Hotels near Main Street Cultural District

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28 Dec - 29 Dec
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Our top choices for Main Street Cultural District hotels

Premium bedding, pillow-top beds, desk, iron/ironing board
Iowa House

Iowa House

Iowa House
3.0 star property
3.1 km from Main Street Cultural District
9.6 out of 10, Exceptional, (818)
"Nice and clean room, very friendly staffs, and great breakfast!"
United States
Xiaoyu
Iowa House
Property amenity
SpringHill Suites by Marriott Ames

SpringHill Suites by Marriott Ames

SpringHill Suites by Marriott Ames
2.5 star property
2.9 km from Main Street Cultural District
9.4 out of 10, Exceptional, (542)
"Excellent facilities and staff."
United States
brent
The price is RM377
RM422 total
includes taxes & fees
31 Dec - 1 Jan 2026
SpringHill Suites by Marriott Ames
Exterior
Hampton Inn & Suites Ames

Hampton Inn & Suites Ames

Hampton Inn & Suites Ames
2.5 star property
3.2 km from Main Street Cultural District
9.4 out of 10, Exceptional, (563)
"Very nice clean hotel. "
United States
Shawn
The price is RM375
RM420 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hampton Inn & Suites Ames
Exterior
Courtyard by Marriott Ames

Courtyard by Marriott Ames

Courtyard by Marriott Ames
3.0 star property
2.1 km from Main Street Cultural District
9.2 out of 10, Wonderful, (286)
"Clean rooms with excellent staff service despite not having the bistro open"
United States
Kristin
The price is RM369
RM413 total
includes taxes & fees
25 Jan - 26 Jan 2026
Courtyard by Marriott Ames
BBQ/picnic Area
TownePlace Suites by Marriott Ames

TownePlace Suites by Marriott Ames

TownePlace Suites by Marriott Ames
3.0 star property
2.9 km from Main Street Cultural District
9.2 out of 10, Wonderful, (270)
"Wonderful place to stay "
United States
Lisa
The price is RM470
RM526 total
includes taxes & fees
2 Jan - 3 Jan 2026
TownePlace Suites by Marriott Ames
Premium bedding, pillow-top beds, desk, laptop workspace
Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus
2.5 star property
1.8 km from Main Street Cultural District
9.0 out of 10, Wonderful, (993)
"Very clean and close to where we wanted to visit. "
United States
Nancy
The price is RM341
RM382 total
includes taxes & fees
15 Jan - 16 Jan 2026
Comfort Inn and Suites Ames near ISU Campus
Restaurant
Staybridge Suites Ames by IHG

Staybridge Suites Ames by IHG

Staybridge Suites Ames by IHG
3.0 star property
3 km from Main Street Cultural District
8.8 out of 10, Excellent, (89)
"Very clean rooms, friendly staff, great Breakfast🤗"
United States
Sandy
The price is RM377
RM422 total
includes taxes & fees
31 Dec - 1 Jan 2026
Staybridge Suites Ames by IHG
Free daily on-the-go breakfast
Holiday Inn Express & Suites Ames by IHG

Holiday Inn Express & Suites Ames by IHG

Holiday Inn Express & Suites Ames by IHG
2.5 star property
3.2 km from Main Street Cultural District
8.6 out of 10, Excellent, (412)
"Great room and friendly staff"
United States
Brandi
The price is RM344
RM386 total
includes taxes & fees
31 Dec - 1 Jan 2026
Holiday Inn Express & Suites Ames by IHG
Lobby sitting area
Fairfield Inn & Suites by Marriott Ames

Fairfield Inn & Suites by Marriott Ames

Fairfield Inn & Suites by Marriott Ames
2.5 star property
3.2 km from Main Street Cultural District
8.6 out of 10, Excellent, (429)
"wonderful staff and amenities ,clean, easy access to the rest of the area."
United States
Clark
The price is RM340
RM381 total
includes taxes & fees
31 Dec - 1 Jan 2026
Fairfield Inn & Suites by Marriott Ames
Exterior
GrandStay Hotel & Suites

GrandStay Hotel & Suites

GrandStay Hotel & Suites
2.5 star property
2 km from Main Street Cultural District
8.4 out of 10, Very good, (1002)
"Large rooms."
United States
Cara
The price is RM281
RM314 total
includes taxes & fees
30 Dec - 31 Dec
GrandStay Hotel & Suites
Restaurant
Quality Inn & Suites Ames Conference Center Near ISU Campus

Quality Inn & Suites Ames Conference Center Near ISU Campus

Quality Inn & Suites Ames Conference Center Near ISU Campus
2.5 star property
3.2 km from Main Street Cultural District
7.0 out of 10, Good, (462)
"Friendly staff, easy check in"
United States
Michelle
The price is RM266
RM297 total
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn & Suites Ames Conference Center Near ISU Campus
In-room safe, desk, blackout curtains, iron/ironing board
Days Inn by Wyndham Ames

Days Inn by Wyndham Ames

Days Inn by Wyndham Ames
2.0 star property
0.6 km from Main Street Cultural District
6.2 out of 10, (939)
"Clean room,friendly staff "
United States
Brad
The price is RM263
RM295 total
includes taxes & fees
2 Jan - 3 Jan 2026
Days Inn by Wyndham Ames
Terrace/patio
Home2 Suites By Hilton Ames

Home2 Suites By Hilton Ames

Home2 Suites By Hilton Ames
3.0 star property
3.1 km from Main Street Cultural District
9.4 out of 10, Exceptional, (16)
"The rooms are always clean and the staff is always so nice and welcoming! We love staying here when we come to Ames. "
Canada
Sarah
The price is RM349
RM391 total
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites By Hilton Ames
View from property
Loya's Little House Bed & Breakfast

Loya's Little House Bed & Breakfast

Loya's Little House Bed & Breakfast
3.5 star property
11.2 km from Main Street Cultural District
10.0 out of 10, Exceptional, (24)
"The breakfast was outstanding. Very nice property. Comfortable beds and clean rooms. Would stay there again. "
United States
Kroczak
The price is RM365
RM383 total
includes taxes & fees
30 Dec - 31 Dec
Loya's Little House Bed & Breakfast
Living area
Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University
3.0 star property
3.4 km from Main Street Cultural District
9.2 out of 10, Wonderful, (1200)
"Great hotel! "
United States
Eileen
The price is RM324
RM363 total
includes taxes & fees
30 Dec - 31 Dec
Gateway Hotel and Conference Center at Iowa State University
Exterior
Spark by Hilton Ames

Spark by Hilton Ames

Spark by Hilton Ames
3.0 star property
3.5 km from Main Street Cultural District
9.0 out of 10, Wonderful, (22)
"Clean room nice staff. We would stay again in the future "
United States
Beverly
The price is RM296
RM331 total
includes taxes & fees
4 Jan - 5 Jan 2026
Spark by Hilton Ames
Exterior
Best Western Plus University Park Inn & Suites

Best Western Plus University Park Inn & Suites

Best Western Plus University Park Inn & Suites
2.5 star property
3.3 km from Main Street Cultural District
8.8 out of 10, Excellent, (1000)
"Staff was very courteous and very clean room."
United States
Scott
The price is RM316
RM354 total
includes taxes & fees
31 Dec - 1 Jan 2026
Best Western Plus University Park Inn & Suites
Desk, blackout curtains, iron/ironing board, free WiFi
Sleep Inn & Suites Ames near ISU Campus

Sleep Inn & Suites Ames near ISU Campus

Sleep Inn & Suites Ames near ISU Campus
2.5 star property
5.7 km from Main Street Cultural District
8.8 out of 10, Excellent, (1001)
"A nice quiet stay"
United States
Scott
The price is RM250
RM280 total
includes taxes & fees
18 Jan - 19 Jan 2026
Sleep Inn & Suites Ames near ISU Campus
Lobby
Hilton Garden Inn Ames

Hilton Garden Inn Ames

Hilton Garden Inn Ames
3.0 star property
5.6 km from Main Street Cultural District
8.6 out of 10, Excellent, (844)
"Very clean and nice amenities . Excellent restaurant and the hotel was so nicely decorated for Xmas "
United States
Laura
The price is RM402
RM451 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Ames
Indoor pool
AmericInn by Wyndham Ames

AmericInn by Wyndham Ames

AmericInn by Wyndham Ames
2.5 star property
3.5 km from Main Street Cultural District
8.4 out of 10, Very good, (1001)
"Yes yes very nice day will stay there again"
United States
Doss
The price is RM279
RM313 total
includes taxes & fees
30 Dec - 31 Dec
AmericInn by Wyndham Ames
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Main Street Cultural District Hotel Reviews

Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

10/10 Excellent
"Everything is good "
Austin 1-night trip
Posted 1 day ago
Stoney Creek Hotel Des Moines - Johnston

Hotels near other Main Street Cultural District attractions

Brunnier Art Museum

4.0/5 (2 reviews)
Be inspired by the decorative art exhibits at this university museum in central Iowa, where small-town America meets global culture.
See properties

Octagon Center for the Arts

3.6/5 (9 reviews)
You can spend an afternoon studying the exhibits at Octagon Center for the Arts during your travels in Ames. In the area, you can attend a football match or basketball game.
See properties

Frequently asked questions

What's the area like around Main Street Cultural District?
Main Street Cultural District is located in Ames. This family-friendly area is known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 26 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Cultural District?
Gateway Hotel and Conference Center at Iowa State University is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. It's located 2.1 mi (3.4 km) from Main Street Cultural District. Other good choices within 5 miles include Comfort Inn and Suites Ames near ISU Campus and SpringHill Suites by Marriott Ames.
How many hotels will I be able to find near Main Street Cultural District?
Expedia has 26 hotels and other accommodation options within a mile from Main Street Cultural District.
If I need to cancel the hotel reservation for my stay near Main Street Cultural District, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Main Street Cultural District.
What can I see and do near Main Street Cultural District?
You'll want to browse the exhibits at Farm House Museum and Brunnier Art Museum. If you have some time to wander around the area, you might stop by Hilton Coliseum, Jack Trice Stadium or Veenker Memorial Golf Course. Iowa State Center and Stephens Auditorium are some sights worth a visit in the area.