A large eye sculpture in a park surrounded by trees.

Northeast Missouri Spa Hotels

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Check availability on Northeast Missouri Hotels with Spa

Tonight
17 Oct - 18 Oct
Tomorrow
18 Oct - 19 Oct
Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

Our top choices for Northeast Missouri hotels with a spa

A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.

1. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
  • Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
RM313
RM373 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A spacious lobby with a fireplace, seating area, and large windows.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.

2. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
  • Revitalising spa treatments await at this hotel, where an indoor pool, cosy pillow menus, and attentive staff create a relaxing retreat.
RM437
RM498 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Quincy East by IHG
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A two-story building with a dark entrance, large windows, and a brick facade.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

3. Truitt Hotel

Truitt Hotel
Lafayette Square
RM686
RM832 total
includes taxes & fees
18 Oct - 19 Oct
Truitt Hotel
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
RM586
RM706 total
includes taxes & fees
15 Nov - 16 Nov
21C Museum Hotel St Louis
A spa area with a massage table, a hot tub, and a grill.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.
A row of houses with a driveway leading to a gated entrance.
A living room with a fireplace, a dining area with a round table, and a balcony with a view.

5. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
RM1,286
RM1,478 total
includes taxes & fees
2 Nov - 3 Nov
Hermann Hill
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bar area with multiple seating arrangements, a stage, and a chandelier.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
RM650
RM827 total
includes taxes & fees
16 Nov - 17 Nov
Ameristar Casino Resort and Spa
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A couple standing on a balcony with a cityscape view.
A bar area with leather seating, a bar counter, and shelves of bottles.

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
RM2,363
RM2,759 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

8. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
RM1,531
RM1,790 total
includes taxes & fees
25 Oct - 26 Oct
Four Seasons Hotel St Louis
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Choose what matters most at spa hotels in Northeast Missouri

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with free breakfast in Northeast Missouri

A hotel room with a bed, a sofa, a desk, and a lamp.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
RM313
RM373 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A spacious lobby with a fireplace, seating area, and large windows.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
RM437
RM498 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Quincy East by IHG
A hot tub, a fire pit, and a view of a lake.
A row of houses with a driveway leading to a gated entrance.
A hotel room with a large bed, a bathtub, and a view of the outdoors.
A bathroom with a bathtub, a shower, and a vanity with a mirror.

Hermann Hill

Hermann Hill
Hermann
RM1,286
RM1,478 total
includes taxes & fees
2 Nov - 3 Nov
Hermann Hill
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
RM586
RM706 total
includes taxes & fees
15 Nov - 16 Nov
21C Museum Hotel St Louis
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A bar area with leather seating, a bar counter, and shelves of bottles.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.
A lobby with a fireplace, two armchairs, a round table, and a bench.

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
RM2,363
RM2,759 total
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Northeast Missouri Hotel Reviews

Moonrise Hotel

Moonrise Hotel

10/10 Excellent
"Had the Vincent Price suite with a city view. Also loved the rooftop terrace."
Mark 1-night trip
Posted 3 hours ago
Moonrise Hotel

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