Medical Center District

San Antonio

River walk in San Antonio
Tourists River Walk San Antonio Texas
Riverboat on the San Antonio River Walk, San Antonio, Texas, United States of America.
River walk in San Antonio
SanAntonio_SouthTexasMedicalCenter_6193120_01

Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is RM352 per night from 16 Jun to 17 Jun
RM352
RM416 total
16 Jun - 17 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,389 reviews)
"The safety box never worked. The rest, perfect"

Reviewed on 2 Jun 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is RM425 per night from 11 Jun to 12 Jun
RM425
RM505 total
11 Jun - 12 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,069 reviews)
"Very good"

Reviewed on 1 Jun 2026

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is RM357 per night from 14 Jun to 15 Jun
RM357
RM422 total
14 Jun - 15 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,336 reviews)
"Totally worth the money with all the freebies you get."

Reviewed on 2 Jun 2026

Drury Inn & Suites San Antonio Northwest Medical Center
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is RM555 per night from 1 Jul to 2 Jul
RM555
RM656 total
1 Jul - 2 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,704 reviews)
"Absolutely the best hotel we’ve ever stayed in to include really nice and more expensive one in Los Vegas. My husband and I were celebrating our 54th wedding anniversary and wanted to be near the Riverwalk. This one, The Plaza, was right there off the basement elevator. Hotel food was great and readily ..."

Reviewed on 2 Jun 2026

Drury Plaza Hotel San Antonio Riverwalk
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is RM435 per night from 22 Jun to 23 Jun
RM435
RM628 total
22 Jun - 23 Jun
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (2,785 reviews)
"Great luxury hotel. It is a bit pricy. Although we had trouble with our mini-fridge it was broken, the hotel staff did respond the next day to fix it. We didnt get to use the occupancy fee credit that your automatically charged. Oh well. Great stay all around."

Reviewed on 2 Jun 2026

Hotel Valencia Riverwalk
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza San Antonio TX
The price is RM339 per night from 10 Jun to 11 Jun
RM339
RM400 total
10 Jun - 11 Jun
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the bar in their reviews. ...
8.8/10 Excellent! (4,081 reviews)
"Minimum eating in the hotel itself. Really missed the formal dining room that use to be open for brunch and dinner."

Reviewed on 1 Jun 2026

Menger Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

The Alamo in San Antonio, Texas

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Northwest Side
SanAntonio_NorthStarMall_502628_05

Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.

Shearer Hills - Ridgeview
River Walk in San Antonio, Texas

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio River or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
Texas Six Flags night light,2018

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
Tobin Hill

Tobin Hill

Tobin Hill might not have many top sights, but Alamo and San Antonio River are two attractions nearby that you can check out.

Tobin Hill
Dallas Skyline Reflection on Trinity River During Sunset, Dallas, Texas.

Uptown

If you're spending some time in Uptown, San Antonio River and Alamo Quarry Market are top sights worth seeing.

Uptown


Medical Center District