Southeast Missouri

Travel Guide

A group of men in red uniforms with gold accents, holding rifles and wearing kilts.
A river flowing through a rocky landscape with dense green forest in the background.
A rocky river with clear water flowing over rocks.
A rocky shoreline with a calm lake and distant islands.
A river running through a forested landscape with a dirt road parallel to the river.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
The price is RM409 per night from 16 Aug to 17 Aug
RM409
RM461 total
16 Aug - 17 Aug
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,016 reviews)
"Everything about this property is 1000000/100000"

Reviewed on 9 Aug 2026

Drury Plaza Hotel Cape Girardeau Conference Center
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
The price is RM229 per night from 6 Sept to 7 Sept
RM229
RM249 total
6 Sept - 7 Sept
includes taxes & fees
Stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking and an outdoor pool. Our guests praise the helpful staff and the clean ...
Baymont Inn and Suites by Wyndham Farmington, MO
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
The price is RM468 per night from 12 Aug to 13 Aug
RM468
RM527 total
12 Aug - 13 Aug
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free Wi-Fi, free parking and 2 restaurants. Popular attractions Century Casino & Hotel Cape Girardeau ...
The Riverview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

2 out of 5
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios and climate control.
9.8/10 Exceptional! (94 reviews)
"It was a very unique and great experience! Would definitely recommend to others."

Reviewed on 9 Aug 2026

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172 Williamsville MO
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
9/10 Wonderful! (4 reviews)
"Great cabin! Better to book directly than with 3rd party, would have been cheaper."

Reviewed on 10 Aug 2026

Lake Wappapello
Johnson's Shut-ins State Park

Johnson's Shut-ins State Park

3 out of 5
148 Taum Sauk Trail Middle Brook MO
Stay at this cabin in Middle Brook. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Johnson's Shut-ins State Park and Taum Sauk ...
10/10 Exceptional! (3 reviews)
"Nice property"

Reviewed on 30 Apr 2026

Johnson's Shut-ins State Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southeast Missouri attractions

Things to do