Hotels in Santo Spirito, Florence

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
30 Jul - 31 Jul
Tomorrow
31 Jul - 1 Aug
This weekend
1 Aug - 3 Aug
Next weekend
8 Aug - 10 Aug

Filter by

Guest rating
Guest rating
Property class

Top 10 Hotels in Santo Spirito, Florence

Art Hotel Villa Agape
Exterior detail

Art Hotel Villa Agape

4.0 star property
9.8 out of 10, Exceptional, (1001)
"The property is very beautiful and the food is excellent "
The price is RM686
RM823 total
includes taxes & fees
19 Aug - 20 Aug
Art Hotel Villa Agape
La Fonderia Firenze
Interior

La Fonderia Firenze

9.6 out of 10, Exceptional, (160)
"Great location, wonderful staff, awesome room. Will definely stay again! "
The price is RM405
RM505 total
includes taxes & fees
24 Aug - 25 Aug
La Fonderia Firenze
Ruby Bea Hotel Florence
Bar (on property)

Ruby Bea Hotel Florence

4.0 star property
9.6 out of 10, Exceptional, (299)
"Good place to stay nowadays. "
The price is RM458
RM572 total
includes taxes & fees
6 Aug - 7 Aug
Ruby Bea Hotel Florence
IQ Hotel Firenze
Outdoor spa tub

IQ Hotel Firenze

4.0 star property
9.6 out of 10, Exceptional, (909)
"Great place nice friendly staff"
The price is RM609
RM738 total
includes taxes & fees
10 Aug - 11 Aug
IQ Hotel Firenze
Ottantotto Firenze
Garden

Ottantotto Firenze

9.6 out of 10, Exceptional, (160)
"Beautiful rooms and friendly staff "
The price is RM954
RM1,118 total
includes taxes & fees
30 Aug - 31 Aug
Ottantotto Firenze
Hotel Horto Convento
Lobby

Hotel Horto Convento

4.0 star property
9.8 out of 10, Exceptional, (543)
"I would definitely stay there again"
The price is RM624
RM754 total
includes taxes & fees
3 Aug - 4 Aug
Hotel Horto Convento
La Torre Del Cestello
Premium bedding, down duvets, in-room safe, desk

La Torre Del Cestello

9.0 out of 10, Wonderful, (194)
"Great location. Clean and comfortable rooms and super helpful and communicative staff. "
The price is RM445
RM549 total
includes taxes & fees
31 Jul - 1 Aug
La Torre Del Cestello
Palazzo Mannaioni Suites
Interior detail

Palazzo Mannaioni Suites

4.0 star property
9.2 out of 10, Wonderful, (1020)
"Great location, rooms, and lovely staff. Enjoyed our stay. "
Palazzo Mannaioni Suites
Mamo Florence - Bice & Krizia Apartments
Living area

Mamo Florence - Bice & Krizia Apartments

The price is RM440
RM985 total
includes taxes & fees
8 Aug - 9 Aug
Mamo Florence - Bice & Krizia Apartments
Mamo Florence - Maddalena Apartment
Private kitchenette

Mamo Florence - Maddalena Apartment

10.0 out of 10, Exceptional, (1)
"Fantastic top floor apartment in medieval building just beyond the Palazzo Pitti on the quieter side of the Arno. There's a cafe and a supermarket nearby, a very popular pizzeria and Santo Spirito 5 minutes away and the heart of the city is just 10 to 15 minutes walk away. The apartment had everything we needed for a family of 5, great cooking facilities and a neat and tidy bathroom. We'd definitely stay there again if we return to Florence. "
Mamo Florence - Maddalena Apartment
Mamo Florence - Cloe Apartment
Private kitchen

Mamo Florence - Cloe Apartment

10.0 out of 10, Exceptional, (2)
"This was a fantastic, spacious apartment for our family of 4. We initially had an issue with the WiFi and host communicated very well, and sent a technician to fix it very quickly. The neighborhood is wonderful - far enough away from the crowds of tourists to enjoy a quieter side of Florence, but close enough to walk 10 minutes to be in the center of all of the major tourist attractions. "
Mamo Florence - Cloe Apartment
Oltrarno Splendid
Minibar, in-room safe, soundproofing, free WiFi

Oltrarno Splendid

9.8 out of 10, Exceptional, (87)
"Great that it was completely separate and quiet - an oasis in a hot and bustling city yet very close to sights, restaurants etc."
The price is RM796
RM944 total
includes taxes & fees
3 Aug - 4 Aug
Oltrarno Splendid
Drom Florence Rooms & Apartments
Courtyard view

Drom Florence Rooms & Apartments

9.8 out of 10, Exceptional, (124)
"I loved this place and made me want to go back and stay for a while!!! The host was so nice and accommodating. This is a must book place if you are looking for Florence charm and don’t mind a 20 "
Drom Florence Rooms & Apartments
AdAstra Suites
Down duvets, in-room safe, individually decorated, desk

AdAstra Suites

9.8 out of 10, Exceptional, (213)
"Staff was absolutely wonderful!!! "
The price is RM1,076
RM1,252 total
includes taxes & fees
3 Aug - 4 Aug
AdAstra Suites
L'Antica Porta Boutique B&B
1 bedroom, in-room safe, desk, free WiFi

L'Antica Porta Boutique B&B

9.2 out of 10, Wonderful, (9)
"Nice place and really quiet during night hours, definitely a great place to stay, not that far from florence city centre"
The price is RM468
RM574 total
includes taxes & fees
11 Aug - 12 Aug
L'Antica Porta Boutique B&B
Palazzo D'Oltrarno - Residenza D'Epoca
Front of property

Palazzo D'Oltrarno - Residenza D'Epoca

9.4 out of 10, Exceptional, (37)
"Gulia & Guissepe were so friendly and accommodating during our check in and stay. Great hidden gem as the property asked all to keep silence; great to have a quiet sanctuary away from the hubbub of city life! Nice view from our #5."
Palazzo D'Oltrarno - Residenza D'Epoca
SPIRIT OF FLORENCE Boutique Rooms
1 bedroom, hypo-allergenic bedding, minibar, blackout curtains

SPIRIT OF FLORENCE Boutique Rooms

10.0 out of 10, Exceptional, (21)
"My husband and I enjoyed our stay here! Large rooms and bathrooms, wonderful location, and great staff! "
The price is RM920
RM1,071 total
includes taxes & fees
1 Aug - 2 Aug
SPIRIT OF FLORENCE Boutique Rooms
Torre di Bellosguardo
Seasonal outdoor pool

Torre di Bellosguardo

4.0 star property
9.0 out of 10, Wonderful, (97)
"Amazing hotel and Staff! Definitely coming here again during our next trip to Italy!"
The price is RM2,305
RM2,604 total
includes taxes & fees
13 Aug - 14 Aug
Torre di Bellosguardo
Hotel Firenze 2000
Front of property

Hotel Firenze 2000

2.0 star property
7.2 out of 10, Good, (167)
"The staff was very nice!"
The price is RM328
RM405 total
includes taxes & fees
28 Aug - 29 Aug
Hotel Firenze 2000
Mamo Florence - Ardiglione Apartment
Living area

Mamo Florence - Ardiglione Apartment

Mamo Florence - Ardiglione Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most.
Historic Centre of Florence map

Historic Centre of Florence

9 out of top 10 points of interest in this area

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Duomo map

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

Santa Maria Novella map

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Palazzo dei Congressi is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Uffizi Gallery showing street scenes as well as a large group of people
San Giovanni map

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Santa Croce map

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Hotel Horto Convento

Hotel Horto Convento

10/10 Excellent
"Excellent hotel and great hospitality! Highly recommend ! "
Ahmed 2-night trip
Posted 4 days ago
Hotel Horto Convento
Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8

10/10 Excellent
"I like everything in this hotel "
claudia 2-night trip
Posted 2 months ago
Residenza D'Epoca Al Numero 8

Frequently asked questions

What is Santo Spirito like?

Santo Spirito is a trendy neighbourhood known for its stunning river views. Make sure that you visit Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.

What's a favourite place to stay in Santo Spirito?

Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 9-minute walk from Ponte Vecchio, and it offers free breakfast and free WiFi. Other favourite options in the area include AdAstra Suites and Ottantotto Firenze.

How many hotels can I expect to find in the Santo Spirito area?

Expedia has 469 hotels and other accommodation options in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.

If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get top deals in Santo Spirito.

What can I see and do in this Florence neighbourhood?

Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighbourhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. Uffizi Gallery and Cathedral of Santa Maria del Fiore are some popular places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.