Photo by Sarah C.

Hotels in Uptown, San Antonio

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
3 Dec - 4 Dec
Tomorrow
4 Dec - 5 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in Uptown, San Antonio

Lobby
Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport

3.0 star property
Uptown
9.4 out of 10, Exceptional, (1001)
"The staff was amazing ! The kickbacks and free drinks every night we stayed were delish ! I will definitely stay there again :) "
United States
bertha
The price is RM389
RM460 total
includes taxes & fees
7 Dec - 8 Dec
Wyndham Garden San Antonio Airport
Reception
Best Western Garden Inn

Best Western Garden Inn

2.5 star property
Uptown
8.2 out of 10, Very good, (1001)
"Clean room, friendly and helpful staff."
United States
Robyn
The price is RM245
RM287 total
includes taxes & fees
17 Dec - 18 Dec
Best Western Garden Inn
Lobby
Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport

3.0 star property
Uptown
9.4 out of 10, Exceptional, (1933)
"Great hotel in the center of everything. Loved all the food benefits and felt safe, nice parking too!"
United States
Ashley
The price is RM371
RM439 total
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Plaza Hotel San Antonio Airport
Terrace/patio
Hampton Inn & Suites San Antonio-Airport

Hampton Inn & Suites San Antonio-Airport

2.5 star property
Uptown
8.4 out of 10, Very good, (1730)
"I had a great stay "
United States
Carol
The price is RM327
RM388 total
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn & Suites San Antonio-Airport
Exterior
La Quinta Inn & Suites by Wyndham San Antonio Airport

La Quinta Inn & Suites by Wyndham San Antonio Airport

3.0 star property
Uptown
7.8 out of 10, Good, (2839)
"Courteous staff , clean bed & bathrooms"
United States
Ralph
The price is RM310
RM367 total
includes taxes & fees
10 Dec - 11 Dec
La Quinta Inn & Suites by Wyndham San Antonio Airport
Lobby sitting area
Crowne Plaza San Antonio Airport by IHG

Crowne Plaza San Antonio Airport by IHG

3.5 star property
Uptown
8.4 out of 10, Very good, (1483)
"Nice courteous staff, clean room"
United States
Tina
The price is RM294
RM347 total
includes taxes & fees
7 Dec - 8 Dec
Crowne Plaza San Antonio Airport by IHG
Free WiFi, bed sheets
Red Roof Inn San Antonio - Airport

Red Roof Inn San Antonio - Airport

2.0 star property
Uptown
8.2 out of 10, Very good, (1111)
"Staff was so friendly "
United States
Shqiprim
The price is RM189
RM224 total
includes taxes & fees
9 Dec - 10 Dec
Red Roof Inn San Antonio - Airport
Lobby sitting area
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2.5 star property
Uptown
9.4 out of 10, Exceptional, (1510)
"Rooms were clean and staff was great."
United States
Victoria
The price is RM347
RM410 total
includes taxes & fees
7 Dec - 8 Dec
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Free daily on-the-go breakfast
Homewood Suites by Hilton San Antonio Airport

Homewood Suites by Hilton San Antonio Airport

3.0 star property
Uptown
8.6 out of 10, Excellent, (1001)
"Great stay"
United States
Meredith
The price is RM426
RM506 total
includes taxes & fees
14 Dec - 15 Dec
Homewood Suites by Hilton San Antonio Airport
Premium bedding, desk, laptop workspace, blackout curtains
Spark by Hilton San Antonio Airport

Spark by Hilton San Antonio Airport

2.0 star property
Uptown
8.6 out of 10, Excellent, (1007)
"Great time staying at this location."
United States
Amy
The price is RM264
RM313 total
includes taxes & fees
29 Dec - 30 Dec
Spark by Hilton San Antonio Airport
Free daily continental breakfast
Comfort Suites San Antonio North - Stone Oak

Comfort Suites San Antonio North - Stone Oak

2.5 star property
Uptown
8.6 out of 10, Excellent, (1000)
"Excellent stay, great place highly recommended "
United States
Cesar
The price is RM312
RM364 total
includes taxes & fees
10 Dec - 11 Dec
Comfort Suites San Antonio North - Stone Oak
Breakfast served
Embassy Suites by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport

3.5 star property
Uptown
9.0 out of 10, Wonderful, (1070)
"Great stay!"
United States
darryl
The price is RM492
RM581 total
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites by Hilton San Antonio Airport
Free daily on-the-go breakfast
SureStay Plus Hotel by Best Western San Antonio North

SureStay Plus Hotel by Best Western San Antonio North

2.5 star property
Uptown
7.0 out of 10, Good, (1000)
"The staff members were very helpful and friendly, my room was clean and check-in was a smooth process "
United States
Reginald
The price is RM198
RM232 total
includes taxes & fees
4 Dec - 5 Dec
SureStay Plus Hotel by Best Western San Antonio North
Lobby sitting area
Days Inn by Wyndham San Antonio Airport

Days Inn by Wyndham San Antonio Airport

2.0 star property
Uptown
8.2 out of 10, Very good, (1002)
"Great place to lie your head right close to the airport "
Canada
Kevin
The price is RM216
RM252 total
includes taxes & fees
4 Dec - 5 Dec
Days Inn by Wyndham San Antonio Airport
Free buffet breakfast
Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG

2.5 star property
Uptown
9.4 out of 10, Exceptional, (1019)
"Everything during our stay was great. Staff was very friendly, the room was clean, breakfast was good. "
United States
Thais
The price is RM360
RM425 total
includes taxes & fees
20 Dec - 21 Dec
Holiday Inn Express San Antonio-Airport by IHG
Exterior
Home2 Suites by Hilton San Antonio Airport, TX

Home2 Suites by Hilton San Antonio Airport, TX

3.0 star property
Uptown
8.6 out of 10, Excellent, (1009)
"Very good stay "
United States
Roberto
The price is RM360
RM425 total
includes taxes & fees
14 Dec - 15 Dec
Home2 Suites by Hilton San Antonio Airport, TX
Reception
Super 8 by Wyndham San Antonio Airport North

Super 8 by Wyndham San Antonio Airport North

2.5 star property
Uptown
7.4 out of 10, Good, (1000)
"Staff is excellent. "
United States
Sabrena
The price is RM242
RM282 total
includes taxes & fees
14 Dec - 15 Dec
Super 8 by Wyndham San Antonio Airport North
Terrace/patio
Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South

3.0 star property
Uptown
8.4 out of 10, Very good, (1001)
"Friendly Staff and Clean Room"
United States
Patrick
The price is RM314
RM379 total
includes taxes & fees
28 Dec - 29 Dec
Hilton Garden Inn San Antonio Airport South
Exterior
Baymont by Wyndham San Antonio Airport

Baymont by Wyndham San Antonio Airport

2.0 star property
Uptown
6.2 out of 10, (888)
"Stay was quiet and peaceful. Nice and courteous staff"
United States
Jennifer
The price is RM175
RM205 total
includes taxes & fees
1 Jan - 2 Jan 2026
Baymont by Wyndham San Antonio Airport
Exterior
Courtyard by Marriott San Antonio Airport

Courtyard by Marriott San Antonio Airport

3.0 star property
Uptown
8.4 out of 10, Very good, (1000)
"Very friendly and courteous staff, great breakfast."
United States
Viju
The price is RM382
RM452 total
includes taxes & fees
13 Dec - 14 Dec
Courtyard by Marriott San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.
Downtown - Riverwalk showing heritage architecture, a bridge and boating

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and The San Antonio Art Institute.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Top Uptown Hotel Reviews

Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

10/10 Excellent
"Great atmosphere and space. highly recommend."
Cynthia 7-night trip
Posted 17 hours ago
Sonesta ES Suites San Antonio Downtown Alamo Plaza

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Uptown?
Guests are sure to enjoy their time checking out all that San Antonio's Uptown neighbourhood has to offer. Are you looking for Uptown travel tips? Make sure that you visit Marion Koogler McNay Art Museum and Alamo Quarry Market while you're in the neighbourhood.
What's the best accommodation in Uptown?
Based on Expedia customer reviews, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is the highest ranked property in Uptown. This hotel offers free breakfast and an outdoor pool. Other top choices in the neighbourhood include Wyndham Garden San Antonio Airport and Drury Plaza Hotel San Antonio Airport.
How many hotels will I be able to find in the Uptown area?
Expedia has 373 hotels and other accommodation options in Uptown to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Uptown, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Uptown.
What can I see and do in this San Antonio neighbourhood?
Uptown's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to Alamo Quarry Market or San Antonio Zoo and Aquarium while you're in the neighbourhood. A few places to visit in the area around Uptown include Harry B Orem Stadium, Quarry Golf Club and Regal Alamo Quarry. McDermott Center and UIW Tennis Center are also worth a visit when you're out sightseeing in San Antonio.