Hotels in Medical Center District, San Antonio

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hotels in Medical Center District, San Antonio

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
8.6 out of 10, Excellent, (2977)
"Great hotel and clean"
The price is RM374
RM442 total
includes taxes & fees
6 Oct - 7 Oct
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

San Antonio Marriott Northwest Medical Center

3.5 star property
8.6 out of 10, Excellent, (1003)
"Clean hotel."
The price is RM417
RM495 total
includes taxes & fees
6 Oct - 7 Oct
San Antonio Marriott Northwest Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1004)
"Staff was excellent "
The price is RM370
RM432 total
includes taxes & fees
26 Oct - 27 Oct
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1280)
"Friendly staff."
The price is RM379
RM448 total
includes taxes & fees
9 Oct - 10 Oct
Drury Inn & Suites San Antonio Northwest Medical Center

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.8 out of 10, Excellent, (1002)
"Great front desk service, very clean and spacious room, would definitely book again. "
The price is RM375
RM443 total
includes taxes & fees
12 Oct - 13 Oct
Courtyard by Marriott Medical Center San Antonio

Park Inn by Radisson

2.0 star property
7.2 out of 10, Good, (1002)
"Clean room and convenient to my dr's appointment "
The price is RM257
RM300 total
includes taxes & fees
2 Nov - 3 Nov
Park Inn by Radisson

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1002)
"Nice hotel"
The price is RM425
RM503 total
includes taxes & fees
5 Oct - 6 Oct
SpringHill Suites by Marriott San Antonio Medical Center/NW

Atria Inn & Suites

2.0 star property
7.6 out of 10, Good, (259)
"Nice and helpful staff "
Atria Inn & Suites

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (999)
"Really enjoyed our stay"
The price is RM184
RM217 total
includes taxes & fees
5 Oct - 6 Oct
Motel 6 San Antonio, TX - Northwest Medical Center

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1002)
"Hotel was in close vicinity of hospitals. Rooms.were good size and clean. Breakfast in the am. I Would definitely stay here again! "
The price is RM330
RM385 total
includes taxes & fees
18 Oct - 19 Oct
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.2 out of 10, Good, (183)
"The location was convenient and the price was very good. "
The price is RM219
RM255 total
includes taxes & fees
5 Oct - 6 Oct
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (754)
"The staff is great! Customer service is their forefront!"
The price is RM214
RM262 total
includes taxes & fees
14 Oct - 15 Oct
Studio 6 San Antonio, TX - Medical Center

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (218)
"Always great stay"
The price is RM251
RM307 total
includes taxes & fees
7 Oct - 8 Oct
OYO Inn & Suites Medical Center San Antonio

Flex Studios

2.5 star property
6.0 out of 10, (486)
"Staff was helpful checking in"
The price is RM183
RM216 total
includes taxes & fees
5 Oct - 6 Oct
Flex Studios

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 star property
9.0 out of 10, Wonderful, (1098)
"Great family friendly resort"
The price is RM336
RM571 total
includes taxes & fees
28 Oct - 29 Oct
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Courtyard by Marriott San Antonio SeaWorld - Westover Hills

3.0 star property
8.6 out of 10, Excellent, (1005)
"Will stay there again!"
The price is RM408
RM485 total
includes taxes & fees
12 Oct - 13 Oct
Courtyard by Marriott San Antonio SeaWorld - Westover Hills

La Quinta Inn & Suites by Wyndham San Antonio Northwest

3.0 star property
8.8 out of 10, Excellent, (1001)
"We have stayed before, and prefer this hotel and location"
The price is RM343
RM401 total
includes taxes & fees
12 Oct - 13 Oct
La Quinta Inn & Suites by Wyndham San Antonio Northwest

The Westin San Antonio North

4.0 star property
8.6 out of 10, Excellent, (1103)
"Beautiful hotel! Loved the price "
The price is RM344
RM412 total
includes taxes & fees
12 Oct - 13 Oct
The Westin San Antonio North

Days Inn by Wyndham Suites San Antonio North/Stone Oak

2.5 star property
8.0 out of 10, Very good, (1013)
"Nice quiet stay"
The price is RM222
RM259 total
includes taxes & fees
7 Oct - 8 Oct
Days Inn by Wyndham Suites San Antonio North/Stone Oak

La Quinta Inn & Suites By Wyndham San Antonio At The Rim

3.0 star property
9.2 out of 10, Wonderful, (652)
"I had a very nice stay."
The price is RM336
RM393 total
includes taxes & fees
6 Oct - 7 Oct
La Quinta Inn & Suites By Wyndham San Antonio At The Rim
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Fort Sam Houston

You'll love the stunning river views in Fort Sam Houston, and you might want to stick around to check out United States Army Medical Department Museum, a top place to visit.

Top Medical Center District Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is Medical Center District like?

Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.

What's a favourite hotel to stay in Medical Center District?

Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

How many hotels will I be able to find in Medical Center District?

Expedia has 119 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.

What can I see and do in this San Antonio neighbourhood?

USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.