Southeast Missouri
Travel Guide
Visit Southeast Missouri
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is RM392 per night from 25 May to 26 May
RM392
RM442 total
25 May - 26 May
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,009 reviews)
Room was clean and we had a good stay. Enjoyed complimentary breakfast and dinner. Overall would recommend.
Reviewed on 9 May 2026
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is RM229 per night from 1 Jun to 2 Jun
RM229
RM249 total
1 Jun - 2 Jun
includes taxes & fees
Stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking and an outdoor pool. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,011 reviews)
Great Job!
Reviewed on 8 May 2026
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
The price is RM435 per night from 15 May to 16 May
RM435
RM500 total
15 May - 16 May
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,014 reviews)
I loved everything. Was surprised of the amenities that they offered that evening drinks and food. For FREE
Reviewed on 10 May 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios and climate control.
9.8/10 Exceptional! (65 reviews)
Wonderful location and attentive staff. Perfect getaway.
Reviewed on 5 May 2026
Johnson's Shut-ins State Park
148 Taum Sauk Trail Middle Brook MO
Stay at this cabin in Middle Brook. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Johnson's Shut-ins State Park and Taum Sauk ...
10/10 Exceptional! (3 reviews)
Nice property
Reviewed on 30 Apr 2026
Lake Wappapello
8005 Missouri 172 Williamsville MO
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
10/10 Exceptional! (2 reviews)
Pet friendly. Family-friendly
Reviewed on 12 Apr 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Elephant Rocks State Park
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Southeast Missouri State University
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Current River State Park
Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.
Lake Wappapello
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
Big Spring
Enjoy an outing to Big Spring during your stay in Van Buren. Wander the forests and riverfront while you're in the area.
Hawn State Park
You can take time to visit Hawn State Park during your travels to Ste Genevieve. Discover the area's cafes or seek out the golf courses.
Things to do
History Tour of Pythian Castle in Springfield Missouri
RM50
per adult
90% of travellers recommend
Discovery Center of Springfield General Admission
RM67
per adult
Night Ghost Tour of Pythian Castle in Springfield Missouri
RM79
per adult
100% of travellers recommend
Explore a world of travel with Expedia
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