Hotels in Sanctuary, Sanibel

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Our top choices for Sanctuary hotels

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
20.2 km from Sanctuary
9.6 out of 10, Exceptional, (222 reviews)
"Excellent communication with the staff. Nice room. Great location. Beautiful views. "
United States
Fred
The price is RM182
RM472 total
includes taxes & fees
28 Jan - 29 Jan
Matlacha on Shoreview

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
18.1 km from Sanctuary
9.0 out of 10, Wonderful, (1,004 reviews)
"Amazing room and view. Great place to stay/vacation. Would come back over and over again. "
United States
Frank
The price is RM928
RM1,197 total
includes taxes & fees
8 Feb - 9 Feb
The Westin Cape Coral Resort At Marina Village

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
25.2 km from Sanctuary
5.8 out of 10, (1,004 reviews)
"Beautiful place "
United States
Blaine
The price is RM329
RM395 total
includes taxes & fees
24 Jan - 25 Jan
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,182 reviews)
"Is great place to stay."
United States
Anastassia
The price is RM513
RM571 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.8 out of 10, Excellent, (1,002 reviews)
"The staff were great, the hotel was excellent and we had a wonderful trip!"
United States
Dana
The price is RM615
RM686 total
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1,224 reviews)
"Nice place for the price. "
United States
Adam
The price is RM690
RM769 total
includes taxes & fees
27 Jan - 28 Jan
Dolphin Key Resort

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
8.8 km from Sanctuary
9.6 out of 10, Exceptional, (150 reviews)
"Nice new rooms and great outdoor seating on the waterway, we saw lots of manatees "
United States
Ellen
The price is RM1,024
RM1,277 total
includes taxes & fees
1 Feb - 2 Feb
Off the Charts Inn & Out Island Resort

White Orchid Apartments

White Orchid Apartments
2.0 star property
20 km from Sanctuary
8.0 out of 10, Very good, (49 reviews)
"Place was nice and private. "
United States
Dawn
The price is RM397
RM574 total
includes taxes & fees
26 Jan - 27 Jan
White Orchid Apartments

Summerwind Studios

Summerwind Studios
2.0 star property
22.6 km from Sanctuary
8.0 out of 10, Very good, (11 reviews)
"Very clean and roomy. Quiet neighborhood. Loves the shower; so relaxing. Only complaint is that we could have used some drinking glasses. I would stay here again. "
United States
Micki
The price is RM389
RM565 total
includes taxes & fees
26 Jan - 27 Jan
Summerwind Studios

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,552 reviews)
"Sweet staff, amazing beach access, pool, restaurant on site. Good value and great stay!"
United States
Freda
The price is RM1,126
RM1,356 total
includes taxes & fees
25 Jan - 26 Jan
Sanibel Island Beach Resort

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
22.7 km from Sanctuary
8.2 out of 10, Very good, (17 reviews)
"Everything was great, will definitely be coming back"
United States
Ruben
The price is RM377
RM551 total
includes taxes & fees
26 Jan - 27 Jan
TriLuxe Inn & Studios

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.4 out of 10, Very good, (1,005 reviews)
"Great location "
United States
Lance
The price is RM1,570
RM1,851 total
includes taxes & fees
25 Jan - 26 Jan
Marriott Sanibel Harbour Resort & Spa

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
25.4 km from Sanctuary
7.4 out of 10, Good, (1,002 reviews)
"Great place to stay."
United States
David
The price is RM470
RM524 total
includes taxes & fees
1 Feb - 2 Feb
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1,000 reviews)
"Great stay "
United States
Brandon
The price is RM658
RM733 total
includes taxes & fees
29 Jan - 30 Jan
Doubletree by Hilton Fort Myers at Bell Tower Shops

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,003 reviews)
"Great stay"
United States
Erica
The price is RM702
RM782 total
includes taxes & fees
25 Jan - 26 Jan
Hilton Garden Inn Ft Myers

Sanibel Inn

Sanibel Inn
3.0 star property
East End, 13.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,004 reviews)
"Great location"
United States
Sandra
The price is RM1,433
RM1,856 total
includes taxes & fees
3 Feb - 4 Feb
Sanibel Inn

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.6 out of 10, Excellent, (1,001 reviews)
"Staff was great!"
United States
Jeff
The price is RM739
RM823 total
includes taxes & fees
30 Jan - 31 Jan
Residence Inn by Marriott Fort Myers Sanibel

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (808 reviews)
"Good location "
United States
Lynn
The price is RM468
RM522 total
includes taxes & fees
1 Feb - 2 Feb
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Island Inn

Island Inn
3.5 star property
West End, 9.6 km from Sanctuary
9.4 out of 10, Exceptional, (1,127 reviews)
"Everything was wonderful."
United States
Walter
The price is RM1,126
RM1,255 total
includes taxes & fees
27 Jan - 28 Jan
Island Inn

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
30.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,003 reviews)
"Clean and tidy hotel, friendly staff and the breakfast is excellent. 4th time we have stayed here in last 15 months"
United Kingdom
Adam
The price is RM778
RM867 total
includes taxes & fees
31 Jan - 1 Feb
Homewood Suites by Hilton - Fort Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Frequently asked questions

What is Sanctuary like?
Travellers are sure to enjoy a stay in Sanibel's Sanctuary neighbourhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels will I be able to find in the Sanctuary area?
With 11 Expedia hotels and other accommodation options in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals available in Sanctuary.
What is there to do around this Sanibel neighbourhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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