Santa Cruz hotels from RM183

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Santa Cruz hotels

Sun Hotel

3.5 star property
8.2 out of 10, Very good, (303)
"Staff are friendly and helpful! Great landing spot after a long flight (it’s just 5 mins from airport). "
Sun Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (245)
"Location, surrounding, quietness, good service "
The price is RM318
RM318 total
15 Aug - 16 Aug
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
9.0 out of 10, Wonderful, (323)
"Always an amazing hotel "
The price is RM593
RM593 total
13 Aug - 14 Aug
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Novotel Santa Cruz De La Sierra

5.0 star property
9.2 out of 10, Wonderful, (95)
"Nice hotel, modern, with pool, good restaurant. Would stay here again without no doubt. "
The price is RM445
RM445 total
7 Aug - 8 Aug
Novotel Santa Cruz De La Sierra

Hotel LP Santa Cruz Centro

3.0 star property
8.0 out of 10, Very good, (280)
"Clean, friendly staff"
Hotel LP Santa Cruz Centro

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (394)
"Great Hotel, had a great time ."
The price is RM593
RM593 total
19 Aug - 20 Aug
Camino Real Hotel

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
9.0 out of 10, Wonderful, (191)
"Our stay was comfortable and the service was great!"
The price is RM505
RM505 total
8 Aug - 9 Aug
Marriott Santa Cruz de la Sierra Hotel

Terranova Suites

3.5 star property
8.0 out of 10, Very good, (90)
"The pictures of the property have to be from a decade ago. This place it is dirty and in poor shape. "
The price is RM206
RM206 total
28 Jul - 29 Jul
Terranova Suites

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (77)
"Beautiful hotel"
The price is RM393
RM393 total
13 Aug - 14 Aug
Swissôtel Santa Cruz De La Sierra

TRYP by Wyndham Santa Cruz

4.0 star property
9.2 out of 10, Wonderful, (125)
"It should have a dinning room for meals not just breakfast "
The price is RM461
RM461 total
24 Jul - 25 Jul
TRYP by Wyndham Santa Cruz

Casa Vida

3.5 star property
9.0 out of 10, Wonderful, (2)
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"
Casa Vida

Hotel Continental Park

3.0 star property
8.6 out of 10, Excellent, (24)
The price is RM291
RM291 total
24 Jul - 25 Jul
Hotel Continental Park

Ibis Santa Cruz DE LA Sierra

3.0 star property
9.6 out of 10, Exceptional, (46)
"Basic hotel with very friendly staff. The staff is superb Very nice neighborhood!!!nice shopping and great restaurants !"
The price is RM183
RM183 total
7 Aug - 8 Aug
Ibis Santa Cruz DE LA Sierra

Hotel Cortez

3.5 star property
9.0 out of 10, Wonderful, (110)
"I love the pool and garden area and ALL of the staff are so friendly and helpful "
The price is RM488
RM488 total
25 Jul - 26 Jul
Hotel Cortez

Casa Por Temporadas

2.0 star property
10.0 out of 10, Exceptional, (1)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
The price is RM402
RM402 total
24 Jul - 25 Jul
Casa Por Temporadas

Cosmopolitano Hotel Boutique

3.5 star property
9.2 out of 10, Wonderful, (121)
"Top class and 5 Stars. Attentive , caring staff and wonderful food ! A great location, only 10 minutes from 24 Septiembre plaza. Thoroughly recommend."
Cosmopolitano Hotel Boutique

Buganvillas Hotel Suites & Spa

4.0 star property
7.4 out of 10, Good, (92)
"El Hotel es bonito, pero tienen su mobiliario bastante descuidado en la piscina y el servicio no es nada bueno. Tardan mucho para cosas simples y la piscina no está temperada como solía estar, han desmejorado mucho"
Buganvillas Hotel Suites & Spa

Hotel BY Armonia SCZ

3.0 star property
8.4 out of 10, Very good, (7)
Hotel BY Armonia SCZ

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
9.0 out of 10, Wonderful, (72)
"Good price, great hotel!"
Premium Suites Deluxe Aparthotel Equipetrol

Chairú Eco Hotel

3.5 star property
9.4 out of 10, Exceptional, (37)
"Nice and clean hotel "
Chairú Eco Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:1 Aug - 3 Aug
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz
Hamacas map

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Hotels near Santa Cruz Attractions

Cine Center

Cine Center

You can make plans for a show at Cine Center on your trip to Santa Cruz. While in the area, you can find time to visit its shops.

Learn more about Santa Cruz

Santa Cruz awaits: its cafes, zoo, cathedral and more!

San Lorenzo Cathedral which includes a park

Top Santa Cruz Hotel Reviews

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is a favourite with Expedia customers. This hotel offers a restaurant and free parking. Reviews from our site also recommend Alfonsina Hotel Boutique by Inboccaluppo and Chairú Eco Hotel as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best holiday rentals that Santa Cruz has to offer?

Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop and a microwave. Kick off your shoes and enjoy yourself with a private garden and a selection of games. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What's the best budget-friendly accommodation in Santa Cruz?

Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Residencial Ikandire II and Urubo Suite - Hostel. View all budget hotels in Santa Cruz.

What's the best family accommodation in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.

What's the best accommodation for a romantic holiday in Santa Cruz?

Buganvillas Hotel Suites & Spa is a favourite 4-star hotel for couples, and features in-room massages and rainfall showerheads. See all romantic hotels in Santa Cruz.

What's the best LGBTQ-friendly accommodation in Santa Cruz?

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's the best dog-friendly accommodation option in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include Hotel LP Santa Cruz Centro and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.

What's the best luxury accommodation option in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.

What's the best boutique-style hotel in Santa Cruz?

Senses Boutique Hotel is a favourite 3.5-star hotel with our travellers looking for stylish accommodation, and features 52 guestrooms, 3 restaurants and a bar.

What are some accommodation options with pools in Santa Cruz?

Sun Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. A couple of other options that feature an on-site pool include Buganvillas Hotel Suites & Spa and Yotau All Suites Hotel. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

What's it like to stay in Santa Cruz?

Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 266 hotels and other accommodation options to choose from. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Cultural venues include Cine Center, Sacred Art Museum and Franco Aleman Cultural Center. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Catedral de Santa Cruz might be worth a visit. The picturesque setting of Guembe Biocenter and Lomas de Arena Regional Park exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

How should I get around Santa Cruz?

If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the weather like in Santa Cruz?

The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.