Santa Clara hotels from RM226

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4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

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Top 10 trending Santa Clara hotels

47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1002)
"Great location. Lovely lobby. Wonderful and abundant breakfast. Only drawback for us was our room -- it was a family room on the top floor and window was low, hard to see outside. Also a little loud from room next door. "
United States
Sara
The price is RM1,138
RM1,252 total
includes taxes & fees
7 Dec - 8 Dec
Central Hotel Panama Casco Viejo
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

4.0 star property
Casco Viejo
9.6 out of 10, Exceptional, (194)
"Beautiful room Good location"
United States
Karla
The price is RM934
RM1,028 total
includes taxes & fees
17 Dec - 18 Dec
La Concordia Boutique Hotel
Reception
Hotel Coral Suites

Hotel Coral Suites

3.5 star property
Bella Vista
9.0 out of 10, Wonderful, (1000)
"Great place for the price. "
United States
Ryan
The price is RM274
RM301 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Coral Suites
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1011)
"I loved everything about my stay "
United States
Stephanie
The price is RM739
RM813 total
includes taxes & fees
18 Dec - 19 Dec
Waldorf Astoria Panama
3 outdoor pools, pool umbrellas, pool loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5.0 star property
Veracruz
8.0 out of 10, Very good, (1000)
"Clean rooms , friendly staff , had great experience "
United States
Saro
The price is RM686
RM755 total
includes taxes & fees
16 Dec - 17 Dec
The Westin Playa Bonita Panama
Exterior
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1018)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is RM317
RM349 total
includes taxes & fees
9 Dec - 10 Dec
TRYP by Wyndham Panamá Centro
Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4.0 star property
Tocumen
8.6 out of 10, Excellent, (1856)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is RM515
RM566 total
includes taxes & fees
18 Dec - 19 Dec
Riande Aeropuerto Hotel & Casino
Aerial view
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

3.5 star property
Colon
7.8 out of 10, Good, (661)
"Beautiful place to stay for one night. A little over priced for Panama but the service and the food were excellent. "
Canada
Dan
The price is RM515
RM566 total
includes taxes & fees
17 Dec - 18 Dec
Gamboa Rainforest Reserve
Front of property – evening/night
Principe Hotel and Suites

Principe Hotel and Suites

3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1590)
"Great hotel, location, food. Highly recommend the sushi restaurant next door.. One of the best ever. "
United States
Lakshmin
The price is RM206
RM226 total
includes taxes & fees
20 Dec - 21 Dec
Principe Hotel and Suites
Outdoor pool
Ramada Panama Centro Via Argentina

Ramada Panama Centro Via Argentina

3.0 star property
Bella Vista
7.4 out of 10, Good, (267)
"Hotel staff and rooms were good , great location "
United States
Cornelly
The price is RM245
RM269 total
includes taxes & fees
4 Jan - 5 Jan 2026
Ramada Panama Centro Via Argentina
Exterior
Aloft Panama

Aloft Panama

3.5 star property
San Francisco
8.8 out of 10, Excellent, (889)
"The staff was very friendly, rooms were clean and modern."
United States
Greg
The price is RM456
RM501 total
includes taxes & fees
16 Dec - 17 Dec
Aloft Panama
Front of property
Novotel Panama City

Novotel Panama City

4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1028)
"Room very clean, nice staffs and good location "
United States
Hayden
The price is RM379
RM417 total
includes taxes & fees
9 Dec - 10 Dec
Novotel Panama City
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1010)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is RM740
RM814 total
includes taxes & fees
4 Jan - 5 Jan 2026
Bristol Panama, a Registry Collection Hotel
Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (635)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is RM739
RM813 total
includes taxes & fees
6 Dec - 7 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 star property
Bella Vista
7.6 out of 10, Good, (689)
"The breakfast was great, I love the pool."
United States
Estefani
The price is RM228
RM251 total
includes taxes & fees
8 Dec - 9 Dec
Hospedium Princess Hotel Panama
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1002)
"Conveniently located near the airport and major shopping outlets."
United States
Greg
The price is RM435
RM478 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Panama Metromall
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (257)
"Great location!"
United States
Erik
The price is RM1,311
RM1,442 total
includes taxes & fees
7 Dec - 8 Dec
Hotel La Compañía Casco Antiguo
Private kitchen
Mahogany Suites

Mahogany Suites

2.0 star property
Rousseau
10.0 out of 10, Exceptional, (1)
"Todo ok"
Colombia
Juan
The price is RM375
RM413 total
includes taxes & fees
4 Jan - 5 Jan 2026
Mahogany Suites
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very good, (1246)
"Its a very beautiful hotel with view and very good breakfast "
United States
Patrick
The price is RM571
RM628 total
includes taxes & fees
23 Dec - 24 Dec
Megapolis Hotel Panamá
Outdoor pool, pool loungers
Hampton by Hilton Panama

Hampton by Hilton Panama

3.0 star property
Bella Vista
7.8 out of 10, Good, (1008)
"The hotel is good for the price , the lobby didn’t have any air conditioning,also the rooms where clean but needed to be updated , the breakfast buffet had multiple choices and it was very good . The hotel is in great location near walking distance to restaurants and stores . I will stay again. "
United States
Yusneilys amores
The price is RM296
RM326 total
includes taxes & fees
12 Dec - 13 Dec
Hampton by Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Clara attractions

Culebra Cut

You can learn about the history of Santa Clara when you stop by Culebra Cut. Visit the casinos and top-notch restaurants in this walkable area.
See properties

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history and more!

See all hotels in Santa Clara
Adobe

Top Santa Clara Hotel Reviews

Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Excellent stay. Wonderful staff, good location and excellent breakfast"
Michael 14-night trip
Posted 10 hours ago
Decapolis Hotel Panama City

More cheap stays in Santa Clara

Arcadia Condo Suites

Arcadia Condo Suites

Calle rio mar Panama City Panamá Province
The price is RM285 per night from 21 Dec to 22 Dec
RM285
RM504 total
21 Dec - 22 Dec
includes taxes & fees
9.2/10 Wonderful! (144 reviews)

Frequently asked questions

What's the best place to stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Las Americas Golden Tower Panama and Waldorf Astoria Panama. See all available top hotels, or vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer, including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1611 hotels and other accommodation options in the surrounding area. Find out more about Santa Clara.
What should I do while I'm visiting Santa Clara?
A favourite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Clara guide.
What's the weather like in Santa Clara?
The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Santa Clara are July, August, November and October, with each month seeing an average of 283 mm of rainfall.

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