𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Six Mile from RM254 (2026) - Fully Refundable Options

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Six Mile

Apartment

Pool

Waterpark

Condo

Pet friendly

Family friendly

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Six Mile hotels

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

A conference room with a large round table, multiple chairs, and a projector.

A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.

A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.

1. Holiday Inn Express & Suites Clemson by IHG

Clemson

John

RM528

RM586 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio area with a fire pit, seating, and string lights.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern restaurant with a central counter, seating area, and a TV displaying news.

2. Tru by Hilton Seneca Clemson

Seneca

Melissa

RM433

RM476 total

includes taxes & fees

18 Oct - 19 Oct

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

A lobby with seating areas, a reception desk, and a patterned wall.

3. Best Western Plus Clemson Hotel & Conference Center

Clemson

David

RM431

RM479 total

includes taxes & fees

12 Oct - 13 Oct

A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.

A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.

A hotel reception area with two reception desks, a digital screen, and a tiled floor.

4. Comfort Inn & Suites Clemson - University Area

Clemson

Yvette

RM431

RM479 total

includes taxes & fees

1 Nov - 2 Nov

A modern bar area with a menu board, bar stools, and a countertop with various items.

A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

A modern dining area with a bar, bar stools, and a patterned rug.

An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

5. Courtyard Marriott Clemson

Clemson

kim

RM422

RM469 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen area with a bar counter and seating.

A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

A vending area with snacks and beverages, including chips and soda.

A modern bar area with high stools and a poolside view.

6. Hampton Inn Clemson-University Area

Clemson

Blaise

RM449

RM498 total

includes taxes & fees

18 Oct - 19 Oct

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".

A hotel lobby with a long corridor, seating areas, and a reception desk.

A brick building with a sign reading "The Inn at Patrick Square".

7. The Inn at Patrick Square

Clemson

Jennifer

RM610

RM677 total

includes taxes & fees

11 Oct - 12 Oct

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.

8. The Shepherd Hotel Downtown Clemson

Clemson

Laurrie

RM855

RM949 total

includes taxes & fees

14 Oct - 15 Oct

A poolside area with outdoor seating and a view of a lake and forested hills.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

9. Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

Lori

RM491

RM540 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

10. Lakeside Lodge Clemson

Seneca

Lori

RM446

RM554 total

includes taxes & fees

11 Oct - 12 Oct

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

A hotel room with two beds, a desk, a television, and a clock on the wall.

A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

11. Inn @ Clemson

Clemson

Heather

RM328

RM364 total

includes taxes & fees

11 Oct - 12 Oct

A golf course with a water body, trees, and a distant view of a bridge.

An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

A golf course with a clubhouse, surrounded by dense trees and a large body of water.

A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

12. Clemson University's James F. Martin Inn

Clemson

Lilllian

RM610

RM677 total

includes taxes & fees

11 Oct - 12 Oct

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

A bar area with a counter, multiple chairs, and a display of bottles and glasses.

13. The Abernathy of Clemson

Clemson

Amy

RM658

RM731 total

includes taxes & fees

18 Oct - 19 Oct

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

A gazebo with a tiled roof and a surrounding gravel area.

A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.

14. Days Inn by Wyndham Clemson

Clemson

David

RM328

RM364 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

15. Best Western Seneca-Clemson

Seneca

Michelle

RM414

RM455 total

includes taxes & fees

12 Oct - 13 Oct

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

A reception area with a counter, chairs, and a patterned rug.

16. Hampton Inn & Suites Seneca-Clemson Area

Seneca

Lloyd

RM504

RM555 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a sectional sofa, a coffee table, a fireplace, and a clock on the wall.

A modern living room with a fireplace, a wooden wall, a bookshelf, and a dining area.

A spacious lobby with a reception desk, seating area, and a patterned rug.

A kitchen area with blue cabinets, a countertop with various food items, and overhead lighting.

17. Country Inn & Suites by Radisson, Anderson, SC

Anderson

Stephen

RM414

RM459 total

includes taxes & fees

31 Oct - 1 Nov

A modern hotel room with a large bed, a desk with a chair, a small table, and a nightstand with a lamp.

A gym with exercise equipment, a mirror, and a blue wall.

A Holiday Inn Express & Suites hotel with a modern architectural design, featuring a prominent entrance with columns and a flat roof.

A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.

18. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

Dominique

RM434

RM481 total

includes taxes & fees

8 Nov - 9 Nov

A spacious living room with a fireplace, large windows, and a flat-screen TV mounted above the mantel.

A hotel lobby with a reception desk, potted plants, and a tiled floor.

A multi-story hotel with a prominent entrance, a well-lit facade, and a parking area in front.

A spacious hotel dining area with multiple tables and chairs, a large plant, and a television on the wall.

19. Hilton Garden Inn Anderson

Anderson

David

RM449

RM498 total

includes taxes & fees

8 Nov - 9 Nov

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

20. Quality Inn Seneca US-123

Seneca

Julie

RM320

RM377 total

includes taxes & fees

11 Oct - 12 Oct

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Six Mile attractions

Keowee Springs Golf Course

Enjoy a round of golf in Six Mile at Keowee Springs Golf Course.

See properties

Mile Creek Park

Explore the great outdoors at Mile Creek Park, a lovely green space in Six Mile.

See properties

Learn more about Six Mile

Lake Keowee offers pristine waters for boating, fishing, and swimming with several public access points around Six Mile. Hikers can explore nearby Table Rock State Park's trails leading to spectacular mountain views and refreshing waterfalls.

See all hotels in Six Mile

Top Six Mile Hotel Reviews

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"Beautiful cabin, attentive hosts, and an overall great stay. I would definitely go back."

Days Inn by Wyndham Anderson

8/10 Good

"It was ok. it was old, but clean"

Quality Inn Seneca US-123

10/10 Excellent

"Clean rooms clean parking area nice staff all good"

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"lovely hotel and wonderful staff"

Comfort Suites Anderson-Clemson

10/10 Excellent

"Just right! Good breakfast."

Fairfield Inn & Suites Seneca Clemson Univ Area

10/10 Excellent

"Convenient location for doing business in seneca, and parts of clemson. The staff was wonderful. The breakfast was great."

Comfort Suites Piedmont - Greenville South

10/10 Excellent

"Stayed two nights. Very quiet. Clean room we had the king suite. Definitely will stay here again if I’m in the area. Walking distance to all food. Easy access to major highway."

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"room was clean and comfortable. bathywas a bit on the small size but doable. breakfast was normal and ok. staff was very friendly and accommodating."

The Inn at Patrick Square

10/10 Excellent

"Recommend this beautiful inn"

More cheap stays in Six Mile

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC

RM240

RM266 total

27 Oct - 28 Oct

includes taxes & fees

8.2/10 Very good! (1,003 reviews)

Inn @ Clemson

1303 Tiger Blvd Clemson SC

RM328

RM364 total

11 Oct - 12 Oct

includes taxes & fees

Quality Inn Seneca US-123

226 Hi Tech Rd Seneca SC

RM320

RM377 total

11 Oct - 12 Oct

includes taxes & fees

8/10 Very good! (757 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

RM431

RM479 total

12 Oct - 13 Oct

includes taxes & fees

8/10 Very good! (1,002 reviews)

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

RM431

RM479 total

1 Nov - 2 Nov

includes taxes & fees

8.4/10 Very good! (1,001 reviews)

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

RM446

RM554 total

11 Oct - 12 Oct

includes taxes & fees

Frequently asked questions

Where is the best place to stay in Six Mile?

Best Western Plus Clemson Hotel & Conference Center, located 8.2 mi (13.2 km) from the heart of Six Mile, is a top choice for your stay, based on our traveller data. Two other choices for your trip to the area are Lakeside Lodge Clemson and Days Inn by Wyndham Anderson. See all available top hotels, or vacation rentals in Six Mile.

If I need to cancel my hotel reservation in Six Mile, will I receive a refund?

Yes! Most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Six Mile.

What are some hotels with pools in Six Mile?

Best Western Plus Clemson Hotel & Conference Center: Hotel located near Clemson University. Offers free self parking, a seasonal outdoor pool and a 24-hour fitness centre. Lakeside Lodge Clemson and Days Inn by Wyndham Anderson are two additional hotels that offer an on-site pool. View all hotels with pools in Six Mile.

How is it staying in Six Mile?

Travellers to Six Mile will find plenty to explore and enjoy. In Six Mile, there are 77 hotels and other accommodation options to choose from. Find out more about Six Mile.

What are the top places to visit in Six Mile?

Favourite places to visit include Lake Keowee, Keowee Springs Golf Course and Mile Creek Park. You'll also find Keowee Key Golf Course and Littlejohn Coliseum in the area. Take a look at what more there is to see and do in Expedia's Six Mile guide.

What's the weather like in Six Mile?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Six Mile is 1561 mm.

Six Mile hotels from RM254

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Six Mile

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Six Mile hotels

1. Holiday Inn Express & Suites Clemson by IHG

2. Tru by Hilton Seneca Clemson

3. Best Western Plus Clemson Hotel & Conference Center

4. Comfort Inn & Suites Clemson - University Area

5. Courtyard Marriott Clemson

6. Hampton Inn Clemson-University Area

7. The Inn at Patrick Square

8. The Shepherd Hotel Downtown Clemson

9. Fairfield Inn & Suites Seneca Clemson Univ Area

10. Lakeside Lodge Clemson

11. Inn @ Clemson

12. Clemson University's James F. Martin Inn

13. The Abernathy of Clemson

14. Days Inn by Wyndham Clemson

15. Best Western Seneca-Clemson

16. Hampton Inn & Suites Seneca-Clemson Area

17. Country Inn & Suites by Radisson, Anderson, SC

18. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

19. Hilton Garden Inn Anderson

20. Quality Inn Seneca US-123

Stay near popular Six Mile attractions

Keowee Springs Golf Course

Mile Creek Park

Learn more about Six Mile

Top Six Mile Hotel Reviews

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Days Inn by Wyndham Anderson

Quality Inn Seneca US-123

The Shepherd Hotel Downtown Clemson

Comfort Suites Anderson-Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

Comfort Suites Piedmont - Greenville South

Comfort Inn & Suites Clemson - University Area

The Inn at Patrick Square

More cheap stays in Six Mile

Days Inn by Wyndham Anderson

Inn @ Clemson

Quality Inn Seneca US-123

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app