A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

St. Charles Spa Hotels

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Check availability on St. Charles Hotels with Spa

Tonight
30 Sept - 1 Oct
Tomorrow
1 Oct - 2 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for St. Charles hotels with a spa

A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
RM609
RM780 total
includes taxes & fees
14 Oct - 15 Oct
Ameristar Casino Resort and Spa
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
RM586
RM706 total
includes taxes & fees
1 Nov - 2 Nov
21C Museum Hotel St Louis
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.
A two-story building with a dark entrance, large windows, and a brick facade.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

3. Truitt Hotel

Truitt Hotel
Lafayette Square
RM767
RM928 total
includes taxes & fees
12 Oct - 13 Oct
Truitt Hotel
A couple relaxing by a window overlooking a bridge and water.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

4. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
RM1,530
RM1,789 total
includes taxes & fees
11 Oct - 12 Oct
Four Seasons Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A couple standing on a balcony with a cityscape view.
A bar area with leather seating, a bar counter, and shelves of bottles.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

5. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
RM2,362
RM2,758 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in St. Charles

Pool
Hot tub
Breakfast included
4 stars
5 stars

Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Our time spent at the Drury Hotel was a wonderful experience! The breakfast and evening appetizers were amazing. The 3 free drinks were a big bonus. The staff was extremely friendly and helpful. We will book with them again in the future."
Randi 3-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis Union Station
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Very happy with our stay. Everyone was so friendly and helpful. Room was great and the food was good"
Patrick D. 1-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Our room was very clean. We loved how calm our stay was. We appreciated how welcoming was Ms. Doris at the front desk. We felt valued as the guests, all our questions were answered. We definitely will be back again!"
Jon 1-night trip
Posted 8 hours ago
Pear Tree Inn St. Louis Near Union Station
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

8/10 Good
"nice size free parking spots in the garage. Breakfast was slim. one morning just had sausage and eggs and waffles. next morning had biscuits and gravy and waffles. hotel was clean staffing was friendly. location was good. The cookies were delicious."
Scott 2-night trip
Posted 2 days ago
Country Inn & Suites by Radisson, St. Charles Historic District
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent
"Cory greeted me well before our check in time, allowed me to drop bags. I asked for some time to do work and needed WiFi, he said he couldn’t unless I was a Hilton honors member and helped me create. Also gave me a breakfast pass even thought we weren’t officially checked in. Very accommodating to our needs. Great stay! Would very much go back again!"
James 4-night trip
Posted 2 days ago
Embassy Suites by Hilton St. Louis St. Charles
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

10/10 Excellent
"Friendly and helpful staff. Very good breakfast and coffee. Clean rooms."
Socorro 1-night trip
Posted 5 days ago
Hampton Inn St. Charles St. Peters

Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your holiday. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness centre and an outdoor pool. Treat yourself to a facial, body scrub or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia's 178 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Katy Trail and Lewis & Clark Boathouse and Nature Center. If you have some spare time during your trip, you might want to check out St Charles Convention Center and Ameristar Casino St. Charles.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.

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