A stone wall with a tower, palm trees, and calm water.

Best Luxury Hotels in Southeast Jacksonville

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Jacksonville Luxury Hotels

Tonight
16 Sept - 17 Sept
Tomorrow
17 Sept - 18 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

Our top choices for Southeast Jacksonville luxury hotels

1. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
Jacksonville
RM683
RM776 total
includes taxes & fees
17 Oct - 18 Oct
Hilton Jacksonville at Mayo Clinic near Beaches

2. Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
Southside
RM505
RM574 total
includes taxes & fees
18 Sept - 19 Sept
Sheraton Jacksonville Hotel

3. Delta Hotels by Marriott™ Jacksonville Deerwood

Delta Hotels by Marriott™ Jacksonville Deerwood
Southside
RM379
RM430 total
includes taxes & fees
27 Sept - 28 Sept
Delta Hotels by Marriott™ Jacksonville Deerwood

4. Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
Ponte Vedra Beach
  • Experience beachside luxury at this 5-star coastal retreat offering a full-service spa, championship golf, and private beach access.
RM2,039
RM2,405 total
includes taxes & fees
17 Sept - 18 Sept
Ponte Vedra Inn & Club

5. Omni Amelia Island Resort & Spa

Omni Amelia Island Resort & Spa
Fernandina Beach
  • Beachfront bliss awaits at Fernandina Beach resort with pillowtop beds, Egyptian cotton sheets, and rainfall showers.
RM1,299
RM1,684 total
includes taxes & fees
20 Sept - 21 Sept
Omni Amelia Island Resort & Spa

6. Casa Monica Resort & Spa, Autograph Collection

Casa Monica Resort & Spa, Autograph Collection
St. Augustine Historic District
  • Historic resort blends spa luxury and historic charm in the heart of St. Augustine with Mediterranean dining and poolside relaxation.
RM1,099
RM1,326 total
includes taxes & fees
5 Oct - 6 Oct
Casa Monica Resort & Spa, Autograph Collection

7. Dune House Hotel & Spa

Dune House Hotel & Spa
Atlantic Beach
  • Beachfront elegance meets spa indulgence at this Atlantic Beach luxury hotel, where oceanfront views and full-service pampering await.
RM845
RM1,134 total
includes taxes & fees
14 Oct - 15 Oct
Dune House Hotel & Spa

8. Sawgrass Marriott Golf Resort & Spa

Sawgrass Marriott Golf Resort & Spa
Palm Valley
  • Beachfront Florida golf resort features private shoreline, 5 pools, and 19-room spa retreat.
RM830
RM1,039 total
includes taxes & fees
4 Oct - 5 Oct
Sawgrass Marriott Golf Resort & Spa

9. Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
Downtown Jacksonville
  • Riverfront luxury offers rooftop pool, three restaurants, and immaculate views of Jacksonville's waterfront.
RM750
RM860 total
includes taxes & fees
29 Sept - 30 Sept
Hyatt Regency Jacksonville

10. The Collector Inn - Adults Only

The Collector Inn - Adults Only
St. Augustine Historic District
RM989
RM1,205 total
includes taxes & fees
4 Oct - 5 Oct
The Collector Inn - Adults Only
View all properties

Top Southeast Jacksonville Hotel Reviews

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

10/10 Excellent
"clean rooms and great location!"
Jami 1-night trip
Posted 1 hour ago
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Baymont by Wyndham Jacksonville/Butler Blvd

Baymont by Wyndham Jacksonville/Butler Blvd

10/10 Excellent
"I enjoy staying at the Bsymont Hotel. The hotel is clean and smells fresh. The staff are pleasant and always helpful."
Valerie 1-night trip
Posted 3 hours ago
Baymont by Wyndham Jacksonville/Butler Blvd
La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd

La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd

10/10 Excellent
"Era cómodo pero un poco descuidado, el techo de la habitación se vea como si tuviese filtraciones de agua y la pintura en algunas partes estaba fea, otra cosa que me llamó la atención fue que no tienen canales de TV hispanos"
Jose 1-night trip
Posted 14 hours ago
La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd

Explore a world of travel with Expedia