Photo by Southernmost Illinois Tourism Bureau

Southwest Illinois hotels from RM216

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1390)
"Great breakfasts and comfortable, quiet rooms "
The price is RM399
RM451 total
includes taxes & fees
10 Aug - 11 Aug
Drury Plaza Hotel Mt. Vernon

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
8.8 out of 10, Excellent, (832)
"Very good place to stay"
The price is RM363
RM403 total
includes taxes & fees
27 Jul - 28 Jul
SureStay Hotel by Best Western Whittington Rend Lake

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (454)
"Excellent stay!"
The price is RM441
RM490 total
includes taxes & fees
3 Aug - 4 Aug
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Quality Inn & Suites Vandalia near I-70 and Hwy 51

2.5 star property
8.4 out of 10, Very good, (1002)
"Was very clean and quiet. Great place to stay after a long drive !"
The price is RM286
RM312 total
includes taxes & fees
14 Aug - 15 Aug
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Holiday Inn Express & Suites Salem by IHG

2.5 star property
9.4 out of 10, Exceptional, (710)
"Great hospitality, clean rooms and a nice breakfast!"
The price is RM501
RM561 total
includes taxes & fees
17 Aug - 18 Aug
Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

2.5 star property
9.0 out of 10, Wonderful, (894)
"Great friendly staff, clean rooms and breakfast was great! Especially the pancakes "
The price is RM467
RM560 total
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express & Suites Vandalia by IHG

2.5 star property
8.8 out of 10, Excellent, (713)
"Very nice facility and super easy by Highway. Definitely would stay again."
The price is RM492
RM536 total
includes taxes & fees
27 Jul - 28 Jul
Holiday Inn Express & Suites Vandalia by IHG

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1006)
"Clean and convenient to all local activities "
The price is RM424
RM509 total
includes taxes & fees
16 Aug - 17 Aug
Drury Inn & Suites Marion

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (95)
"Perfect stay! "
The price is RM479
RM531 total
includes taxes & fees
20 Jul - 21 Jul
The Principal Hotel

Best Western Marion Hotel

2.5 star property
8.2 out of 10, Very good, (1000)
"Very clean nice rooms friendly staff"
The price is RM332
RM399 total
includes taxes & fees
27 Jul - 28 Jul
Best Western Marion Hotel

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

2.5 star property
8.8 out of 10, Excellent, (657)
"Great place to stay"
The price is RM465
RM524 total
includes taxes & fees
2 Aug - 3 Aug
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Powhatan Motel

2.5 star property
8.6 out of 10, Excellent, (174)
"Wonderful place to stay."
The price is RM411
RM435 total
includes taxes & fees
20 Jul - 21 Jul
Powhatan Motel

Baymont by Wyndham Chester IL

2.5 star property
8.6 out of 10, Excellent, (321)
"Great quick clean stay"
The price is RM391
RM434 total
includes taxes & fees
14 Aug - 15 Aug
Baymont by Wyndham Chester IL

Baymont by Wyndham Marion

2.5 star property
8.4 out of 10, Very good, (1035)
"Great hotel , stayed for a month for work and was please with the staff friendliness and attentiveness "
The price is RM383
RM460 total
includes taxes & fees
27 Jul - 28 Jul
Baymont by Wyndham Marion

Super 8 by Wyndham Greenville

2.0 star property
8.0 out of 10, Very good, (715)
"The hotel was very pet friendly"
The price is RM290
RM322 total
includes taxes & fees
28 Jul - 29 Jul
Super 8 by Wyndham Greenville

Ramada by Wyndham Vandalia

2.0 star property
7.8 out of 10, Good, (778)
"Good property"
The price is RM314
RM342 total
includes taxes & fees
3 Aug - 4 Aug
Ramada by Wyndham Vandalia

Comfort Suites Mount Vernon

2.5 star property
8.8 out of 10, Excellent, (1003)
"We stayed here as a stop for the night and were quite pleased with this motel."
The price is RM506
RM570 total
includes taxes & fees
20 Jul - 21 Jul
Comfort Suites Mount Vernon

Best Western U. S. Inn

2.5 star property
8.6 out of 10, Excellent, (371)
"After traveling 8 hours and trying to find a hotel in the St. Louis area with no luck. We were very pleased to find this hotel. Very clean & great breakfast too! "
The price is RM509
RM555 total
includes taxes & fees
20 Jul - 21 Jul
Best Western U. S. Inn

Super 8 by Wyndham Okawville

2.0 star property
7.2 out of 10, Good, (284)
"Lots of parking for truck and trailer. "
The price is RM281
RM312 total
includes taxes & fees
16 Aug - 17 Aug
Super 8 by Wyndham Okawville

Super 8 by Wyndham Mt. Vernon IL

2.5 star property
7.8 out of 10, Good, (1002)
"We had a good stay, room was clean and comfortable. Would stay again."
The price is RM264
RM302 total
includes taxes & fees
10 Aug - 11 Aug
Super 8 by Wyndham Mt. Vernon IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Southwest Illinois

Live music, sports teams and sights from Rainbow Ranch Petting Zoo to Pyramid State Recreation Area—discover it all in Southwest Illinois.

Southern Illinois featuring a lake or waterhole and forests
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southwest Illinois Hotel Reviews