10 Best Business Hotels in Southern Minnesota for 2026

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Our top choices for Southern Minnesota business-friendly hotels

Desk, blackout curtains, soundproofing, iron/ironing board

1. AmericInn by Wyndham Sleepy Eye

Sleepy Eye

Angie

RM414

RM465 total

includes taxes & fees

6 Sept - 7 Sept

Desk, laptop workspace, iron/ironing board, free WiFi

2. Best Western Plus New Ulm

New Ulm

Walter

RM487

RM540 total

includes taxes & fees

6 Sept - 7 Sept

Desk, blackout curtains, iron/ironing board, free WiFi

3. AmericInn by Wyndham Mankato Event Center

Mankato

Andrew

RM323

RM358 total

includes taxes & fees

23 Aug - 24 Aug

Desk, iron/ironing board, cots/infant beds, rollaway beds

4. AmericInn by Wyndham Jackson

Jackson

Rose

RM376

RM417 total

includes taxes & fees

9 Aug - 10 Aug

Free minibar, desk, iron/ironing board, free cots/infant beds

5. Super 8 by Wyndham St. James

Saint James

Denise

RM389

RM425 total

includes taxes & fees

9 Aug - 10 Aug

Indoor pool, pool cabanas (surcharge), pool loungers

Body treatments, hot stone massages, deep-tissue massages

6. Treasure Island Resort & Casino

Welch

Julie

RM312

RM393 total

includes taxes & fees

7 Sept - 8 Sept

7. AmericInn by Wyndham Windom

Windom

Lon

RM501

RM551 total

includes taxes & fees

30 Aug - 31 Aug

In-room safe, desk, blackout curtains, soundproofing

8. Super 8 by Wyndham Jackson MN

Jackson

Gerardo

RM327

RM363 total

includes taxes & fees

3 Sept - 4 Sept

View all properties

Top Southern Minnesota Hotel Reviews

Brentwood Inn & Suites

8/10 Good

"Clean rooms and property. Breakfast was very basic."

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"Enjoyable stay. Nice restaurant. Close to civic center. Shuttle is a real nice extra. Respectful staff. Dated physically, lots of traffic with Mayo near bye. They seem to own near by buildings as well."

Hampton Inn Rochester-South

10/10 Excellent

"We needed a single nights stay and this hotel has worked very well several times. Nice breakfast and soup for an evening meal."

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"Check i and out is always fast, Staff is very helpful and the free breakfast is nice, are room was clean and comfortable."

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good

"We were only there for one night and the entire experience was good. The breakfast was mediocre and pretty typical for free continental breakfast. The hot tub was not in working order, but that happens on occasion. The staff was excellent and very friendly at check-in and allowed us to even have a late checkout, which was helpful. I would stay at this hotel again."

Kahler Grand Hotel

8/10 Good

"Very close to Mayo clinic and the Peace Plaza. Rooms are very small."

St James Hotel, a Historic Hotel of America

10/10 Excellent

"Fastest check in I've ever experienced, lovely atmosphere."

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"Great staff and service. Happy hour at the bar was fabulous."

Frequently asked questions

How much do business-friendly hotels in Southern Minnesota cost?

Prepare to pay between RM358 and RM551 per night for business-friendly hotels in Southern Minnesota. Terrific deals on stays that cater to corporate travellers are just a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Southern Minnesota?

That depends on your destination in Southern Minnesota. Many business travellers to Rochester like staying at Hilton Rochester Mayo Clinic Area. This 3.5-stars property comes with pool sun loungers and a spa. Home2 Suites by Hilton Rochester Mayo Clinic Area is another excellent option if you're attending a conference or working remotely in Rochester. Private winery tours and pool sun loungers are among the useful amenities at this 3-stars getaway. You can choose from multiple business-friendly hotels in Southern Minnesota that have a total average guest review rating of 8.8.

How many business-friendly hotels are there in Southern Minnesota?

When work takes you on the road in Southern Minnesota, you'll have 126 business-friendly hotels to select from.

What are the best cheap business-friendly hotels in Southern Minnesota?

Keep your accountant happy with our business-friendly hotels in Southern Minnesota that start at only RM358 per night. An economical option in Rochester is Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys. Corporate travellers recommend it for its many amenities, such as a tennis court and a swimming pool. If you're headed to Mankato, check out Fairfield Inn & Suites Mankato. A swimming pool and pillow top mattresses are among the conveniences that make it easy to both work and feel at home here. There are tons of fabulous and free attractions around Southern Minnesota. If you have a meeting or conference in Rochester, try to find time in your schedule for Cascade Lake Beach. You can also see the sights without spending your dollars in Mankato. Minneopa State Park is one of the best free things to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the top business-friendly motels in Southern Minnesota?

Expedia's business-friendly motels in Southern Minnesota come with amenities that let you mix work and play. One of our best options is Med City Inn & Suites - Mayo Clinic Area in Rochester. Located around 2 kilometers west of the downtown area, pool sun loungers and a swimming pool are the start of its many conveniences. Another stay that caters to corporate travellers is Baymont by Wyndham Rochester Mayo Clinic Area. It's approximately 2 kilometers south of central Rochester and includes a swimming pool, WiFi and more.Rochester offers a wide range of terrific attractions. Visit Mayowood Mansion and Rochester Civic Theatre if you find yourself with some free time.

Are there any family-friendly hotels in Southern Minnesota that are also business friendly?

Certainly. You'll find some wonderful family-friendly hotels that are also business friendly in Southern Minnesota. If you're travelling to Rochester, check out Comfort Inn & Suites West - Medical Centre. It comes with amenities such as pillow top mattresses and housekeeping services and has a 3-stars rating. Another property worth considering is DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area. This 4-stars stay in Rochester is ideal for both leisure and business travellers and offers a playground, a sauna and plenty more. Rochester has tons of family-friendly attractions when you're ready to see the sights. Mayowood Mansion and Minnesota Children's Museum promise fun for the whole crew.

Are there any 5-star business-friendly hotels in Southern Minnesota?

While there aren't any 5-star business-friendly hotels in Southern Minnesota, there are still stylish properties to choose from. Heading to Rochester for work? DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area is a popular option that has everything you need and more when you're away on business. Amenities at this 4-star property include designer toiletries and a sauna. The Towers At Kahler Grand Hotel is another recommendation that caters to corporate guests in Rochester. Also with a 4-star rating and offering designer toiletries and concierge services, it'll feel like your home away from home.

Why book your business-friendly hotel in Southern Minnesota with Expedia?

Here at Expedia, our top task is to help you find an ideal stay at the right price. From fancy, corporate-friendly retreats to affordable hotels loaded with conveniences, you'll have your next work trip booked in just a few clicks.

How can I find cheap business-friendly hotels in Southern Minnesota?

Click on the "business friendly" filter, located under the "traveller experience" heading, to find cheap business-friendly hotels in Southern Minnesota. Then fine-tune your search by your per-night budget. Staying in a less popular neighbourhood is another easy way to save.

What is there to do in Southern Minnesota near my business-friendly hotel?

Whether you're into shopping, sightseeing, relaxation or adventure, Southern Minnesota offers it all, and then some! The fabulous city of Rochester is home to lots of things to do and see, including Rochester Civic Theatre, Minnesota Children's Museum and Cascade Lake Beach. If you're planning a business trip to Mankato, Mount Kato Ski Area, WOW Zone Family Entertainment Centre and Betsy & Tacy's House Tours & Gift Shop have to be on your itinerary.

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Southern Minnesota Business Hotels

Our top choices for Southern Minnesota business-friendly hotels

1. AmericInn by Wyndham Sleepy Eye

2. Best Western Plus New Ulm

3. AmericInn by Wyndham Mankato Event Center

4. AmericInn by Wyndham Jackson

5. Super 8 by Wyndham St. James

6. Treasure Island Resort & Casino

7. AmericInn by Wyndham Windom

8. Super 8 by Wyndham Jackson MN

9. Best Western Plus Saint Peter

10. AmericInn by Wyndham St. Peter

Top Southern Minnesota Hotel Reviews

Brentwood Inn & Suites

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Hampton Inn Rochester-South

Kahler Inn and Suites - Mayo Clinic Area

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Kahler Grand Hotel

St James Hotel, a Historic Hotel of America

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Frequently asked questions

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