
Hotels in Santo Spirito, Florence
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Santo Spirito hotels

Mamo Florence - Bice & Krizia Apartments
Mamo Florence - Bice & Krizia Apartments
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
La Fonderia Firenze
La Fonderia Firenze
La Torre Del Cestello
La Torre Del Cestello
Drom Florence Rooms & Apartments
Drom Florence Rooms & Apartments
Hotel Firenze 2000
Hotel Firenze 2000
Ottantotto Firenze
Ottantotto Firenze
1900 Artevita
1900 Artevita
L'Antica Porta Boutique B&B
L'Antica Porta Boutique B&B
Mamo Florence - Maddalena Apartment
Mamo Florence - Maddalena Apartment
Palazzo Oliveto
Palazzo Oliveto
AdAstra Suites
AdAstra Suites
Oltrarno Classic by MMega
Oltrarno Classic by MMega
Palazzo D'Oltrarno - Residenza D'Epoca
Palazzo D'Oltrarno - Residenza D'Epoca
Residenza D'Epoca Al Numero 8
Residenza D'Epoca Al Numero 8
Le Volte by Mmega
Le Volte by Mmega
SPIRIT OF FLORENCE Boutique Rooms
SPIRIT OF FLORENCE Boutique Rooms
Torre di Bellosguardo
Torre di Bellosguardo
Appartamenti degli Artisti by Mmega
Appartamenti degli Artisti by MmegaCompare popular hotels in Santo Spirito
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Hotel Horto Convento | 9.8 Exceptional 659 reviews | View | ||||||
![]() Torre di Bellosguardo | 9.0 Wonderful 103 reviews | View | ||||||
![]() Palazzo Mannaioni Suites | 9.2 Wonderful 1,113 reviews | View | ||||||
![]() UNA Hotels Vittoria Firenze | 8.4 Very good 1,003 reviews | View | ||||||
![]() Hotel Firenze 2000 | 7.2 Good 195 reviews | View |
Where to stay in Santo Spirito

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.






























































































