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Hotels in Lake Nona Medical City, Orlando

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Check prices for these dates

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

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Our top choices for Lake Nona Medical City hotels

Exterior

1. Aloft by Marriott Orlando Lake Nona

Aloft by Marriott Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (464 reviews)
"nice clean hotel, close to restaurants"
United States
Ali
The price is RM564
RM641 total
includes taxes & fees
8 Nov - 9 Nov
Aloft by Marriott Orlando Lake Nona
A swimming pool with sun loungers and palm trees.

2. Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (664 reviews)
"We had an amazing stay! Room was so nice and the perfect location! I dropped off balloons a day early to have in the room as a birthday surprise and the staff was so accommodating and nice! Shout out to Stephen who was great!"
United States
Christine
The price is RM653
RM742 total
includes taxes & fees
26 Nov - 27 Nov
Courtyard Orlando Lake Nona
A swimming pool with sun loungers and palm trees, surrounded by a modern building.

3. Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (347 reviews)
"Hotel was very nice."
United States
Christine
The price is RM730
RM830 total
includes taxes & fees
22 Nov - 23 Nov
Residence Inn Orlando Lake Nona
Room

4. Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (4,331 reviews)
"Stay was very pleasant"
United States
Rosacruz
The price is RM362
RM407 total
includes taxes & fees
1 Nov - 2 Nov
Wingate by Wyndham - Orlando International Airport
An outdoor seating area with green chairs and umbrellas, a fire pit, and a building with large windows in the background.

5. Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,928 reviews)
"Clean room, friendly staff, and great breakfast options"
United States
Imran
The price is RM445
RM501 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Orlando Airport @ Gateway Village
An outdoor patio area with seating, a bar, and a fire feature.

6. Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.5 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (2,846 reviews)
"Great place to stay."
United States
CHRIS
The price is RM560
RM630 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt House Orlando Airport
A spacious lobby with a wooden staircase, a reception desk, and a large wall clock.

7. Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL
3.0 star property
Airport North, 11 km from Lake Nona Medical City
8.0 out of 10, Very good, (5,117 reviews)
"The room was spacious, so convenient to the airport, very clean, near eateries plus food trucks for a quick bite and staff was so helpful."
United States
Patrice
The price is RM314
RM353 total
includes taxes & fees
16 Nov - 17 Nov
Country Inn & Suites by Radisson, Orlando Airport, FL
A modern hotel room with a large bed, a nightstand, a drawer, a wall-mounted light, and a window with a view of trees.

8. Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport
3.0 star property
Airport North, 10.4 km from Lake Nona Medical City
8.2 out of 10, Very good, (6,193 reviews)
"close to airport, good night's sleep, good breakfast, nice room layout"
United States
Barbara
The price is RM317
RM357 total
includes taxes & fees
1 Dec - 2 Dec
Ramada by Wyndham Suites Orlando Airport
A hotel with a prominent tower, palm trees, and a red roof.

9. La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport
3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.6 out of 10, Good, (2,908 reviews)
"Clean rooms, nice breakfast, and airport shuttle."
United States
Angella
The price is RM198
RM223 total
includes taxes & fees
23 Nov - 24 Nov
La Quinta Inn & Suites by Wyndham Orlando Airport
A modern living room with a stone fireplace, a sofa, a coffee table, and a lamp.

10. Fairfield Inn By Marriott Orlando Airport

Fairfield Inn By Marriott Orlando Airport
3.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,641 reviews)
"The staff was very friendly and breakfast was pretty good!"
United States
Eddie
The price is RM341
RM384 total
includes taxes & fees
29 Nov - 30 Nov
Fairfield Inn By Marriott Orlando Airport
A Holiday Inn Express building with a modern design, featuring a prominent entrance and a covered walkway.

11. Holiday Inn Express Orlando International Airport by IHG

Holiday Inn Express Orlando International Airport by IHG
2.5 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,038 reviews)
"Wonderful 3 night stay. Very friendly staff"
United States
Andrea
The price is RM398
RM447 total
includes taxes & fees
1 Dec - 2 Dec
Holiday Inn Express Orlando International Airport by IHG
A modern kitchen with a central island, bar stools, and pendant lighting.

12. Wyndham Garden Orlando Airport

Wyndham Garden Orlando Airport
3.0 star property
Belle Isle, 11.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (4,213 reviews)
"Excellent staff, dining options and clean property with convenient location."
United States
Linette
The price is RM357
RM402 total
includes taxes & fees
3 Nov - 4 Nov
Wyndham Garden Orlando Airport
A hotel lobby with a gallery wall, seating areas, and a reception desk.

13. Holiday Inn Orlando International Airport by IHG

Holiday Inn Orlando International Airport by IHG
3.5 star property
Airport North, 10.8 km from Lake Nona Medical City
8.4 out of 10, Very good, (1,541 reviews)
"Nice room and the service staff were excellent."
United States
Raul
The price is RM381
RM429 total
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Orlando International Airport by IHG
A modern hotel with a red carpet leading to the entrance, a wooden walkway, and a clear view of the building's facade.

14. EVEN Hotel Orlando International Airport by IHG

EVEN Hotel Orlando International Airport by IHG
3.5 star property
Airport North, 11.1 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (966 reviews)
"Good hotel"
United States
Bryan
The price is RM376
RM423 total
includes taxes & fees
1 Nov - 2 Nov
EVEN Hotel Orlando International Airport by IHG
A modern kitchen with wooden cabinets, a central island, and a breakfast bar.

15. Hampton Inn Orlando-International Airport

Hampton Inn Orlando-International Airport
2.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,196 reviews)
"Very comfortable beds and bedding as well"
United States
Paula
The price is RM394
RM444 total
includes taxes & fees
30 Nov - 1 Dec
Hampton Inn Orlando-International Airport
A modern hotel lobby with a large flat-screen TV, a blue sofa, a round wooden table, and a curved reception desk.

16. Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
11.1 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2,018 reviews)
"Loved our stay, check in was super duper easy and the bed was soo comfy!"
United States
Seth
The price is RM386
RM435 total
includes taxes & fees
25 Nov - 26 Nov
Cambria Hotel Orlando Airport
A modern dining area with a large table, chairs, and a coffee station.

17. avid hotel Orlando International Airport by IHG

avid hotel Orlando International Airport by IHG
2.5 star property
11.2 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (2,180 reviews)
"Airport shuttle was nice, the hotel was very clean"
United States
Jamie
The price is RM369
RM415 total
includes taxes & fees
1 Dec - 2 Dec
avid hotel Orlando International Airport by IHG
Business centre

18. Comfort Suites Orlando International Airport

Comfort Suites Orlando International Airport
2.5 star property
Belle Isle, 12 km from Lake Nona Medical City
8.4 out of 10, Very good, (1,333 reviews)
"The staff were friendly and helpful, the room was large and clean, the beds were comfortable and the breakfast was decent. I would stay here again."
Canada
ALEXANDER
The price is RM348
RM392 total
includes taxes & fees
23 Nov - 24 Nov
Comfort Suites Orlando International Airport
A hotel room with two beds, a flat-screen TV, a desk, and a lamp.

19. Sonesta Essential Orlando Airport

Sonesta Essential Orlando Airport
3.0 star property
12.2 km from Lake Nona Medical City
8.0 out of 10, Very good, (1,314 reviews)
"Great place to stay close to the airport. The breakfast was amazing,"
United States
ian
The price is RM361
RM406 total
includes taxes & fees
3 Nov - 4 Nov
Sonesta Essential Orlando Airport
An aerial view of a resort with multiple swimming pools, landscaped gardens, and outdoor seating areas.

20. Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
16.9 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (4,990 reviews)
"Great staff, location, resort was amazing"
United States
Dominic
The price is RM484
RM544 total
includes taxes & fees
24 Nov - 25 Nov
Rosen Shingle Creek
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Lake Nona Medical City

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Aloft by Marriott Orlando Lake Nona
3.0 star property
9.6
Exceptional
464 reviews
View
A swimming pool with sun loungers and palm trees.
Courtyard Orlando Lake Nona
3.0 star property
9.6
Exceptional
664 reviews
View
A swimming pool with sun loungers and palm trees, surrounded by a modern building.
Residence Inn Orlando Lake Nona
3.0 star property
9.6
Exceptional
347 reviews
View
An aerial view of a resort with multiple swimming pools, landscaped gardens, and outdoor seating areas.
Rosen Shingle Creek
4.5 star property
9.6
Exceptional
4,990 reviews
View
A hotel pool area with lounge chairs and umbrellas, surrounded by tall buildings and a sunset sky.
Drury Plaza Hotel Orlando - Disney Springs Area
4.0 star property
9.8
Exceptional
6,201 reviews
View

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas for the activities you enjoy most.
The entrance to the Hollywood Studios area with a large sign and distinctive architecture.
Photo by Gary Burke
Open Photo by Gary Burke

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

A large Ferris wheel with blue lights, surrounded by a cityscape with illuminated buildings and a tall green tower.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

A roller coaster at Universal Orlando Resort, featuring a tall palm tree and a clear blue sky.
Photo by Peter Sutton
Open Photo by Peter Sutton

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

A large Ferris wheel with blue lighting, surrounded by a parking lot and buildings.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

A golf course with bunkers, water hazards, and a large lake.

Reunion

The top golf courses and fun-filled water parks are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

Top Lake Nona Medical City Hotel Reviews

Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

10/10 Excellent
"We have been staying at Cabana Bay for the past 3 years for HHN it is super easy to get to the park and back, buses are always running and they Bayline diner has different types of food even at 0300 when you comeback tired from the parks."
Yorika 2-night trip
Posted 2 hours ago
Universal's Cabana Bay Beach Resort

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighbourhood that travellers like for its restaurants.
What's the best accommodation in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favourite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels will I find in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodation options, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Lake Nona Medical City.
What is there to do around this Orlando neighbourhood?
Eagle Creek Golf Club, USTA National Campus and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.

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