all were perfect. My parents really enjoyed it as well. The rain unfortunately didn’t let us partake in a lot of the outdoor activities. I hope we get to visit again."

Red Roof Inn San Antonio - Airport

10/10 Excellent

"Every time I stay at this particular location, I’m always treated with a warm welcome. The rooms are clean. It’s very quiet and very convenient. The location, and I absolutely love how they allow one free pet. It just really helps, especially when you travel a lot. Great staff! And really, really affordable"

Hotels in Uptown Central, San Antonio

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Our top choices for Uptown Central hotels

1. Holiday Inn Express San Antonio-Airport by IHG

2. Drury Plaza Hotel San Antonio Airport

3. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

4. Embassy Suites by Hilton San Antonio Airport

5. Marriott San Antonio Airport

6. Homewood Suites by Hilton San Antonio Airport

7. Wyndham Garden San Antonio Airport

8. La Quinta Inn & Suites by Wyndham San Antonio Airport

9. Courtyard by Marriott San Antonio Airport

10. Home2 Suites by Hilton San Antonio Airport, TX

11. Hilton Garden Inn San Antonio Airport South

12. Estancia del Norte San Antonio, Tapestry Collection by Hilton

13. Hampton Inn & Suites San Antonio-Airport

14. TownePlace Suites by Marriott San Antonio Airport

15. SpringHill Suites by Marriott San Antonio Airport

16. Residence Inn By Marriott San Antonio Airport/Alamo Heights

17. Fairfield Inn & Suites San Antonio Airport/North Star Mall

18. Spark by Hilton San Antonio Airport

19. Days Inn by Wyndham San Antonio Airport

20. Staybridge Suites San Antonio by IHG

Compare popular hotels in Uptown Central

Where to stay in Uptown Central

Downtown San Antonio

Far West Side

Medical Center District

Northwest Side

Stone Oak

Top Uptown Central Hotel Reviews

Drury Plaza Hotel San Antonio Riverwalk

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