A forested valley with autumn foliage, a rocky cliff, and a sunset.

Best Luxury Hotels in Southern Illinois

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Check availability on Southern Illinois Luxury Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Southern Illinois luxury hotels

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

1. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,848 reviews)
"Loved the beds, and lobby bar/resturant."
United States
Richard
The price is RM450
RM508 total
includes taxes & fees
29 Nov - 30 Nov
Drury Plaza Hotel Mt. Vernon
A hotel with a covered entrance, stone pillars, and a modern design.

2. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1,002 reviews)
"Great spacious room. Breakfast was awesome and the helper was outstanding! Great food and coffee."
United States
Doug
The price is RM450
RM508 total
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express & Suites Mount Vernon by IHG
A hotel lobby with a reception desk, seating area, and a large screen TV.

3. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,092 reviews)
"Great bathroom"
United States
Bruce and Robin
The price is RM477
RM538 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Suites Mount Vernon
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.

4. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
3.0 star property
Mount Vernon
8.8 out of 10, Excellent, (729 reviews)
"Beautiful property very clean when you enter the lobby is very impressive in the staff was very helpful. Our room was clean in the morning. Breakfast was great."
United States
Susan
The price is RM407
RM460 total
includes taxes & fees
21 Nov - 22 Nov
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

5. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (721 reviews)
"Clean rooms, complimentary breakfast, great value."
United States
Ryan
The price is RM286
RM325 total
includes taxes & fees
29 Nov - 30 Nov
Quality Inn Mount Vernon, IL
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

6. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (685 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is RM564
RM632 total
includes taxes & fees
3 Nov - 4 Nov
Best Western Plus Centralia Hotel & Suites
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

7. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very good, (908 reviews)
"Nice clean and great staff"
United States
Kenneth
The price is RM519
RM584 total
includes taxes & fees
14 Nov - 15 Nov
DoubleTree by Hilton Mt. Vernon
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

8. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,000 reviews)
"Very clean and everything was perfect!"
United States
Tad
The price is RM310
RM344 total
includes taxes & fees
1 Dec - 2 Dec
SureStay Hotel by Best Western Whittington Rend Lake
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

9. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1,000 reviews)
"Everything was clean, nice hotel"
United States
Leslie
The price is RM296
RM337 total
includes taxes & fees
15 Nov - 16 Nov
Super 8 by Wyndham Mt. Vernon IL
A cozy living room with a stone fireplace, leather sofas, and a flat-screen TV.

10. Cobblestone Inn & Suites - Altamont

Cobblestone Inn & Suites - Altamont
2.5 star property
Altamont
9.6 out of 10, Exceptional, (962 reviews)
"The hotel was very clean, nice bathrooms, and very quiet."
United States
Heidi
The price is RM438
RM473 total
includes taxes & fees
29 Nov - 30 Nov
Cobblestone Inn & Suites - Altamont
A small, clean room with a microwave, a vending machine, and a table with chairs.

11. Rodeway Inn Mount Vernon, IL

Rodeway Inn Mount Vernon, IL
2.0 star property
Mount Vernon
7.2 out of 10, Good, (1,000 reviews)
"Good place to stay, we were traveling and the price was great, clean room, great staff we were very comfortable"
United States
Karalee
The price is RM266
RM303 total
includes taxes & fees
1 Nov - 2 Nov
Rodeway Inn Mount Vernon, IL
A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.

12. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,001 reviews)
"Very nice stay!!!"
United States
Steve
The price is RM442
RM495 total
includes taxes & fees
8 Nov - 9 Nov
La Quinta Inn & Suites by Wyndham Effingham
An outdoor patio area with wicker furniture, a stone pillar, and a glass-enclosed dining area.

13. Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express & Suites Salem by IHG
2.5 star property
Salem
9.4 out of 10, Exceptional, (808 reviews)
"Great location"
United States
John
The price is RM426
RM477 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Salem by IHG
An indoor swimming pool with a diving board, a changing room, and a tiled floor.

14. Days Inn by Wyndham Mount Vernon

Days Inn by Wyndham Mount Vernon
2.0 star property
Mount Vernon
6.6 out of 10, (1,001 reviews)
"Checking in was very easy and quick. I have no complaints."
United States
Howard
The price is RM259
RM295 total
includes taxes & fees
9 Nov - 10 Nov
Days Inn by Wyndham Mount Vernon
An outdoor patio area with a fire pit, seating, and a covered section.

15. Home2 Suites By Hilton Effingham

Home2 Suites By Hilton Effingham
3.0 star property
Effingham
9.6 out of 10, Exceptional, (66 reviews)
"The hotel was clean and room was fantastic in every way."
United States
Steve
The price is RM549
RM615 total
includes taxes & fees
13 Nov - 14 Nov
Home2 Suites By Hilton Effingham
A hotel room with a large bed, a desk, a chair, a TV, and a sofa.

16. Best Western Flora Inn

Best Western Flora Inn
2.5 star property
Flora
8.2 out of 10, Very good, (338 reviews)
"The staff and room were both great!"
United States
Terri
The price is RM365
RM398 total
includes taxes & fees
4 Nov - 5 Nov
Best Western Flora Inn
A hotel lobby with a reception desk, seating area with tables and chairs, and a sign for 'Quality Inn & Suites'.

17. Quality Inn & Suites Salem near I-57

Quality Inn & Suites Salem near I-57
2.5 star property
Salem
7.2 out of 10, Good, (561 reviews)
"nice place to stay at"
United States
WILLARD
The price is RM259
RM284 total
includes taxes & fees
22 Nov - 23 Nov
Quality Inn & Suites Salem near I-57
An indoor swimming pool with a clear view of the surrounding area, including a seating area with chairs and a view of the outdoors through large windows.

18. Best Western Delta Inn

Best Western Delta Inn
2.5 star property
Effingham
9.0 out of 10, Wonderful, (1,003 reviews)
"Great breakfast! The beds were so comfy! The staff was great!"
United States
Melissa Rae
The price is RM331
RM371 total
includes taxes & fees
1 Nov - 2 Nov
Best Western Delta Inn
An outdoor seating area with a fire pit, surrounded by wooden chairs and a view of a sunset over a landscaped garden.

19. Best Western Plus Parkside Inn & Suites

Best Western Plus Parkside Inn & Suites
2.5 star property
Olney
9.8 out of 10, Exceptional, (394 reviews)
"Very clean and friendly staff."
United States
Lynda
The price is RM514
RM570 total
includes taxes & fees
29 Nov - 30 Nov
Best Western Plus Parkside Inn & Suites
A spacious lobby with a beige sectional sofa, a fireplace, and a view of the outside through large glass doors.

20. Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (799 reviews)
"The property was very clean even just staying a quick overnight traveling the room felt very comfortable."
United States
Scott
The price is RM514
RM570 total
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites Effingham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Illinois Hotel Reviews

Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

8/10 Good
"friendly staff, comfortable rooms, breakfast a plus."
Rhonda 2-night trip
Posted 7 hours ago
Country Inn & Suites by Radisson, Marion, IL

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