Top 10 Luxury Hotels in Ortygia for 2026

Check availability on Ortygia Luxury Hotels

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Ortygia luxury hotels

A poolside area with lounge chairs and umbrellas, a clear blue pool, and a building with balconies.

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Ortigia

Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.

RM3,144 total

includes taxes & fees

1 Nov - 2 Nov

A balcony with a view of the sea, a cactus, and potted plants.

2. Grand Hotel Ortigia Siracusa

Ortigia

Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.

RM1,233 total

includes taxes & fees

16 Nov - 17 Nov

A large, historic building with multiple floors, a prominent tower, and a waterfront marina with boats.

3. Ortea Palace Hotel, Sicily, Autograph Collection

Ortigia

Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.

RM1,352 total

includes taxes & fees

11 Nov - 12 Nov

A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.

4. Caportigia Boutique Hotel

Santa Lucia

Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.

RM728 total

includes taxes & fees

5 Nov - 6 Nov

An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.

5. Minareto

Syracuse

Syracuse seaside splendour offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.

RM1,443 total

includes taxes & fees

16 Nov - 17 Nov

A spa room with a large window, a hot tub, and two candles.

6. Dimora Caiammari Luxury Hotel & Spa

Syracuse

Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.

RM1,487 total

includes taxes & fees

1 Nov - 2 Nov

A large swimming pool with a modern building in the background.

7. Wellness & Spa Hotel Principe di Fitalia

Syracuse

Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness centre.

RM1,516 total

includes taxes & fees

17 Nov - 18 Nov

A stone-walled interior with a reception desk, two wall-mounted lamps, and a small table with a lamp.

8. Seven Rooms Villadorata

Noto

RM3,229 total

includes taxes & fees

7 Nov - 8 Nov

View all properties

Top Ortygia Hotel Reviews

Algila' Ortigia Charme Hotel

10/10 Excellent

"Awesome staff Very clean, great breakfast"

L'Approdo delle Sirene

10/10 Excellent

"Loved this hotel on the island of Ortigio. Very convenient to all the main sights. Entire city of Ortigio is Walkable and great restaurants nearby. Great breakfast and they offer access to car valet so you can drive up to the hotel and the valet picks up and then delivers the car back when you need it. Highly recommend it."

Grand Hotel Ortigia Siracusa

10/10 Excellent

"I enjoyed four unforgettable days exploring beautiful Ortigia -staying at the Grand Hotel Ortigia, which is a 5-star luxury hotel overlooking the harbor. It is just a short stroll to the must-see landmarks such as the ruins of the Temple of Apollo, the Aretusa Fountain, and the renowned Cathedral of Syracuse. it was built in 1890 and was completely renovated while preserving its classic old-world charm with marble floors, Corinthian columns, and beautiful art-filled common areas. They have an upscale rooftop restaurant and lounge on the third floor, which serves a sumptuous breakfast buffet and has great outdoor seating with spectacular views. I went up to the terrace one evening to enjoy the sunset with an Aperol Spritz and some nibbles and, after the sun went down, an exceptionally talented young man beautifully played his violin serenading the guests. Parking in the old city is a challenge, and not for the faint of heart. But the hotel does have a small lot nearby, but which seemed to stay full and was hard to find. With the helpful staff, I was able to register my rental car to allow me to drive to hotel which is in the restricted tourist zone and I moved my car to their lot one evening once the crowds had dissipated a bit. The staff couldn’t have been more helpful and even helped arrange a small group boat tour. This hotel truly deserves its name the Grand Hotel Ortigia Siracusa!"

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Ortygia Luxury Hotels

Our top choices for Ortygia luxury hotels

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

2. Grand Hotel Ortigia Siracusa

3. Ortea Palace Hotel, Sicily, Autograph Collection

4. Caportigia Boutique Hotel

5. Minareto

6. Dimora Caiammari Luxury Hotel & Spa

7. Wellness & Spa Hotel Principe di Fitalia

8. Seven Rooms Villadorata

9. Donna Coraly Country Boutique Hotel

10. Mangia's Brucoli, Sicily, Autograph Collection

Top Ortygia Hotel Reviews

Algila' Ortigia Charme Hotel

L'Approdo delle Sirene

Grand Hotel Ortigia Siracusa

Explore a world of travel with Expedia

Best Luxury Hotels in Ortygia

Change your mind

Treat yourself

Be picky

Check availability on Ortygia Luxury Hotels

Our top choices for Ortygia luxury hotels

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

2. Grand Hotel Ortigia Siracusa

3. Ortea Palace Hotel, Sicily, Autograph Collection

4. Caportigia Boutique Hotel

5. Minareto

6. Dimora Caiammari Luxury Hotel & Spa

7. Wellness & Spa Hotel Principe di Fitalia

8. Seven Rooms Villadorata

9. Donna Coraly Country Boutique Hotel

10. Mangia's Brucoli, Sicily, Autograph Collection

Top Ortygia Hotel Reviews

Algila' Ortigia Charme Hotel

Explore a world of travel with Expedia