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Southern Illinois hotels from RM277
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Our top choices for Southern Illinois hotels

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,687 reviews)
The price is RM512
RM576 total
includes taxes & fees
28 May - 29 May

Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
9.0 out of 10, Wonderful, (1,004 reviews)
The price is RM452
RM510 total
includes taxes & fees
7 Jun - 8 Jun

Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (737 reviews)
The price is RM591
RM656 total
includes taxes & fees
25 May - 26 May

La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,002 reviews)
The price is RM469
RM525 total
includes taxes & fees
8 Jun - 9 Jun

Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
9.0 out of 10, Wonderful, (1,046 reviews)
The price is RM447
RM504 total
includes taxes & fees
31 May - 1 Jun

Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.2 out of 10, Wonderful, (678 reviews)
The price is RM436
RM489 total
includes taxes & fees
31 May - 1 Jun

Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,000 reviews)
The price is RM384
RM426 total
includes taxes & fees
31 May - 1 Jun

Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
9.0 out of 10, Wonderful, (1,001 reviews)
The price is RM451
RM515 total
includes taxes & fees
26 May - 27 May

Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
8.4 out of 10, Very good, (1,000 reviews)
The price is RM359
RM398 total
includes taxes & fees
6 Jun - 7 Jun

Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,001 reviews)
The price is RM495
RM594 total
includes taxes & fees
24 May - 25 May

Best Western Delta Inn
Best Western Delta InnEffingham
9.0 out of 10, Wonderful, (1,005 reviews)
The price is RM368
RM412 total
includes taxes & fees
24 May - 25 May

Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (1,003 reviews)
The price is RM472
RM529 total
includes taxes & fees
25 May - 26 May

Fairfield Inn & Suites Marriott Effingham
Fairfield Inn & Suites Marriott EffinghamEffingham
9.0 out of 10, Wonderful, (495 reviews)
The price is RM433
RM481 total
includes taxes & fees
14 Jun - 15 Jun

Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
9.6 out of 10, Exceptional, (858 reviews)
The price is RM393
RM424 total
includes taxes & fees
24 May - 25 May

Comfort Inn & Suites Marion I-57
Comfort Inn & Suites Marion I-57Marion
9.4 out of 10, Exceptional, (1,001 reviews)
The price is RM506
RM607 total
includes taxes & fees
15 Jun - 16 Jun

Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
8.2 out of 10, Very good, (1,008 reviews)
The price is RM304
RM337 total
includes taxes & fees
31 May - 1 Jun

The Principal Hotel
The Principal HotelColumbia
9.8 out of 10, Exceptional, (271 reviews)
The price is RM447
RM496 total
includes taxes & fees
1 Jun - 2 Jun

Best Western Plus Parkside Inn & Suites
Best Western Plus Parkside Inn & SuitesOlney
9.8 out of 10, Exceptional, (345 reviews)
The price is RM503
RM558 total
includes taxes & fees
4 Jun - 5 Jun

Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, ILO'Fallon
9.6 out of 10, Exceptional, (1,004 reviews)
The price is RM480
RM557 total
includes taxes & fees
14 Jun - 15 Jun

Country Inn & Suites by Radisson, Marion, IL
Country Inn & Suites by Radisson, Marion, ILMarion
8.6 out of 10, Excellent, (1,003 reviews)
The price is RM427
RM512 total
includes taxes & fees
31 May - 1 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southern Illinois
Apartment

Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Murphysboro Retreat w/ Deck Near Kinkaid Lake!Murphysboro
10.0 out of 10, Exceptional, (1 review)
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Photo by Southernmost Illinois Tourism Bureau
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Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon
10/10 Excellent
More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is RM246 per night from 21 Jun to 22 Jun
RM246
RM283 total
21 Jun - 22 Jun
includes taxes & fees
6.8/10 (1,010 reviews)

4 Star Hotels
4 properties
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