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Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
9 Oct - 11 Oct
In two months
20 Nov - 22 Nov
In three months
18 Dec - 20 Dec
In four months
15 Jan - 17 Jan

Our top choices for Santa Cruz holiday rentals

A person relaxing in a hot tub with a scenic view of mountains and clouds.

1. Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.4 out of 10, Exceptional, (44 reviews)
"Good location with amazing views, a bit difficult finding . But overall great place to visit."
United States
Giovanni
The price is RM232
RM290 total
1 Oct - 2 Oct
Skyline Ecoliving
A rooftop patio with tables and chairs, a bar area, and a view of the cityscape.

2. B 48 Living by B Rent

B 48 Living by B Rent
4.0 star property
Laureles - Estadio
9.8 out of 10, Exceptional, (25 reviews)
"Exceptionally friendly staff, the property is top notch. Cafe Soler is incredible."
United States
Frederick
The price is RM233
RM233 total
28 Sept - 29 Sept
B 48 Living by B Rent
A neatly made bed with a wooden headboard, a bedside table with a bottle and a glass, and a chair in a bright room with a large window.

3. Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.0 out of 10, Wonderful, (295 reviews)
"Excellent place to stay with family and friends!"
Canada
Jose
The price is RM267
RM267 total
28 Sept - 29 Sept
Portal del Rodeo ApartaHotel - Arkadia Mall
A modern hotel room with a large bed, a flat-screen TV, and a view of the city through large windows.

4. Factory Lofts

Factory Lofts
4.0 star property
Laureles - Estadio
9.6 out of 10, Exceptional, (145 reviews)
"The staff were terrific and helpful. The room was perfect in an ideal location."
United States
Amy
The price is RM283
RM394 total
30 Sept - 1 Oct
Factory Lofts
A modern kitchen with an island, bar stools, and a dining area with a sofa and coffee table.

5. Luxury Suites Prana By Cadissa

Luxury Suites Prana By Cadissa
5.0 star property
Laureles - Estadio
9.4 out of 10, Exceptional, (57 reviews)
"The hotel is Nestled in the middle of many attractions. Whick is like a quick 15 minutes from most popular attractions. The rental is more like an apartment with a full kitchen and the rooms are air conditioned."
United States
Jimmy
The price is RM364
RM530 total
28 Sept - 29 Sept
Luxury Suites Prana By Cadissa
A modern apartment with a living area, kitchenette, and large windows offering city views.

6. Kyux by Jalo

Kyux by Jalo
4.0 star property
Laureles
9.2 out of 10, Wonderful, (176 reviews)
"Excellent place to stay."
United States
Rexford
The price is RM221
RM221 total
2 Oct - 3 Oct
Kyux by Jalo
A modern living room with a large window, a sofa set, a coffee table, and a potted plant.

7. Metropolitan Living by HOUSY

Metropolitan Living by HOUSY
4.0 star property
San Diego
8.8 out of 10, Excellent, (88 reviews)
"Clean, good location, nice staff"
United States
Sau Yeng
The price is RM188
RM278 total
28 Sept - 29 Sept
Metropolitan Living by HOUSY
A modern interior with marble flooring, a reception area, and a seating area with tables and chairs.

8. Haven, A Design Hotel

Haven, A Design Hotel
4.0 star property
El Poblado
8.8 out of 10, Excellent, (734 reviews)
"Nice hotel, especially has great city view at top floor."
United States
Huijia
The price is RM410
RM410 total
1 Oct - 2 Oct
Haven, A Design Hotel
A modern bedroom with a large bed, a built-in wardrobe, a kitchen area, and a balcony with plants.

9. Living by Armoniko

Living by Armoniko
4.0 star property
Laureles
9.4 out of 10, Exceptional, (83 reviews)
"We liked the location and that they have parking on their property."
United States
Richard
The price is RM467
RM491 total
28 Sept - 29 Sept
Living by Armoniko
A bedroom with a bed, a bedside table with a plant, a sofa, and a wall with a large blue arch.

10. Hotel Moore 45

Hotel Moore 45
4.0 star property
Buenos Aires
8.6 out of 10, Excellent, (4 reviews)
"I like the service and it’s really comfortable. And the people in their recession. Bety. Help. Take you guys. I Enjoy the State. I’m planning to Come Back. How old is go back to the hotel again!"
United States
Welinton
The price is RM112
RM112 total
4 Oct - 5 Oct
Hotel Moore 45
A modern hotel room with a large bed, a nightstand, a shelf with books, and a window with a city view.

11. VENTO MOLINO

VENTO MOLINO
3.0 star property
Belen
The price is RM205
RM205 total
28 Sept - 29 Sept
VENTO MOLINO
A modern bedroom with a bed, a wooden desk, and a chair.

12. The Somos Flats Laureles

The Somos Flats Laureles
4.0 star property
Laureles
9.0 out of 10, Wonderful, (67 reviews)
"Great property and very accommodating host."
United States
Joseph
The price is RM189
RM189 total
28 Sept - 29 Sept
The Somos Flats Laureles
A modern kitchen with a central island, wooden cabinets, and a view of a cityscape through large windows.

13. GRAND BY LINARES

GRAND BY LINARES
3.0 star property
El Poblado
10.0 out of 10, Exceptional, (6 reviews)
"Amazing host and property. 10/10"
United States
Manny
The price is RM263
RM386 total
28 Sept - 29 Sept
GRAND BY LINARES
A balcony with a hot tub, wooden steps, and a potted plant.

14. Wake Living

Wake Living
4.0 star property
El Poblado
9.0 out of 10, Wonderful, (230 reviews)
"Great place"
United States
Pedro
The price is RM639
RM639 total
30 Sept - 1 Oct
Wake Living
A staircase with black railings and wooden steps, leading to a wooden wall.

15. zenia

zenia
3.0 star property
Laureles
9.4 out of 10, Exceptional, (72 reviews)
"Room was perfect, if you’re staying for a long trip, I highly recommend getting the room with the washer. Super clean and amazing location."
United States
Kirman
The price is RM121
RM121 total
28 Sept - 29 Sept
zenia
An outdoor café with tables and chairs, surrounded by potted plants and a view of buildings.

16. Laureles Grand House LGH Hotel - Anteriormente Laureles Guest House

Laureles Grand House LGH Hotel - Anteriormente Laureles Guest House
3.5 star property
Laureles
9.2 out of 10, Wonderful, (104 reviews)
"Excellent breakfast, good location "
United States
dickie
The price is RM169
RM169 total
28 Sept - 29 Sept
Laureles Grand House LGH Hotel - Anteriormente Laureles Guest House
A balcony with a city view, a seating area with a sofa and chairs, and a modern interior design.

17. Feeling Residences

Feeling Residences
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (296 reviews)
"Great place to stay!"
United States
marcos
The price is RM407
RM407 total
13 Oct - 14 Oct
Feeling Residences
A modern hotel room with a bed, a desk, a TV, and a balcony with a view.

18. Origen Local Suites

Origen Local Suites
3.0 star property
Laureles
9.4 out of 10, Exceptional, (217 reviews)
"My favorite place to stay by far! Everything is within few blocks! Bars,discos, restaurants! You named!! The staff is like family to me ! I highly recommend this hotel!!"
United States
Luis
The price is RM226
RM226 total
1 Oct - 2 Oct
Origen Local Suites
A modern spa with a rectangular hot tub, three lit candles on a wooden tray, and a beige sofa in the background.

19. Devú

Devú
5.0 star property
El Poblado
9.8 out of 10, Exceptional, (39 reviews)
"Great rooms, location of the building is a little uncomfortable for walking or taking transport due to the high speed of the road right in front."
United States
Juan
The price is RM633
RM633 total
18 Oct - 19 Oct
Devú
A modern bathroom with a bathtub, a window with a city view, and a wooden ceiling.

20. The Arena House

The Arena House
4.5 star property
El Poblado
The price is RM254
RM414 total
29 Sept - 30 Sept
The Arena House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

10/10 Excellent
"Exceeded expectations"
Kendra 1-night trip
Posted 2 hours ago
Novotel Medellín El Tesoro

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia.co.uk! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the wider area, you’ll find University of Antioquia and Arvi Park.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.