Best Luxury Hotels in Santa Cruz Island

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Cruz Island Luxury Hotels

Our top choices for Santa Cruz Island luxury hotels

Exterior
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
4.5 star property
Puerto Ayora
9.2 out of 10, Wonderful, (87)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"
United States
Jonathan
The price is RM2,694
RM2,969 total
17 Dec - 18 Dec
Finch Bay Galapagos Hotel
Bar (on property)
Royal Palm Galapagos, Curio Collection Hotel by Hilton

Royal Palm Galapagos, Curio Collection Hotel by Hilton

Royal Palm Galapagos, Curio Collection Hotel by Hilton
4.5 star property
Santa Rosa
9.2 out of 10, Wonderful, (52)
"The best part about staying at Royal Palms Galapagos was the staff. They were all friendly and helpful, making their best effort to make our stay enjoyable. They remembered our dietary restrictions and would point out if a dish had food we couldn’t eat. The facilities were very nice, and cleaned by friendly staff. The property grounds were serene and lovely. We thoroughly enjoyed our visit and would definitely choose the Royal Palms again."
United States
Laureen
The price is RM980
RM1,078 total
20 Dec - 21 Dec
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Front of property
Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (122)
"Beautiful property "
Canada
David
The price is RM893
RM982 total
16 Dec - 17 Dec
Blu Galapagos Sustainable Waterfront Lodge
Terrace/patio
Hotel Cucuve

Hotel Cucuve

Hotel Cucuve
4.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (268)
"Very nice location, friendly staff "
Italy
davide
The price is RM901
RM992 total
13 Jan - 14 Jan 2026
Hotel Cucuve
Breakfast, dinner served; local and international cuisine, sea views
Ikala Galapagos Hotel

Ikala Galapagos Hotel

Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (126)
"Nice clean hotel"
United States
Marco
The price is RM1,005
RM1,106 total
14 Dec - 15 Dec
Ikala Galapagos Hotel
Free minibar, in-room safe, desk, free WiFi
Hotel Santa Fe

Hotel Santa Fe

Hotel Santa Fe
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (14)
"Beautiful hotel, with amazing staff, and great location "
United States
Steven
The price is RM760
RM836 total
15 Dec - 16 Dec
Hotel Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Cruz Island Hotel Reviews

Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

10/10 Excellent
"I was very pleased with Blu Galapagos. The rooms were very clean, great view, very helpful staff. My only recommendation would be to not use the tour company in the hotel. I booked a tour after being very specific in what I wanted to see. I was assured it was possible but once I arrived the tour guide explained there was not enough time within my limited time to see what I came for. Very disappointed. Was not offered any refund or other compensation. The tour was not inexpensive and feel I was completely lied to and intentionally misled. "
Donna 4-night trip
Posted 3 months ago
Blu Galapagos Sustainable Waterfront Lodge
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

10/10 Excellent
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"
Jonathan 4-night trip
Posted 1 year ago
Finch Bay Galapagos Hotel

Explore a world of travel with Expedia