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Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
27 Nov - 29 Nov
In two months
8 Jan - 10 Jan
In three months
5 Feb - 7 Feb
In four months
5 Mar - 7 Mar

Our top choices for Santa Cruz holiday rentals

A modern reception area with a marble reception desk, a vertical garden, and a logo for 'GO Living & Suites'.

1. Go Living and Suites by Jalo

Go Living and Suites by Jalo
3.0 star property
El Poblado
9.2 out of 10, Wonderful, (144 reviews)
"Excellent Stay!"
United States
Esdras
The price is RM219
RM219 total
16 Nov - 17 Nov
Go Living and Suites by Jalo
A modern living room with a large window, a sofa set, a coffee table, and a potted plant.

2. Metropolitan Living by HOUSY

Metropolitan Living by HOUSY
4.0 star property
San Diego
9.0 out of 10, Wonderful, (94 reviews)
"Clean, good location, nice staff"
United States
Sau Yeng
The price is RM221
RM311 total
14 Nov - 15 Nov
Metropolitan Living by HOUSY
A multi-story building with a brick facade, multiple balconies with greenery, and a sign indicating a business or commercial use.

3. Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (301 reviews)
"Nice location; clean; helpful staff."
United States
Shivon
The price is RM292
RM292 total
18 Nov - 19 Nov
Portal del Rodeo ApartaHotel - Arkadia Mall
A multi-story hotel with a modern design, featuring a rooftop garden and a fountain.

4. Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.2 out of 10, Very good, (495 reviews)
"Very clean and a good rear view of landscape"
United States
roberto
The price is RM454
RM454 total
2 Dec - 3 Dec
Travelers Rio Verde Living Suites
A tall, modern building with the name 'KYUX' on its facade, surrounded by lush greenery and a wet street reflecting city lights.

5. Kyux by Jalo

Kyux by Jalo
4.0 star property
Laureles
9.2 out of 10, Wonderful, (210 reviews)
"Great place to stay at"
United States
Miguel
The price is RM211
RM211 total
29 Nov - 30 Nov
Kyux by Jalo
A modern bedroom with a large bed, a desk, and a balcony.

6. Hotel Moore 45

Hotel Moore 45
4.0 star property
Buenos Aires
9.0 out of 10, Wonderful, (8 reviews)
"I like the service and it’s really comfortable. And the people in their recession. Bety. Help. Take you guys. I Enjoy the State. I’m planning to Come Back. How old is go back to the hotel again!"
United States
Welinton
The price is RM97
RM97 total
16 Nov - 17 Nov
Hotel Moore 45
A reception area with a wooden desk, wicker chairs, and a patterned floor.

7. Origen Local Suites

Origen Local Suites
3.0 star property
Laureles
9.4 out of 10, Exceptional, (229 reviews)
"Hiding Gem , close to everything , 5 Stars Staff and Costumer Services!!"
United States
Luis
The price is RM229
RM229 total
18 Nov - 19 Nov
Origen Local Suites
A person in a hot tub with a can of Hatsu beer and snacks on a wooden table.

8. Laureles Grand House LGH Hotel - Anteriormente Laureles Guest House

Laureles Grand House LGH Hotel - Anteriormente Laureles Guest House
3.5 star property
Laureles
9.2 out of 10, Wonderful, (109 reviews)
"Excellent breakfast, good location "
United States
dickie
The price is RM186
RM186 total
6 Dec - 7 Dec
Laureles Grand House LGH Hotel - Anteriormente Laureles Guest House
A tall building with multiple balconies and a clear sky.

9. Hotel Santa Ana

Hotel Santa Ana
4.0 star property
El Poblado
9.0 out of 10, Wonderful, (46 reviews)
"Great location, superb staff and service and great breakfasts and food options."
United States
Juan Vicente
The price is RM180
RM180 total
23 Nov - 24 Nov
Hotel Santa Ana
A modern spa area with a hot tub, seating, and a view of a hillside village.

10. Edificio Helena

Edificio Helena
3.0 star property
Medellín
8.8 out of 10, Excellent, (75 reviews)
"Room was as expected, didn’t reward the fine print of cooling condition for the room , had a fan available in the room which helped. Appreciate the host, and the security of the building and room especially being I was a solo traveler"
United States
jocelyne
The price is RM187
RM187 total
13 Dec - 14 Dec
Edificio Helena
A modern bedroom with a large bed, a desk, and a view of a cityscape.

11. Feeling Residences

Feeling Residences
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (311 reviews)
"Great place to stay!"
United States
marcos
The price is RM365
RM365 total
14 Nov - 15 Nov
Feeling Residences
A modern building with a prominent 'N' logo, outdoor seating, and lush greenery.

12. Nomadic Boutique Living and Experience Center

Nomadic Boutique Living and Experience Center
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (50 reviews)
"Nice quite area close to everything definitely a good area to stay"
United States
Javier
The price is RM245
RM276 total
15 Nov - 16 Nov
Nomadic Boutique Living and Experience Center
A rooftop terrace with two hot tubs, a dining area with chairs and a table, and a view of a cityscape with mountains in the background.

13. Quadrato Studios

Quadrato Studios
3.0 star property
Laureles
9.4 out of 10, Exceptional, (117 reviews)
"Great hotel. Loved the views at the hot tub!"
United States
Maria Lucia
The price is RM176
RM176 total
26 Nov - 27 Nov
Quadrato Studios
A modern bedroom with a bed, a sofa, a desk, and a large window with a city view.

14. Apartment Go Living & Suites by HOUSY HOST

Apartment Go Living & Suites by HOUSY HOST
3.5 star property
El Poblado
8.4 out of 10, Very good, (468 reviews)
"Great location, secure place, quiet, private parking"
United States
CAMILO
The price is RM173
RM295 total
29 Nov - 30 Nov
Apartment Go Living & Suites by HOUSY HOST
A modern building with a curved balcony, large windows, and a stone-paved walkway.

15. Estelar Apartamentos Medellin

Estelar Apartamentos Medellin
3.5 star property
El Poblado
8.8 out of 10, Excellent, (504 reviews)
"Feel very safe and close to Sante Fe Mall"
United States
Gilbert
The price is RM440
RM440 total
12 Dec - 13 Dec
Estelar Apartamentos Medellin
A modern hotel room with a large bed, a wooden headboard, a bedside table with a lamp, and a view of the city through a large window.

16. ONCE SUITES

ONCE SUITES
3.0 star property
Envigado
10.0 out of 10, Exceptional, (3 reviews)
"Very close to everything"
United States
PAOLA
The price is RM196
RM196 total
16 Nov - 17 Nov
ONCE SUITES
A hallway with a metal railing, green plants, and a wall with a mural.

17. hotel civitas medellin

hotel civitas medellin
2.5 star property
La Candelaria
8.4 out of 10, Very good, (11 reviews)
"Staff was very friendly and attentive."
United States
Ulysses
The price is RM155
RM155 total
17 Nov - 18 Nov
hotel civitas medellin
A modern bedroom with a large bed, a bedside table, a built-in bench, a wall-mounted air conditioner, and a sliding glass door leading to an outdoor area with a table and chairs.

18. B 48 Living by B Rent

B 48 Living by B Rent
4.0 star property
Laureles - Estadio
9.8 out of 10, Exceptional, (29 reviews)
"Exceptionally friendly staff, the property is top notch. Cafe Soler is incredible."
United States
Frederick
The price is RM235
RM235 total
14 Nov - 15 Nov
B 48 Living by B Rent
Room

19. Factory Lofts

Factory Lofts
4.0 star property
Laureles - Estadio
9.6 out of 10, Exceptional, (147 reviews)
"Everything was great we will definitely be back Super clean, great location and everyone was wonderful"
United States
Michelle
The price is RM334
RM446 total
14 Nov - 15 Nov
Factory Lofts
A wooden shelf unit with multiple compartments, each containing various decorative items and a framed sign.

20. Soy Local Primavera

Soy Local Primavera
3.0 star property
El Poblado
8.2 out of 10, Very good, (132 reviews)
"Great place to stay."
United States
Yomar
The price is RM156
RM156 total
14 Nov - 15 Nov
Soy Local Primavera
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel Provenza Garden

Hotel Provenza Garden

10/10 Excellent
"Todo el servicio"
Julia 4-night trip
Posted less than an hour ago
Hotel Provenza Garden

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia.co.uk! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the wider area, you’ll find University of Antioquia and Arvi Park.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.