Santa Cruz hotels from RM141

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Check prices for these dates

Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Santa Cruz hotels

Restaurant
Hotel Attic 33

Hotel Attic 33

Hotel Attic 33
3.0 star property
Laureles
9.8 out of 10, Exceptional, (7)
"Was great, very recommended for a quick trip. "
United States
jorge
The price is RM198
RM198 total
11 Jan - 12 Jan 2026
Hotel Attic 33
Premium bedding, minibar, in-room safe, blackout curtains
Hotel Once22

Hotel Once22

Hotel Once22
3.0 star property
Sabaneta
9.4 out of 10, Exceptional, (25)
"Excellent new hotel, very clean and very friendly and helpful personnel."
United States
Al
The price is RM244
RM244 total
18 Dec - 19 Dec
Hotel Once22
Terrace/patio
Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
Sabaneta
9.4 out of 10, Exceptional, (242)
"great location "
United States
Juliana
The price is RM296
RM296 total
9 Jan - 10 Jan 2026
Fairfield by Marriott Medellin Sabaneta
Reception
Hotel Central Plaza Medellin

Hotel Central Plaza Medellin

Hotel Central Plaza Medellin
3.0 star property
Itagüí
8.0 out of 10, Very good, (346)
"Excellent place to stay.. I’ll be back ."
United States
Isabel
The price is RM288
RM342 total
19 Dec - 20 Dec
Hotel Central Plaza Medellin
Outdoor spa tub
Hotel Alcaravan Medellín

Hotel Alcaravan Medellín

Hotel Alcaravan Medellín
3.0 star property
Itagüí
7.8 out of 10, Good, (263)
"Staff was very helpful and caring "
United States
Gloria
The price is RM211
RM211 total
16 Dec - 17 Dec
Hotel Alcaravan Medellín
Garden
4 Sur Hotel

4 Sur Hotel

4 Sur Hotel
3.0 star property
Guayabal
9.4 out of 10, Exceptional, (199)
"Very good place to enjoy the stay"
United States
Alberto
The price is RM227
RM240 total
20 Dec - 21 Dec
4 Sur Hotel
Lobby sitting area
Hotel Nutibara

Hotel Nutibara

Hotel Nutibara
3.0 star property
La Candelaria
7.4 out of 10, Good, (538)
"Good, staff very friendley. "
United States
Robert
The price is RM343
RM343 total
10 Jan - 11 Jan 2026
Hotel Nutibara
Front of property
Hotel San Pedro del Fuerte

Hotel San Pedro del Fuerte

Hotel San Pedro del Fuerte
3.0 star property
La América
8.6 out of 10, Excellent, (301)
"The property was clean and the staff were very helpful and professional. "
Australia
Luis
The price is RM279
RM279 total
1 Jan - 2 Jan 2026
Hotel San Pedro del Fuerte
Down duvets, in-room safe, desk, laptop workspace
Firenze Lofts

Firenze Lofts

Firenze Lofts
3.0 star property
La América
9.6 out of 10, Exceptional, (372)
"Nice property and great staff"
United States
Daniel Eduardo
Firenze Lofts
Outdoor pool
Los Patios Cool Living

Los Patios Cool Living

Los Patios Cool Living
3.0 star property
Laureles
9.4 out of 10, Exceptional, (430)
"Awesome hotel and staff!"
United States
Josh
Los Patios Cool Living
Terrace/patio
Solar Hotel Casa Laureles

Solar Hotel Casa Laureles

Solar Hotel Casa Laureles
3.0 star property
Laureles
9.2 out of 10, Wonderful, (91)
"Yamilette was excellent and professional. She took great care of us in the morning for breakfast."
United States
SOAMI
The price is RM344
RM344 total
13 Dec - 14 Dec
Solar Hotel Casa Laureles
Living area
Indie Universe Creative Hotel

Indie Universe Creative Hotel

Indie Universe Creative Hotel
2.5 star property
Laureles
8.4 out of 10, Very good, (148)
"Great servace"
United States
Mark
Indie Universe Creative Hotel
Reception
The Host Medellin Only Adults

The Host Medellin Only Adults

The Host Medellin Only Adults
3.0 star property
El Poblado
10.0 out of 10, Exceptional, (10)
"Superb location with a quiet street close to the action. Walkable, safe, and the hotel itself was nice. We especially loved the included breakfast - delicious, healthy, and warm service. "
Canada
Karen
The price is RM884
RM884 total
14 Dec - 15 Dec
The Host Medellin Only Adults
Outdoor pool
La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
8.8 out of 10, Excellent, (1001)
"Breakfast, clean room and room service amazing!"
United States
Lyandra Jiliénne
The price is RM345
RM345 total
12 Jan - 13 Jan 2026
La Quinta by Wyndham Medellin
Minibar, in-room safe, desk, blackout curtains
Hotel Lagoon

Hotel Lagoon

Hotel Lagoon
3.5 star property
Rionegro
9.2 out of 10, Wonderful, (297)
"Nice property, very good food, very relaxing."
United States
Kevin
The price is RM522
RM522 total
23 Dec - 24 Dec
Hotel Lagoon
Minibar, in-room safe, individually decorated, individually furnished
Moa Select

Moa Select

Moa Select
3.0 star property
Laureles
9.2 out of 10, Wonderful, (194)
"Great place"
United States
Cody
The price is RM235
RM235 total
12 Jan - 13 Jan 2026
Moa Select
Exterior
Holiday Inn Express Medellin by IHG

Holiday Inn Express Medellin by IHG

Holiday Inn Express Medellin by IHG
3.0 star property
El Poblado
8.8 out of 10, Excellent, (920)
"Great!"
United States
Kelly
The price is RM378
RM439 total
11 Jan - 12 Jan 2026
Holiday Inn Express Medellin by IHG
Restaurant
Hunters By Jalo

Hunters By Jalo

Hunters By Jalo
3.0 star property
El Poblado
9.2 out of 10, Wonderful, (192)
"Really nice hotel! "
United States
IBRAHIM
The price is RM310
RM310 total
14 Dec - 15 Dec
Hunters By Jalo
Terrace/patio
Landmark Hotel

Landmark Hotel

Landmark Hotel
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (226)
"Very nice hotel. "
United States
Andres F.
The price is RM510
RM510 total
17 Dec - 18 Dec
Landmark Hotel
Sun deck
The Morgana Poblado Suites Hotel

The Morgana Poblado Suites Hotel

The Morgana Poblado Suites Hotel
3.5 star property
Buenos Aires
8.8 out of 10, Excellent, (860)
"Staff always super nice and very approachable"
United States
Hector
The Morgana Poblado Suites Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals

10/10 Excellent
"Todo bien"
MARILUZ 2-night trip
Posted 16 hours ago
V Grand Hotel, a member of Radisson Individuals

More cheap stays in Santa Cruz

Hotel Villanueva Comfort

Hotel Villanueva Comfort

57-12 Cra. 49 Medellín Antioquia
The price is RM141 per night from 15 Dec to 16 Dec
RM141
RM141 total
15 Dec - 16 Dec
8.6/10 Excellent! (29 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 5.9 mi (9.4 km) from the heart of Santa Cruz, Heiss Hotel By Jalo is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Hotel Dorado La 70 and Calle Flora Hotel by Jalo. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
La Gracia Hotel & Spa: This holiday home rental outside of Santa Cruz offers a terrace, a garden and free WiFi to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is staying in Santa Cruz like?
Visitors will definitely enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 3 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Places to visit in the wider area include Medellin Botanical Garden, Arvi Park and Antioquia Museum. You'll also find Botero Plaza and Atanasio Giradot Stadium in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How can I get around Santa Cruz?
Make your way to Andalucía MetroCable Station for metro travel. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the seasonal weather in Santa Cruz?
The hottest months are usually August and July, with an average temperature of 19°C, while the coldest months are December and January, with an average of 18°C. The rainiest months in Santa Cruz are May, April, October and November, with each month seeing an average of 406 mm of rainfall.

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