Hotels in Murex Lakes, Sanibel

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Top 10 Hotels in Murex Lakes, Sanibel

On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4.0 star property
10.9 km from Murex Lakes
8.4 out of 10, Very good, (1003)
"This was thr best place that we have ever stayed at. "
United States
Matthew
The price is RM859
RM1,061 total
includes taxes & fees
14 Dec - 15 Dec
Marriott Sanibel Harbour Resort & Spa
Interior entrance
Allure Suites

Allure Suites

3.0 star property
23.6 km from Murex Lakes
7.6 out of 10, Good, (1002)
"Liked the friendly and fast check-in, spacious and clean suite, great location close to stores, soundproof rooms, greetings when I returned each day and reasonable room rates. I would stay again. "
United States
Charles
Allure Suites
Property amenity
TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

3.5 star property
29.6 km from Murex Lakes
9.4 out of 10, Exceptional, (459)
"The staff was very helpful. The room very clean. Close to restaurants and shopping. "
United States
Louis
The price is RM514
RM573 total
includes taxes & fees
14 Dec - 15 Dec
TownePlace Suites by Marriott Fort Myers Estero
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

3.0 star property
14.2 km from Murex Lakes
8.6 out of 10, Excellent, (1002)
"Clean room, wonderful staff, and nice breakfast. "
United States
Danielle
The price is RM391
RM436 total
includes taxes & fees
14 Dec - 15 Dec
Residence Inn by Marriott Fort Myers Sanibel
Outdoor pool
Days Inn by Wyndham Fort Myers Springs Resort

Days Inn by Wyndham Fort Myers Springs Resort

2.5 star property
26.7 km from Murex Lakes
6.0 out of 10, (1000)
"It was a really clean hotel "
United States
Tina
The price is RM309
RM344 total
includes taxes & fees
8 Dec - 9 Dec
Days Inn by Wyndham Fort Myers Springs Resort
Exercise/lap pool
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4.0 star property
26.3 km from Murex Lakes
9.2 out of 10, Wonderful, (722)
"Very pleasant staff, helpful, property well maintained. Great vacation spot with activities for the whole family. "
United States
Mutessa
The price is RM670
RM908 total
includes taxes & fees
8 Dec - 9 Dec
Hyatt Vacation Club at Coconut Cove, Bonita Springs
View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 star property
15.6 km from Murex Lakes
8.8 out of 10, Excellent, (1004)
"Great Place to Stay!"
United States
JUDY
The price is RM447
RM498 total
includes taxes & fees
14 Dec - 15 Dec
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Exterior
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

3.0 star property
14.7 km from Murex Lakes
8.0 out of 10, Very good, (1007)
"Room was clean and neat, very friendly staff."
United States
Olha
The price is RM451
RM503 total
includes taxes & fees
8 Dec - 9 Dec
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Exterior
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs

3.0 star property
29.2 km from Murex Lakes
8.8 out of 10, Excellent, (694)
"We enjoyed our stay. The accommodations were great!"
United States
Conny
The price is RM408
RM465 total
includes taxes & fees
14 Dec - 15 Dec
Latitude 26 Waterfront Boutique Resort - Bonita Springs
View from room
Matlacha on Shoreview

Matlacha on Shoreview

2.0 star property
23.2 km from Murex Lakes
9.6 out of 10, Exceptional, (207)
"Staff was very helpful throughout our stay, defnitley be back. Beautiful view, awesome area, very clean room."
United States
Randy
The price is RM185
RM481 total
includes taxes & fees
15 Dec - 16 Dec
Matlacha on Shoreview
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.5 star property
17.6 km from Murex Lakes
9.4 out of 10, Exceptional, (1001)
"Excellent room and price! Breakfast was great. Holiday Inn Express is doing everything right for a comfortable stay."
United States
Denise
The price is RM399
RM445 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Aerial view
DiamondHead Beach Resort

DiamondHead Beach Resort

3.5 star property
15.4 km from Murex Lakes
9.0 out of 10, Wonderful, (1002)
"Everything about this resort is spectacular! Staff, amenities, room! We had a wonderful stay!"
United States
Minda
DiamondHead Beach Resort
4 outdoor pools
Hyatt Regency Coconut Point Resort & Spa

Hyatt Regency Coconut Point Resort & Spa

4.5 star property
26.6 km from Murex Lakes
9.0 out of 10, Wonderful, (1001)
"This is a fabulous hotel in every way. The staff are outstanding especially Ursula who went out of her way to make sure we had what we needed. The hotel and it’s restaurants are wonderful. It is situated in the middle of beautiful groves with its on private island. Shopping is close by."
United States
Debra
The price is RM1,230
RM1,577 total
includes taxes & fees
15 Dec - 16 Dec
Hyatt Regency Coconut Point Resort & Spa
Exterior
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG

3.0 star property
20 km from Murex Lakes
7.4 out of 10, Good, (1002)
"Great place to stay."
United States
David
The price is RM382
RM426 total
includes taxes & fees
11 Dec - 12 Dec
Candlewood Suites Fort Myers Sanibel Gateway by IHG
Terrace/patio
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3.0 star property
25.7 km from Murex Lakes
8.8 out of 10, Excellent, (1002)
"Clean room super helpful staff"
United States
Tate R
The price is RM429
RM478 total
includes taxes & fees
14 Dec - 15 Dec
Hilton Garden Inn Ft Myers
Free buffet breakfast
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 star property
21.2 km from Murex Lakes
9.4 out of 10, Exceptional, (1021)
"Comfy bed, clean room, good breakfast "
United States
Darwin
The price is RM465
RM518 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Pillow-top beds, desk, iron/ironing board, free cots/infant beds
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 star property
28.7 km from Murex Lakes
6.6 out of 10, (1002)
"Location was great"
United States
Jake
The price is RM289
RM322 total
includes taxes & fees
31 Dec - 1 Jan 2026
Baymont by Wyndham Fort Myers Central
Terrace/patio
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 star property
14.9 km from Murex Lakes
9.0 out of 10, Wonderful, (1013)
"Clean rooms, friendly staff, so much to do there and nearby "
United States
Lisa R
The price is RM591
RM750 total
includes taxes & fees
8 Dec - 9 Dec
Lani Kai Beachfront Resort
Outdoor pool, open 7:00 AM to 6:00 PM, pool umbrellas, pool loungers
Hyatt Place Fort Myers Estero

Hyatt Place Fort Myers Estero

3.5 star property
29.1 km from Murex Lakes
8.8 out of 10, Excellent, (1001)
"Clean rooms freshly remodel staff very friendly breakfast bar was good as well and there a pet friendly hotel wich made my stay awesome with my fur baby and wife"
United States
Jose
The price is RM507
RM565 total
includes taxes & fees
17 Dec - 18 Dec
Hyatt Place Fort Myers Estero
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

3.0 star property
17.4 km from Murex Lakes
8.4 out of 10, Very good, (1001)
"Everything about this stay was wonderful. "
United States
John
The price is RM424
RM473 total
includes taxes & fees
13 Dec - 14 Dec
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Murex Lakes

Find the best Murex Lakes areas for the activities you enjoy most.
Fort Myers showing a sandy beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Murex Lakes Hotel Reviews

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

10/10 Excellent
"Clean, comfortable, and food was delicious. "
Laurel 2-night trip
Posted 3 days ago
The Lighthouse Resort Inn & Suites

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Frequently asked questions

What's it like in Murex Lakes?
You'll be sure to have fun exploring Sanibel's Murex Lakes neighbourhood.
How many hotels can I expect to find in Murex Lakes?
If you're searching for places to stay in Sanibel, choose from one of Expedia's 16 hotels and other accommodation options in Murex Lakes.
If I need to cancel my hotel reservation in Murex Lakes, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Murex Lakes.
What is there to do around this Sanibel neighbourhood?
Sanibel Captiva Conservation Foundation, Bailey - Matthews Shell Museum and Sanibel Island Southern Beach are just a few of the places to visit in and around Murex Lakes. When you're sightseeing in Sanibel, Sanibel Historical Museum and Village and Sanibel Historical Village and Museum are also worth a stop.