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Sant'Isidoro Vacation Rentals

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Our top choices for Sant'Isidoro holiday rentals

Domus Dejana

Gallipoli Historic Center
10.0 out of 10, Exceptional, (16)
"Best breakfast and place to have it on the rooftop "
Sweden
Lars Goran
Domus Dejana

Central Plaza

Lecce Historic Center
7.8 out of 10, Good, (71)
"Great location, fantastic price. Hard to find but not impossible."
United States
Bruce
Central Plaza

Fourseasons

Lecce
7.6 out of 10, Good, (34)
"Very good"
Mexico
Horacio
The price is RM193
RM227 total
includes taxes & fees
10 Dec - 11 Dec
Fourseasons

Hotel L'Uomo e il Mare

Gallipoli
9.0 out of 10, Wonderful, (18)
"Great staff easy to find the hotel too"
Canada
david
Hotel L'Uomo e il Mare

La Collina di Montegrappa - Suites with Heated Private Pool - Suites with Shared Pool

Tuglie
10.0 out of 10, Exceptional, (2)
"Sehr gepflegte Anlage. Die Hausdame spricht sehr gut Englisch, ist unglaublich hilfsbereit, herzlich und ganz reizend. Das Deluxe Studio ist fantastisch, die Terasse ist riesig. Da es eine Spülmaschine gibt, wäre etwas mehr Besteck wünschenswert. Wir hatten nur 3 Sets. Hinter der Anlage liegt eine Firma mit LKWs die sehr früh mit den Arbeiten beginnt, was durchaus nervig sein kann. Da wir tagsüber unterwegs waren, war uns das egal, wer den Tag auf der sehr schönen Terrassen verbringen will,...
Germany
Nirwana
The price is RM235
RM1,312 total
includes taxes & fees
11 Dec - 12 Dec
La Collina di Montegrappa - Suites with Heated Private Pool - Suites with Shared Pool

Relais Il Mignano

Centro Storico
8.4 out of 10, Very good, (28)
"È stato meraviglioso soggiornare da voi❣️ Tutto bellissimo, pulitissimo ed elegante 😍 la colazione ricca e deliziosa......le torte di Luana insuperabili💞"
Italy
Raffaella
Relais Il Mignano

Casa dei Mercanti Town House

Lecce Historic Center
9.6 out of 10, Exceptional, (21)
"This place was great! Near to everything and super comfortable. Our host Franzi was amazing!"
United States
Daniela
Casa dei Mercanti Town House

Suite Porta Terra

Gallipoli Historic Center
6.8 out of 10, (8)
"La réception se trouve à 10min a pied de l hôtel Nous avons pas été prévenu à l’avance. Le logement est sombre, donne sur une mini cour intérieure/terrasse partagée avec un autre logement et où sont entreposés un ancien meuble de salle de bain et une échelle. Il y avait même une vielle assiette en plastique. Pour finir, la montée de escalier est très penture et étroite, pas du tout pratique avec des valises Autrement la chambre est correcte"
France
Florian
The price is RM286
RM315 total
includes taxes & fees
10 Dec - 11 Dec
Suite Porta Terra

Villa Ghetta Country House

Leverano
8.0 out of 10, Very good, (7)
"Très cher pour ce que c est"
France
brigitte
Villa Ghetta Country House

Royal House

Copertino
9.4 out of 10, Exceptional, (11)
"the apartment was very clean, spacious, modern and comfortable. A kitchenette forms part of the apartment. Massimo the owner, was very friendly and helpful. The apartment is only a few minutes walk from the historical centre. The only downside that we were at the second floor and there is no lift. A big plus Massimo's father runs the shop next door to the apartments and he is there from very early in the morning till late in the evening. "
Ireland
Paul
The price is RM255
RM280 total
includes taxes & fees
17 Dec - 18 Dec
Royal House

Lo Studio di viale Lo Re Camere & Caffè

Lecce Historic Center
9.2 out of 10, Wonderful, (11)
"We booked this property last minute, since our initial reservation at another hotel was cancelled by the host and left us stranded. What a gem! It was very clean, modern, friendly staff who allowed early check in, and excellent location to walk around Lecce. Would highly recommend. "
Canada
Diana
Lo Studio di viale Lo Re Camere & Caffè

Villa Neviera - Wine Resort and Spa

San Donaci
10.0 out of 10, Exceptional, (1)
The price is RM403
RM443 total
includes taxes & fees
7 Jan - 8 Jan 2026
Villa Neviera - Wine Resort and Spa

SA Suites

Trepuzzi
9.6 out of 10, Exceptional, (5)
"Amazing stay at this Masseria which exceeded all expectations. From the beautiful interiors and location, to the delicious breakfast and dinner cooked by the hosts, our stay was fantastic. Nick and Anja are incredible hosts and the Masseria is even more beautiful in real life. We loved waking up among the beautiful tree groves and enjoying the days by the pool. The rooms are big and beautifully furnished. In the evenings, the hosts treated us to a delicious dinner and signature cocktails on...
United Kingdom
Marius
The price is RM767
RM844 total
includes taxes & fees
8 Jan - 9 Jan 2026
SA Suites

B&B CENTRALE

Gallipoli
6.0 out of 10, (1)
"Hôtel "
France
clement
The price is RM218
RM240 total
includes taxes & fees
7 Jan - 8 Jan 2026
B&B CENTRALE

LE DUE DIMORE

Collepasso
The price is RM265
RM291 total
includes taxes & fees
30 Dec - 31 Dec
LE DUE DIMORE

Dimore di Lecce

Lecce Historic Center
9.4 out of 10, Exceptional, (20)
"Location great !"
Canada
Nick
The price is RM392
RM445 total
includes taxes & fees
11 Dec - 12 Dec
Dimore di Lecce

Mediterranee Suite

Lecce Historic Center
9.2 out of 10, Wonderful, (13)
"Lovely little suite, well located , a great place to stay for a short break."
United Kingdom
Michaela
The price is RM321
RM363 total
includes taxes & fees
7 Jan - 8 Jan 2026
Mediterranee Suite

La Lanterna

Martano
10.0 out of 10, Exceptional, (2)
"Hotel in zona ottimale per il raggiungimento di tutte le località salentine sia dalla parte ionica che Adriatica. Molto pulito, camere spaziose e ben attrezzate, personale estremamente gentile ed accogliente."
Italy
PEDRINAZZI
La Lanterna

La Vetrana Rooms

Avetrana
8.0 out of 10, Very good, (1)
"Ottima struttura."
Italy
pietro
The price is RM447
RM491 total
includes taxes & fees
15 Dec - 16 Dec
La Vetrana Rooms

IL RIFUGIO DEI TEMPLARI

Lecce Historic Center
10.0 out of 10, Exceptional, (3)
"Alessandra is absolutely amazing! The check-in was easy and Alessandra was super helpful. The place is very clean, AC works great. I loved my stay there. "
United States
Vera
The price is RM419
RM475 total
includes taxes & fees
12 Dec - 13 Dec
IL RIFUGIO DEI TEMPLARI
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sant'Isidoro Hotel Reviews

Find out more about Sant'Isidoro

Search for holiday rentals in Sant'Isidoro on Expedia.co.uk! You can easily find your home rentals, villas, holiday apartments in Sant'Isidoro using one of the methods below:

  • View our selection of featured holiday rentals in Sant'Isidoro
  • Use the map to find apartments and other holiday homes in the Sant'Isidoro neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Sant'Isidoro while they last

Look no further and take a look at our great range of rental properties in Sant'Isidoro!

Frequently asked questions

Can I find holiday rentals in Sant'Isidoro?

Yes, there are holiday rentals close to the most popular sights in Sant'Isidoro, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Sant'Isidoro has to offer?

Kalinifta Rooms Apartment: This holiday home rental outside of Sant'Isidoro is located on the waterfront, and has a private balcony, a rooftop terrace and a BBQ to put you at ease in your new surroundings. Kitchen amenities such as a fridge and kitchenware can make your holiday run smoothly. You and your friends and family can relax into your holiday with amenities such as a garden.

How many holiday rentals will I find in Sant'Isidoro?

Expedia has 32 holiday rentals for your stay in Sant'Isidoro.

What’s there to see and do in Sant'Isidoro?

Spiaggia di Sant'Isidoro and Ionian Sea are a couple of lovely local spots to get outside and enjoy nature. While here, Porto Selvaggio and Palude del Capitano Regional Nature Park and Lido dell' Ancora are other places worth a visit.

What’s a holiday rental in Sant'Isidoro like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Sant'Isidoro. Holiday rentals offer amenities such as patios, hot tubs and fire pits so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a holiday rental can provide a sense of security away from shared hotel lifts and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a holiday rental than in a hotel, which makes a holiday rental a great option for family gatherings.