
Hotels in Medical Center District, San Antonio
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Medical Center District hotels

1. Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical CenterMedical Center District
9.2 out of 10, Wonderful, (1,532 reviews)
The price is RM365
RM436 total
includes taxes & fees
15 Nov - 16 Nov

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical CenterMedical Center District
9.0 out of 10, Wonderful, (1,113 reviews)
The price is RM382
RM446 total
includes taxes & fees
15 Nov - 16 Nov

3. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NWMedical Center District
8.4 out of 10, Very good, (3,780 reviews)
The price is RM360
RM430 total
includes taxes & fees
10 Nov - 11 Nov

4. Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San AntonioMedical Center District
8.8 out of 10, Excellent, (1,003 reviews)
The price is RM362
RM432 total
includes taxes & fees
26 Nov - 27 Nov

5. San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical CenterMedical Center District
8.6 out of 10, Excellent, (1,200 reviews)
The price is RM378
RM454 total
includes taxes & fees
10 Dec - 11 Dec

6. Park Inn by Radisson, Medical Center
Park Inn by Radisson, Medical CenterMedical Center District
7.4 out of 10, Good, (1,001 reviews)
The price is RM252
RM295 total
includes taxes & fees
1 Dec - 2 Dec

7. Motel 6 San Antonio, TX - Northwest Medical Center
Motel 6 San Antonio, TX - Northwest Medical CenterMedical Center District
6.0 out of 10, (1,003 reviews)
The price is RM187
RM239 total
includes taxes & fees
10 Nov - 11 Nov

8. Studio 6 San Antonio, Tx - Northwest Medical Center
Studio 6 San Antonio, Tx - Northwest Medical CenterMedical Center District
7.4 out of 10, Good, (406 reviews)
The price is RM207
RM242 total
includes taxes & fees
23 Nov - 24 Nov

9. Atria Inn & Suites
Atria Inn & SuitesMedical Center District
7.4 out of 10, Good, (321 reviews)
The price is RM281
RM329 total
includes taxes & fees
10 Nov - 11 Nov

10. Studio 6 Extended Stay - San Antonio, TX - Medical Center
Studio 6 Extended Stay - San Antonio, TX - Medical CenterMedical Center District
6.8 out of 10, (1,001 reviews)
The price is RM203
RM250 total
includes taxes & fees
10 Nov - 11 Nov

11. OYO Inn & Suites Medical Center San Antonio
OYO Inn & Suites Medical Center San AntonioMedical Center District
7.4 out of 10, Good, (251 reviews)
The price is RM231
RM293 total
includes taxes & fees
23 Nov - 24 Nov

12. Flex Studios
Flex StudiosMedical Center District
6.2 out of 10, (580 reviews)
The price is RM179
RM213 total
includes taxes & fees
10 Nov - 11 Nov

13. Hyatt Place San Antonio-Northwest/Medical Center
Hyatt Place San Antonio-Northwest/Medical Center3.7 km from Medical Center District
8.4 out of 10, Very good, (1,086 reviews)
The price is RM380
RM458 total
includes taxes & fees
26 Nov - 27 Nov

14. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB9 km from Medical Center District
9.2 out of 10, Wonderful, (1,172 reviews)
The price is RM422
RM494 total
includes taxes & fees
29 Nov - 30 Nov

15. Best Western Medical Center North Inn & Suites Near Six Flags
Best Western Medical Center North Inn & Suites Near Six FlagsNorthwest Side, 5.2 km from Medical Center District
8.2 out of 10, Very good, (1,616 reviews)
The price is RM270
RM316 total
includes taxes & fees
15 Nov - 16 Nov

16. Hampton Inn & Suites San Antonio Northwest/Medical Center
Hampton Inn & Suites San Antonio Northwest/Medical CenterNorthwest Side, 4.7 km from Medical Center District
8.6 out of 10, Excellent, (1,014 reviews)
The price is RM337
RM409 total
includes taxes & fees
22 Nov - 23 Nov

17. Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG
Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHGNorthwest Side, 4.3 km from Medical Center District
8.0 out of 10, Very good, (1,284 reviews)
The price is RM357
RM426 total
includes taxes & fees
15 Nov - 16 Nov

18. Drury Inn & Suites Near La Cantera Parkway
Drury Inn & Suites Near La Cantera ParkwayLa Cantera District, 9.5 km from Medical Center District
9.4 out of 10, Exceptional, (2,060 reviews)
The price is RM381
RM455 total
includes taxes & fees
22 Nov - 23 Nov

19. La Quinta Inn & Suites By Wyndham San Antonio At The Rim
La Quinta Inn & Suites By Wyndham San Antonio At The Rim11.9 km from Medical Center District
9.2 out of 10, Wonderful, (1,569 reviews)
The price is RM343
RM401 total
includes taxes & fees
6 Dec - 7 Dec

20. Courtyard by Marriott San Antonio Lackland
Courtyard by Marriott San Antonio Lackland6.5 km from Medical Center District
8.4 out of 10, Very good, (1,002 reviews)
The price is RM336
RM393 total
includes taxes & fees
15 Nov - 16 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Medical Center District
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Drury Inn & Suites San Antonio Northwest Medical Center | 9.2 Wonderful 1,532 reviews | View | ||||||
![]() Fairfield Inn & Suites by Marriott San Antonio Medical Center | 9.0 Wonderful 1,113 reviews | View | ||||||
![]() Courtyard by Marriott Medical Center San Antonio | 8.8 Excellent 1,003 reviews | View | ||||||
![]() San Antonio Marriott Northwest Medical Center | 8.6 Excellent 1,200 reviews | View | ||||||
![]() La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW | 8.4 Very good 3,780 reviews | View |
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown Central
If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
Top Medical Center District Hotel Reviews

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
10/10 Excellent


























































































